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Exploring Novel Treatments for Rett Syndrome

STATEMENT OF NEED Rett syndrome is a rare, debilitating neurodevelopmental disorder almost always associated with a spontaneous mutation in the methyl-CpG-binding protein 2 (MECP2) gene on the X-chromosome. Affected individuals experience loss of purposeful hand skills, abnormalities in gait, loss of spoken language, and stereotypic hand movements, with more severe manifestations including seizures, autistic features, autonomic nervous system dysfunction, breathing abnormalities, sleep dist...
i3 Health

Nursing Management of Tumor Lysis Syndrome

STATEMENT OF NEED Tumor lysis syndrome (TLS) is an oncological emergency that occurs when massive tumor lysis causes the rapid release of intracellular components into the bloodstream. Electrolyte imbalances characterized by hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia may be severe enough to cause acute renal failure, cardiac arrhythmias, seizures, and even death. Current advances in cancer therapies can increase the incidence of TLS; therefore, identification of patien...
i3 Health

Neurological Emergencies - LIVE STREAMING

Evaluation. Detection. Diagnosis. Management. In Emergency, Outpatient, and Inpatient Settings Neurological Emergencies will be held online this year, using live streaming, electronic Q&A, and other remote learning technologies. OVERVIEW This special program provides new strategies, updates, best practices, and practical tips for: • The WORKUP of common neurological complaints and high-risk conditions • RAPID DETECTION of a neurological emergency and EARLY ACTIONS to opt...
Harvard Medical School

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