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Current Standards and New Directions in the Treatment of Acquired Thrombotic Thrombocytopenic Purpura
STATEMENT OF NEED
Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening thrombotic microangiopathy with a rapid onset and progression and a mortality rate of 10% to 20% with prompt treatment. Onset of aTTP is characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, and a constellation of associated symptoms including hemorrhage, neurologic and renal manifestations, cardiac abnormalities, and mesenteric ischemia (Joly et al, 2017). Survivors of f... |
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EGPA Expert Exchange " A Podcast Series on Eosinophilic Granulomatosis With Polyangiitis
Eosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg-Strauss syndrome, is a rare form of vasculitis that primarily affects the small blood vessels. Individuals diagnosed with EGPA commonly have a history of asthma and/or allergies. Eosinophilic inflammation associated with EGPA can lead to injury in multiple organ systems, including the sinuses, lungs, gastrointestinal system, heart, nervous system, and kidneys. Accurate diagnosis and treatment are critical to minimize g... |
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A Breath of Fresh Air: Novel Treatments That Address the Inflammatory Component of Non-Cystic Fibrosis Bronchiectasis
Non-cystic fibrosis bronchiectasis (NCFBE) is a heterogenous and increasingly prevalent chronic pulmonary disease that is associated with high morbidity and mortality. It is characterized by irreversibly damaged and dilated bronchi, and has a broad spectrum of clinical presentations, ranging from asymptomatic radiological changes detected incidentally to chronic sputum production and recurrent exacerbations. There are numerous etiologies that can induce or contribute to the pathophysiological ... |
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The Pharmacist’s Role in Managing Patients with Worsening Heart Failure
Pharmacists play a vital role in the management of patients with heart failure (HF). Navigate through this interactive self-directed, pharmacist-targeted activity designed to optimize your decision-making to apply the most recent clinical trial data and guidance seen in real-world HF practice, particularly in patients with worsening HF and after recent HF hospitalization. Expert perspectives and insights cover guideline-directed medical therapy (GDMT) implementation and additional adjustment t... |
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Pathways for Optimal Sequencing, Rapid Initiation, and Titration of Therapy in Patients with Heart Failure
Many patients with heart failure (HF) do not receive foundational treatment although these therapies reduce morbidity and mortality risks. The initiation and optimization of guideline-directed medical therapies (GDMT) can be challenging, but clinical practice guidelines and algorithms are available to assist.
Navigate through this interactive self-directed CME activity to apply the most recent clinical trial data and guidance to patient-specific factors seen in real-world practice. Expert p... |
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Developing Optimal Strategies for Reducing Morbidity in Patients with Non-Cystic Fibrosis Bronchiectasis
This case-based morbidity and mortality review (MMR) assesses the negative implications of suboptimal therapeutic management for patients with non-cystic fibrosis bronchiectasis. Cases and expert discussion focus on ensuring a prompt and accurate diagnosis of bronchiectasis, understanding the benefits of high frequency chest wall oscillation (HFCWO), and identifying patients who can benefit from HFCWO. |
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Rheumatology 101 for the Primary Care Clinician
The Pacific Northwest is experiencing a critical shortage of rheumatologists. Despite efforts from multiple organizations, including the American College of Rheumatology, The Arthritis Foundation, The University of Washington, and Virginia Mason Medical Center, Washington State continues to rank near the bottom for access issues. In a May 2022 interview, Washington Rheumatology Alliance (WRA) President Jeff Peterson, MD noted with concern that rural patients are particularly underserved, with ... |
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Hot Topics in Blood-based Cancer Screening: Key Information on Multi-Cancer Early Detection from 2023 Spring Oncology Meetings
Early detection of cancer is essential to reducing the significant burdens associated with it. When cancer is detected at earlier stages, treatments can be initiated sooner, resulting in improved outcomes, reduced morbidity and mortality, and better quality of life. While the implementation of current screening guidelines has resulted in an overall reduction in cancer deaths, only 25% of cancers are diagnosed using traditional screening modalities, leaving much room for improvement. Blood-base... |
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Multidisciplinary Strategies to Prevent Hospitalization in Patients with Worsening Heart Failure
Despite guideline-directed medical therapy, many patients with heart failure (HF) with reduced ejection fraction continue to experience worsening HF and hospitalizations. As such, it is incumbent upon clinicians to improve familiarity and competence with available therapies and clinical trial data that may guide patient selection to individualize and optimize therapy for patients with HF. In this interactive infographic, clinicians can access real-world strategies and expert insights to improv... |
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It Takes a Village: Working Together to Reduce Racial Inequities in Maternal Morbidity and Mortality
Maternal morbidity and mortality rates are unacceptably high in the United States (US). In fact, Black women are two to three times more likely to die from pregnancy-related causes than white women, prompting the US Department of Health and Human Services to state that maternal deaths are a public health crisis. What can you do to address these inequities in maternal health? Two experts in this field will discuss the latest data on maternal deaths and frame practical and supportive strategies ... |
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Case Studies in HIV Prevention and Treatment of Persons Who Use Drugs
Educational Need:
Prevention of HIV in individuals with substance use disorder (SUD) is vitally important from a public health perspective. People with SUD are significantly more vulnerable to contracting HIV, attributable to behaviors such as sharing needles and injection equipment, engaging in condomless sex, and impaired judgement. Furthermore, substance use can negatively affect medication adherence and engagement in healthcare, making it more challenging to treat and manage HIV in this ... |
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Nursing Management of Tumor Lysis Syndrome
STATEMENT OF NEED
Tumor lysis syndrome (TLS) is an oncological emergency that occurs when massive tumor lysis causes the rapid release of intracellular components into the bloodstream. Electrolyte imbalances characterized by hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia may be severe enough to cause acute renal failure, cardiac arrhythmias, seizures, and even death. Current advances in cancer therapies can increase the incidence of TLS; therefore, identification of patien... |
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Tropical Charms of the Seychelles: Hot Topics in Medical, Dental & Public Health Issues
Discover paradise as you sail the Indian Ocean for 7 nights on a luxury Seychelles yacht cruise with PES! Nestled over 900 miles from mainland Africa in the topaz waters of the Indian Ocean, lies the blissful Seychelles Islands. Brimming with incredible landscapes, rare wildlife, and a vibrant atmosphere, a Seychelles cruise will introduce you to East Africa’s archipelago of utopia, all while enjoying the all-inclusive, 100-guest Emerald Azzurra.
Hot Topics in Medical, Dental & Public... |
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Eating Disorder Toolkit
Eating Disorder Toolkit is a 1-hour online continuing education (CE/CEU) course that provides an overview of the current research regarding prevalence, treatment, and the role of the RDN in the care of eating disorders.
Eating disorders (ED) are severe psychiatric disorders that are associated with increased levels of social, psychological, and physical impairment as well as high levels of morbidity and mortality. This toolkit will address the three main eating disorders as listed in the Di... |
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Cultural & Behavioral Health Disparities Amid COVID-19
Cultural & Behavioral Health Disparities Amid COVID-19 is a 4-hour online continuing education (CE/CEU) course that examines COVID-19 and other mental and behavioral health disparities among racial and ethnic minority populations.
We address social determinants of health and their influence on mental and behavioral health outcomes for COVID-19. Research findings are presented to assist with the knowledge component of racial and ethnocultural responsiveness.
We examine the mental and beha... |
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