Leveraging BCMA-Directed Therapies for Improved Patient Outcomes in Relapsed/Refractory Multiple Myeloma
STATEMENT OF NEED
Multiple myeloma is a disease that remains incurable for most patients, many of whom become refractory to the majority of available treatments (Kumar et al, 2022). It is estimated that 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Agents targeting B-cell maturation antigen (BCMA), including antibody-drug conjugates (ADCs), chimeric antigen receptor (CAR) T-cell therapies, and bis... |
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Expert Guidance on Current Standards and New Directions in Newly Diagnosed Multiple Myeloma
STATEMENT OF NEED
An estimated 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Characterized by clonal proliferation of malignant plasma cells in the bone marrow, multiple myeloma is associated with anemia, renal insufficiency, bone destruction, and hypercalcemia, all of which significantly impact patients’ quality of life. The development of novel therapies and combinations in recent years, inclu... |
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Myasthenia Gravis Research Highlights: AAN 2023
This 30-minute CME program highlights the latest clinical research about myasthenia gravis, a rare, autoimmune disease that targets the neuromuscular junction.
Treatment of myasthenia gravis is highly individualized and depends greatly on the myasthenia gravis subtype of each patient as well as each patient’s comorbidities. There are currently four drugs approved by the FDA, eculizumab, efgartigimod, ravulizumab, and rozanolixizumab. There are also treatments in development. Clinical tria... |
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Leveraging the Growing Arsenal of Adjuvant Therapies for Early-Stage NSCLC
In this activity, Dr. Helena A. Yu, Associate Attending Physician at Memorial Sloan Kettering Cancer Center, will provide insights into strategies for leveraging the growing arsenal of adjuvant therapies for early-stage non"small cell lung cancer (NSCLC), including treatment selection and adverse event management. Start the activity now!
STATEMENT OF NEED
Lung cancer is the second most commonly diagnosed cancer and the leading cause of death for men and women worldwide. In the Unite... |
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Acromegaly Research Highlights: ENDO 2023
This 30-minute CME-accredited program highlights the latest clinical research about acromegaly, a rare endocrine disorder. Common symptoms include subtle skeletal overgrowth; soft tissue swelling (tongue, heart, kidney, colon, and vocal cords); unusually prominent forehead and heavy brow ridge; protruding lower jaw; overbite; skin thickening; increased shoe and ring size; hypertension; increased perspiration; headaches; paresthesia; and sexual dysfunction.
There are several orphan drugs app... |
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Exploring Novel Treatments for Rett Syndrome
STATEMENT OF NEED
Rett syndrome is a rare, debilitating neurodevelopmental disorder almost always associated with a spontaneous mutation in the methyl-CpG-binding protein 2 (MECP2) gene on the X-chromosome. Affected individuals experience loss of purposeful hand skills, abnormalities in gait, loss of spoken language, and stereotypic hand movements, with more severe manifestations including seizures, autistic features, autonomic nervous system dysfunction, breathing abnormalities, sleep dist... |
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Updates in Hereditary Angioedema Care from HAEA
Target Audience
This activity is designed to meet the educational needs of clinicians involved in the diagnosis and management of patients with hereditary angioedema (HAE).
Program Overview
This activity will cover HAE genetics and diagnostics with a focus on HAE-nl-C1INH, emerging therapies, and patient-centered care.
Learning Objectives
Upon completion of this activity, participants should be better able to:
Integrate new developments in hereditary angioedema (HAE) genetic and di... |
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Right Treatment, Right Patient: Evidence-Based Approaches to the Treatment of Moderate-to-Severe Atopic Dermatitis
Target Audience
This activity is designed to meet the educational needs of dermatology and allergy physicians, nurse practitioners, PAs and nurses who care for patients with moderate-to-severe atopic dermatitis.
