Neuromyelitis Optica Spectrum Disorder: Management Updates and Challenging Clinical Cases

1.00 CME

60 MINS

SAVE

Overview

Provider Statement

This continuing education activity is provided by Vindico Medical Education

Support Statement

This activity is supported by an educational grant from Genentech, a member of the Roche Group.

Activity Description

Neuromyelitis optica spectrum disorder (NMOSD) is a rare, relapsing, autoimmune disease of the central nervous system that mainly manifests through recurrent attacks of optic neuritis and longitudinally extensive transverse myelitis. NMOSD is often misdiagnosed in the early stages, but the integration of newer diagnostic criteria may assist in an earlier and more accurate differential diagnosis. Until recently, treatment options for NMOSD have been limited―but several approved biologic therapies have now demonstrated efficacy and safety in these patients. In this CE activity, experts in the field will review evidence-based criteria for diagnosis NMOSD as well as risk factors associated with relapse frequency and prognosis, and evaluate therapeutic options based on the latest efficacy and safety data, along with their ability to control acute attacks and prevent future relapses.

Target Audience

The intended audience for this activity is neuro-ophthalmologists, ophthalmologists, neurologists, and other healthcare professionals involved in the management of patients with neuromyelitis optica spectrum disorder (NMOSD).

Learning Objectives

Upon successful completion of this activity, participants should be better able to:

Review evidence-based criteria for diagnosing NMOSD as well as risk factors associated with relapse frequency and prognosis.
Select therapy for patients with NMOSD based on the latest efficacy and safety data, including the ability to control acute attacks and prevent future relapses.

Activity Chair

Prem S. Subramanian, MD, PhD
Clifford R. and Janice N. Merrill Endowed Chair in Ophthalmology
Professor of Ophthalmology, Neurology, and Neurosurgery
University of Colorado School of Medicine
Vice Chair for Academic Affairs
Division Head, Neuro-Ophthalmology
University of Colorado Sue Anschutz-Rodgers Eye Center
Aurora, CO

Faculty

Fiona Costello, MD, FRCPC
Professor, Departments of Clinical Neurosciences and Surgery
Associate Dean (Chairs and Professorships)
Cumming School of Medicine
University of Calgary
Calgary, Alberta, Canada

Benjamin M. Greenberg, MD, MHS, FANA, FAAN, CRND
Distinguished Teaching Professor
Vice Chair for Clinical and Translational Research
Department of Neurology
Director, Perot Foundation Neurosciences Translational Research Center
O’Donnell Brain Institute
University of Texas Southwestern
Dallas, TX

Planner/Reviewer

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP

Accreditation

ACCME Jointly accredited In support of improving patient care, Vindico Medical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, April 18, 2023, to April 17, 2024.

How to Participate in This Activity and Obtain CME Credit

To participate in this CME activity, you must read the objectives, answer the polling and pretest questions, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 3 of the 4 posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ certificate.

Disclosures

Vindico Medical Education adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a continuing education activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Relationship information is accurate at the time of content development.

Activity Chair and Faculty report the following relevant financial relationship(s)

Fiona Costello, MD, FRCPC
Consultant: Alexion, Frequency Therapeutics, Novartis, Sanofi

Benjamin M. Greenberg, MD, MHS, FANA, FAAN, CRND
Advisor: Siegel Rare Neuroimmune Association
Consultant: Alexion, Cycle Pharmaceuticals, EMD Serono, Genentech/Roche, Genzyme, Horizon, Immunovant, Novartis, Sandoz, TG Therapeutics
Independent Research Contractor: Anokion, Clene Nanomedicine

Prem S. Subramanian, MD, PhD
Consultant: GenSight Biologics, Horizon, Invex Therapeutics, Kriya, Viridian
Independent Research Contractor: GenSight Biologics, Horizon, Immunovant, Invex Therapeutics, Viridian

Planner/Reviewer reports the following relevant financial relationship(s)

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.

Vindico Medical Education staff report the following relevant financial relationship(s)

No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Unlabeled and Investigational Usage

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)–approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2023 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.