Cytokines, Janus Kinase Inhibitors, and Small-Molecule Therapies, Oh My!: New Inroads Into Rheumatoid Arthritis Management

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Overview / Abstract:

Although the introduction of biologic agents has transformed treatment paradigms for rheumatoid arthritis (RA), a considerable proportion of patients do not respond sufficiently to these therapies. A potential new therapeutic alternative for these patients is small-molecule inhibitors, which offer targeted inhibition of intracellular pathways that can be achieved via oral administration. To realize the benefits of small-molecule inhibitor therapy, it is essential for clinicians to know how these agents target cytokine signaling and intracellular pathways.

This activity contains three interactive modules designed to help clinicians understand the mechanisms of action of small-molecule inhibitors and to recognize how these agents fit into established RA management guidelines.

Expiration

Aug 02, 2018

Discipline(s)

Nurse Practitioner , Physician CME, Physician Assistant CME

Format

Online

Credits / Hours

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Chicago Pritzker School of Medicine and RedMedEd. The University of Chicago Pritzker School of Medicine is accredited by the ACCME to provide continuing medical education for physicians. The University of Chicago Pritzker School of Medicine designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Accreditation

ACCME

Is This Activity Certified for "Live" Credit?

YES

Presenters / Authors / Faculty

Anisha B. Dua, MD, MPH—Program Chair
Assistant Professor, Department of Rheumatology
Fellowship Program Director
Director of the Vasculitis Center
University of Chicago
Chicago, Illinois

Eric M. Ruderman, MD
Professor of Medicine
Associate Chief, Clinical Affairs
Division of Rheumatology
Feinberg School of Medicine
Clinical Practice Director
Northwestern Medical Faculty Foundation
Chicago, Illinois

Mary Chester M. Wasko, MD
Clinical Professor of Medicine
Temple University School of Medicine
Division Director, Rheumatology
Philadelphia, Pennsylvania

Activity Specialities / Related Topics

Education / Teaching, Family Medicine, Internal Medicine, Primary Care, Rheumatology / Arthritis

Sponsors / Supporters / Grant Providers

Support for this activity has been provided through an independent educational grant from Pfizer.

Keywords / Search Terms

RedMedEd RedMedEd, rheumatoid arthritis, RA, small-molecule inhibitors, small-molecule inhibitor therapy, clinicians, mechanisms of action, RA management guidelines, rheumatoid arthritis management guideline, cytokine signals, inflammation, biologics, Free CE, CME Free CE CME Live CE CME

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