Program Overview
A 2-part online enduring module that provides learners with evidence related to current and emerging treatment options for moderate-to-severe atopic dermatitis, as well as interactive and engaging cases that challenge learners to apply the information to realistic... |
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Principles of Medical Education: Maximizing Your Teaching Skills - LIVE STREAMING
The Techniques and Strategies that Significantly Improve Student Engagement and Teaching and Mentoring Effectiveness
This special program, ranked among Harvard Medical School’s highest-rated CME courses, is a uniquely comprehensive exploration of best practices for teaching medicine at the bedside, in ambulatory settings, and in the classroom.
PLEASE NOTE: Enrollment for this live streaming course is limited. Early registration is advised.
The 2024 curriculum helps medical educato... |
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Current Management of Domestic Violence - Responding to IPV
This course helps you screen for, respond to, document, and manage your patients who are suffering from abusive relationships. Includes up to 17 patient cases in 5 different specialties.
Outcome Objectives:
As a result of completing this activity, the participant will be better able to:
- Screen patients for intimate partner violence (IPV) and appropriately respond to disclosures of abuse.
- Recognize patterns of abuse and properly document IPV.
- Assess the safety of IPV victims.
... |
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Clinical Evidence for COVID PrEP, With Drs. Leonard Calabrese and Myron Cohen
In this podcast, expert clinicians will review recent developments involving monoclonal antibody therapies for COVID-19 and discuss ongoing studies on pre-exposure prophylaxis for immunocompromised patients. |
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Build Your Own Case Study | Obesity: Treating the Whole Patient
Activity Description
Obesity is a chronic, progressive, relapsing disease that impacts health and quality of life. In individuals with obesity, there are many contributors to its development and persistence, including lifestyle, social, and economic factors. If left untreated, obesity can be a primary driver of serious health consequences. By treating obesity first, complications arising from obesity may improve or resolve. Given the severity of the disease, there is a need for clinicians in ... |
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Tracking and Treating Uveitic Macular Edema: A Difficult Dilemma
Uveitic macular edema (UME) has a wide variety of causes. If not appropriately treated, it eventually causes damage to the photoreceptors in the macula, resulting in vision-threatening complications like macular ischemia or macular hole formation. Corticosteroids are the first-line treatment for uveitic inflammation and UME. However, they are not generally considered to be appropriate for long-term treatment due to adverse effects, including increased intraocular pressure and cataract in local... |
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Tracking and Treating Uveitic Macular Edema: A Difficult Dilemma
Uveitic macular edema (UME) has a wide variety of causes. If not appropriately treated, it eventually causes damage to the photoreceptors in the macula, resulting in vision-threatening complications like macular ischemia or macular hole formation. Corticosteroids are the first-line treatment for uveitic inflammation and UME. However, they are not generally considered to be appropriate for long-term treatment due to adverse effects, including increased intraocular pressure and cataract in local... |
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Office Practice of Primary Care Medicine 2024 - LIVE STREAMING
The Comprehensive 2024 Update on Office-Based Primary Care Medicine
Taught Live Online by Harvard Medical School's Leading Clinical Faculty
Office Practice of Primary Care Medicine will be held online this year, using live streaming, electronic Q&A, and other remote learning technologies.
OVERVIEW
Office Practice of Primary Care Medicine provides comprehensive reviews of the most important recent advances impacting primary care medicine and guidance to assimilate these changes... |
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Skin Cancer Education for Primary Care
This comprehensive course on skin cancer will help you improve your ability to diagnose and manage skin lesions, the most common of all cancers.
Outcome Objectives:
As a result of completing this activity, the participant will be better able to:
- Understand the biology of ultraviolet radiation and methods to protect the skin.
- Demonstrate increased proficiency in the management of potentially malignant skin lesions.
- Make early diagnoses of skin cancers, particularly melanoma.... |
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Right Treatment, Right Patient: Evidence-Based Approaches to the Treatment of Moderate-to-Severe Atopic Dermatitis Snippet 1: Currently Available Injectable Biologic Therapies for Moderate-to-Severe Atopic Dermatitis (AD)
Target Audience
This activity is designed to meet the educational needs of dermatology and allergy physicians, nurse practitioners, PAs, and nurses who care for patients with moderate-to-severe atopic dermatitis.
