Applying Evolving Targeted Therapy in Acute Myeloid Leukemia
Acute Myeloid Leukemia (AML) is a biologically heterogeneous hematologic malignant neoplasm with a 5-year survival rate of 30%. Hematologist, Brian Jonas, MD, PhD, UC Davis Comprehensive Cancer, discusses standard induction, consolidation, and maintenance therapy, as well as factors to consider in individualizing intensive therapy in fit and unfit patients. Dr. Jonas presents safety and efficacy...
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Clinical Questions in Cardiology: Using Glucagon-like Peptite-1 Receptor Agonists
The glucagon-like peptide-1 receptor agonist (GLP-1RA) class of medications has become an important option for treating patients with type 2 diabetes mellitus (T2D). Cardiovascular outcome trials also show that selected GLP-1RAs exert beneficial cardiovascular benefits in patients with and without T2D. In this activity, case studies commonly encountered in cardiology practice are utilized to pro...
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Contemporary Issues in the Management of Patients With Primary Biliary Cholangitis: An Interprofessional Approach
An interprofessional faculty of gastroenterology clinicians discuss real-world issues in managing patients with primary biliary cholangitis. Two mini-lectures serve as the foundation for understanding the diagnostic evaluation and risk factors of primary biliary cholangitis. Three cases foster a robust discussion, among the 5 faculty, of clinical decision-making around the roles, benefits, and l...
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Contemporary Management of Patients with Systemic Lupus Erythematosus: A Case-based Approac
This modular continuing education activity provides an update on the epidemiology, monitoring, and treatment of patients with systemic lupus erythematosus (SLE). Diane Kamen, MD, and Anca Askanase, MD, examine the current research on demographic groups with an increased risk of SLE and its severe complications, including lupus nephritis (LN). They also review the application of the most current...
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Managing Patients with Rheumatic Disorders in Primary Care
Rheumatic disorders are prevalent, yet their diagnosis and treatment in affected patients are frequently challenging, contributing to a considerable disease burden. Ensuring timely intervention is critical to slow disease progression and improve patient outcomes. However, various educational gaps impede primary care clinicians from effectively achieving these goals. This 0.75-hour text-based act...
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Optimizing Outcomes in ALS: Best Practices in Screening, Diagnosis, and Treatment
"Optimizing Outcomes in ALS: Best Practices in Screening, Diagnosis, and Treatment" is a modular continuing education series led by Dr. Richard Bedlack, a nationally recognized ALS expert. This self-navigation program focuses on amyotrophic lateral sclerosis (ALS), providing healthcare professionals with valuable insights and evidence-based strategies to enhance outcomes in ALS care. P...
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Prurigo Nodularis: Recognizing, Diagnosing and Treating a Rare but Debilitating Disease
Prurigo Nodularis is a rare, chronic skin disorder that causes substantial patient burden, but is often overlooked or misdiagnosed and, until recently, had no medications approved by the US Food and Drug Administration. The interprofessional faculty share their real-world perspectives on the diagnosis and treatment of patients with prurigo nodularis to reduce patient burden of disease and improv...
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The Importance of Early Recognition of Tay-Sachs and Sandhoff Disease
Faculty experts Jeanine Jarnes, PharmD, and Chester Whitley, MD, PhD, delve into the rare and difficult to diagnose GM2-gangliosidoses Tays-Sachs and Sandhoff diseases. Following a discussion of the etiology and pathophysiology of these diseases, the faculty use real-life cases to illustrate the various phenotypes of these conditions, as well as key presenting signs and symptoms. Diagnostic appr...
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Treatment Considerations in Cutaneous Melanoma: From Early Stage to Late/Advanced Stage
Jason J. Luke, MD, discusses the impact of evolving therapies on the disease burden, survival, and treatment tolerability for patients with cutaneous melanoma. Recent clinical trial results and guideline updates for both perioperative and metastatic cutaneous melanoma are reviewed. To provide patient-centric care, Dr. Luke shares his expert insights and recommendations for individualizing treatm...
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Understanding Cholesterol Guidelines and Implementing Non-statins in High-Risk Populations: Paired Conversations and Case Vignettes
An interprofessional faculty of primary care and specialty clinicians discuss real-world issues in managing patients with complex and challenging dyslipidemia, including elevated lipoprotein a (Lp(a)). Several paired conversations serve as the foundation for discussions related to recent cholesterol guidelines, patient risk stratification, and recommended goals for patients at risk of atheroscle...
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