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Major Depressive Disorder & Postpartum Depression: Targeting the GABA Deficit
Major depressive disorder (MDD), perinatal depression, and postpartum depression (PPD) are increasingly prevalent conditions that carry an extremely high disease burden. Underdiagnosis and undertreatment of major depressive episodes have led to significant unmet needs for these patient populations. Success of treatment with traditional antidepressants that target monoaminergic deficiencies and imbalances is limited by non- or incomplete therapeutic response as well as delayed onset of action. ... |