Program Overview
This activity features a case presentation, a brief overview of currently available injectable biologic therapies, and insights from an expert faculty.
Learning Objectives
After completing this activity, the participant should be better able to::
Identify ... |
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Anesthesiology Update 2024 - LIVE STREAMING or IN PERSON
The Comprehensive 2024 Anesthesiology Update
Cardiac, Regional, Office-Based, Thoracic, Obstetric, Neuro, and Pediatric
Anesthesiology Update will be held on May 6-10, 2024. You have the option to attend either online as the course is live streamed or in person in Boston, MA.
In the past year, there have been a number of very significant clinical changes that affect the practice of anesthesiology. This comprehensive CME program provides a special and timely opportunity for anesthesiolo... |
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Duchenne Muscular Dystrophy: Recognizing Its Earliest Signs in Infancy and Care Transition into Adulthood
Target Audience
The intended audience for this activity are neurologists, neuromuscular specialists, pediatric neurologists, genetic counselors, and pediatricians.
Program Overview
Join a panel of expert clinicians to identify the subtle and very early signs of DMD that may be detected before functional symptoms are noticed and that can help earlier diagnoses and appropriate interventions. Panelists will review the importance of matching mutations to therapeutic decisions, discuss emergin... |
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Parkinson’s Disease " Updates in Diagnosis and Patient Management
Parkinson's disease is a neurodegenerative disorder, second only in prevalence to Alzheimer’s disease. Numerous therapeutic options, including carbidopa/levodopa, monoamine oxidase-B inhibitors, dopamine agonists, and device-assisted therapies, are available for treatment. These treatments are indicated at different stages following diagnosis. However, Parkinson’s disease progresses at highly variable rates, and no biomarkers, laboratory tests, or gold standard indexes are available t... |
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Diabetes Update 2024 - LIVE STREAMING
This highly rated Harvard Medical School CME course offers practical strategies to address the medical and systemic challenges to optimal care and updates that ensure you can deliver state-of-the-art care for your patients with diabetes.
PROGRAM HIGHLIGHTS
This program affords you the opportunity to learn from leaders in the field of diabetes who are distinguished for their outstanding teaching, knowledge, and innovations in clinical care.
Participants can rely on this program for compreh... |
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Eyeing the Options for Treating Meibomian Gland Dysfunction and Dry Eye Disease
Dry eye disease (DED) is highly prevalent but frequently underdiagnosed and subsequently undertreated. Studies have demonstrated that meibomian gland dysfunction (MGD) is a leading cause of the development and progression of evaporative DED, caused by a deficient tear film lipid layer that leads to increased tear evaporation. New and emerging treatments with novel mechanisms of action are being investigated that manage the signs and symptoms of DED associated with MGD and offer the potential f... |
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Warm Autoimmune Hemolytic Anemia (wAIHA)
Target Audience
This activity has been designed to meet the educational needs of physicians specializing in hematology and hematology-oncology. Other members of the care team may also participate.
Program Overview
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis.
Current recommendations for managing ... |
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ACTHIV
The American Conference for the Treatment of HIV: ACTHIV® is the premier conference in the US dedicated exclusively to the frontline care team and its members who are caring for persons living with or at risk of acquiring HIV. This aids management conference delivers information on new developments and research findings that can be rapidly translated and directly applied to the clinical setting. |
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Optimizing Transition from Pediatric to Adult Care - LIVE STREAMING
In this special program, faculty from Harvard Medical School, the Brigham Transition Care Team, and the Boston Children’s Hospital BRIDGES Adult Transition Program provide strategies, best practices, and guidance to:
• Identify adult care providers and successfully transfer patients with rare or complex health care needs
• Assess and improve the efficacy of your current transition processes
• Tailor transition strategies to patient age, disease type, and physical/ intellectual capab... |
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Innovations and New Practices in Internal Medicine 2024 -LIVE STREAMING
The State of the Art in Internal Medicine
This program, which is among the highest-rated Harvard Medical School CME courses, provides a comprehensive update of the most important changes now impacting Internal Medicine and guidance on how to incorporate these changes into your clinical practice to improve patient outcomes..
Practical, Fast-Paced, Online Education
This live streaming educational experience is fast paced, relevant to the current healthcare environment, and draws upon real... |
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Vision For Life: Maintaining Healthy Eyes in Diabetes
Program Overview
This online program is designed to help primary care clinicians who manage patients who have or are at risk for diabetic eye disease. Learn about the importance of early detection and recommended screening guidelines, how to identify patients at higher risk for diabetic eye disease, and multidisciplinary management options to help patients with diabetes preserve vision.
Learning Objectives
After completing the CME activity, learners should be better able to:
Examine th... |
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WEBINAR BUNDLE: Veterinary Pharmacy Conference 2021 - On Demand
Earn up to 7 hours of continuing education focused on community veterinary pharmacy when you purchase the Veterinary Pharmacy Conference 2021 - On Demand.
The ACVP Veterinary Pharmacy Virtual Conference is the only national conference designed exclusively for community veterinary pharmacies, ideal for new and established veterinary pharmacy practices. This conference is designed for pharmacists and pharmacy technicians and presents the latest clinical and practical topics.
Session 1 -... |
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A Breath of Fresh Air: Novel Treatments That Address the Inflammatory Component of Non-Cystic Fibrosis Bronchiectasis
Non-cystic fibrosis bronchiectasis (NCFBE) is a heterogenous and increasingly prevalent chronic pulmonary disease that is associated with high morbidity and mortality. It is characterized by irreversibly damaged and dilated bronchi, and has a broad spectrum of clinical presentations, ranging from asymptomatic radiological changes detected incidentally to chronic sputum production and recurrent exacerbations. There are numerous etiologies that can induce or contribute to the pathophysiological ... |
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In Case You Missed: Utilizing the Muscarinic System to Optimize Treatment Options for Schizophrenia
Schizophrenia is an incurable, neuropsychiatric disease characterized by difficulties thinking and communicating clearly as well as psychosis (ie, “positive” symptoms); difficulty functioning socially (ie, “negative” symptoms); and cognitive impairment. As many as 34% of patients with schizophrenia have treatment-resistant schizophrenia, defined as continuing symptoms despite at least 2 trials of appropriate antipsychotic treatment, and most people do not recover from it. Patients with... |
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HIV Snippets " A Podcast Series: Optimizing Care in HIV Treatment and Prevention
Antiretroviral therapy (ART) for treating HIV has improved dramatically over the past decade. This progress has yielded more treatment choices for clinicians and patients but also adds greater complexity to the already-diverse field of HIV treatment. In this CE activity, participants will listen to expert faculty in a series of 4 podcasts. The faculty will explore various aspects of HIV management, including geographic disparities in pre-exposure prophylaxis (PrEP) implementation, use of 3-dru... |
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Navigating the Evolving Treatment Landscape of Renal Cell Carcinoma to Ensure Equitable Access to Quality Care
Target Audience
This activity is designed specifically for oncologists, advanced practice providers, and other members of the healthcare team who serve patients from rural and underserved communities.
Program Overview
Therapeutic options for metastatic renal cell carcinoma (RCC) have expanded over the last decade and now include targeted therapies as well as immunotherapies. However, workforce shortages, low rates of recruitment into clinical trials, racial and socioeconomic inequities, a... |
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Right Treatment, Right Patient: Evidence-Based Approaches to the Treatment of Moderate-to-Severe Atopic Dermatitis Snippet 2: Currently Available Oral Therapies for Moderate-to-Severe Atopic Dermatiti
Target Audience
This activity is designed to meet the educational needs of dermatology and allergy physicians, nurse practitioners, PAs, and nurses who care for patients with moderate-to-severe atopic dermatitis.
Program Overview
This activity features a case presentation, a brief overview of currently available oral therapies, and insights from expert faculty.
Learning Objectives
After completing this activity, the participant should be better able to::
Identify the biologic prope... |
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Applying Guidelines and Latest Evidence to the Management of Moderate‐to‐Severe Asthma in Children and Adults
Target Audience
The educational design of this activity addresses the needs of pulmonologists, allergists/immunologists, NPs and PAs, and other clinicians involved in the management of patients with moderate‐to‐severe asthma.
Program Overview
Patients with asthma and underlying comorbidities require personalized treatment to achieve asthma control. Children with asthma have an especially high burden of symptoms, and are at risk of impaired lung development if asthma control cannot be ... |
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Intensive Review of Internal Medicine - IN PERSON or LIVE STREAMING
The Acclaimed Clinical Update and Board Review
With more than 150 lectures, case discussions, and board preparation sessions, this CME program is one of the most comprehensive reviews of internal medicine offered by the clinical faculty of Harvard Medical School.
It offers accelerated learning:
- For clinicians seeking a practical and comprehensive review that ensures you are up to date across all major fields of internal medicine:
• Newer options for diagnosis: what to choose, w... |
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Hot Topics in Blood-based Cancer Screening: Key Information on Multi-Cancer Early Detection from 2023 Spring Oncology Meetings
Early detection of cancer is essential to reducing the significant burdens associated with it. When cancer is detected at earlier stages, treatments can be initiated sooner, resulting in improved outcomes, reduced morbidity and mortality, and better quality of life. While the implementation of current screening guidelines has resulted in an overall reduction in cancer deaths, only 25% of cancers are diagnosed using traditional screening modalities, leaving much room for improvement. Blood-base... |
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Diabetes Comorbidities and Complications - LIVE STREAMING
This comprehensive course, which is among the highest-rated Harvard Medical School CME courses, provides education and updates to optimize your care of patients with diabetes and these conditions:
• Obesity
• Cardiovascular Disease
• Heart Failure
• Coronary Artery Disease
• Cerebrovascular Disease
• Hypertension
• Hyperglycemia
• Hypoglycemia
• Dyslipidemia
• Metabolic-Associated Fatty Liver Disease
• Chronic Kidney Disease
Sessions are led by experts in thes... |
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Autism Movement Therapy
Autism Movement Therapy® is an emerging therapy that combines movement and music with positive behavior support strategies to assist individuals with Autism Spectrum Disorder (ASD) in meeting and achieving their speech and language, social and academic goals. Its purpose is to connect left and right hemisphere brain functioning by combining patterning, visual movement calculation, audile receptive processing, rhythm and sequencing into a “whole brain” cognitive thinking approach that can ... |
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How Temperamental Differences Affect Young Children
Temperament plays a significant role in a child’s development, experience, relationships, and behaviors. Children often need supportive intervention to allow them to function in healthy ways and reach their potential. This video course will include a discussion of normal early childhood development and the range of normal functioning as it is impacted by temperament. The purpose of this course is to help participants understand the role that temperament plays in the trajectory of normal chil... |
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LET'S TALK: Tackling Complex Issues Regarding SM-AHN Management A Monday Morning Joe Online Educational Activity
Systemic mastocytosis (SM) is a group of rare disorders characterized by the accumulation of mast cells in internal tissues and organs. The pathogenesis of SM is linked to a characteristic exon 17 D816V mutation of the KIT gene. Systemic mastocytosis with associated hematologic neoplasms (SM-AHN) is an advanced subtype of SM that is associated with a shortened median survival time. Recent advances in the SM therapeutic landscape have led to the development of KIT-targeted treatment options; ho... |
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Case Studies in HIV Prevention and Treatment of Persons Who Use Drugs
Educational Need:
Prevention of HIV in individuals with substance use disorder (SUD) is vitally important from a public health perspective. People with SUD are significantly more vulnerable to contracting HIV, attributable to behaviors such as sharing needles and injection equipment, engaging in condomless sex, and impaired judgement. Furthermore, substance use can negatively affect medication adherence and engagement in healthcare, making it more challenging to treat and manage HIV in this ... |
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Delivering Culturally Competent Care: Managing Type 2 Diabetes in Diverse Populations
This course presents practical advice for working cross-culturally. It allows participants to practice and improve their communication skills while managing typical clinical problems encountered in persons with type 2 diabetes.
Outcome Objectives:
As a result of completing this activity, the participant will be better able to:
- Recognize the differences between the terms "race," "ethnicity," and "culture."
- Employ the Ask, Share, Compare, Negotiate Model with patients in the office... |
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Expanding the Benefit of Quality Improvement Programs: Sustainable Solutions to Achieve Therapeutic Goals for Patients with Myelofibrosis
Achieve measurable changes to improve your patients’ outcomes with this simple, systematic approach for quality improvement for application at any practice setting. Complete an assessment to understand where your practice’s performance falls relative to identified goals, which guides development of personalized action items. Access the framework and tools you need to measure your understanding. |
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Case Studies in HIV Resistance Testing and Treatment " Experienced Patients
Educational Need:
Through a series of patient cases, participants will explore the complexities of managing HIV infection in patients who have been treated with multiple different HIV regimens. Participants will engage in real-life case studies that will provide valuable insight into the intricacies of HIV treatment and resistance testing. Our faculty educators will discuss commonly encountered challenges faced by the care team and their treatment-experienced patients with HIV and offer real... |
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Unusual Paraphilias
A paraphilia involves stimulating sexual arousal in someone by an object or fantasy that for most people is commonplace and not sexually related, either directly or symbolically. What you will learn in this course is that there is a clear continuum of unusualness for paraphilias. There are some familiar ones and there are also very many paraphilias reported in the clinical literature which are indeed extremely unusual. This course will include discussions of the eight standard Paraphilic Disor... |
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Biology of Aging: Research Today for a Healthier Tomorrow
What is aging? Can we live long and live well—and are they the same thing? Is aging in our genes? How does our metabolism relate to aging? Can your immune system still defend you as you age? Since the National Institute on Aging was established in 1974, scientists asking just such questions have learned a great deal about the processes associated with the biology of aging. Technology today supports research that years ago would have seemed possible only in a science fiction novel. This cours... |
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Unusual Psychosexual Syndromes, Part 1: Koro, Autoerotic Asphyxia, and Necrophilia
This course presents three of the most unusual human sexual behavior disorders. Each syndrome is a relatively rare, yet extraordinarily intriguing pattern of behavior. These men and women have fashioned highly unorthodox means of gratifying their basic needs for love and attention. These syndromes are typically ignored or receive only mere mentions in most abnormal psychology textbooks. Yet, these individuals could very well appear in mental health professionals’ practices as inpatients or o... |
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Helping Your Young Client Persevere in the Face of Learning Differences
Clinicians and teachers working with students struggling at grade level are committed to raising their students’ achievement potential by creating opportunities to learn. In order to accomplish this, they need to learn new techniques that can help encourage discouraged students – particularly those who have different ways of learning – by supporting and motivating them without enabling self-defeating habits. This course will provide new strategies and techniques for helping students mini... |
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The Use of Humor in Therapy
Should therapists and counselors use humor as a therapeutic technique? If so, should they be formally trained in those procedures before their implementation? This course will review the risks and benefits of using humor in therapy and the relevant historical controversies of this proposal. The paucity of rigorous empirical research on the effectiveness of this form of clinical intervention is exceeded only by the absence of any training for those practitioners interested in applying humor tec... |
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Conquering Lab Interpretation (eLearning)
No matter what your area of expertise, no field in medicine spends enough time training you for lab interpretation. Join us as we conquer the interpretation of lab findings to help you gain the clues you need to provide better care to your patients. What we understand, we can then use to set up the plan of the day, to progress the patient towards good outcomes and to predict the next step in the treatment goal. Data collection and understanding are important steps in the development of critica... |