Overview
Clinical Case Challenges: Strategies to Optimize Primary Immunodeficiency Management
Clinical Case Challenges in PI
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In this activity, Dr. Chong reviews two PI clinical cases and explores strategies that lead to earlier diagnosis and appropriate treatment modalities with a focus on varied disease presentations, common complications, improved drug delivery methodologies, and shared decision making.
This activity is intended for immunologists, allergists, primary care providers, and other clinicians involved in the diagnosis and management of patients with primary immunodeficiencies.
Primary care providers, internists, and other general practitioners may be the first to see a patient with PI and require a level of awareness. Yet, a survey issued by the American Academy of Allergy Asthma and Immunology and the Immune Deficiency Foundation found that only 4% of primary care practitioners were aware that guidelines existed for the diagnosis and management of primary immunodeficiency. Because symptoms can overlap with many other conditions and/or diseases, it is also important that either an allergist or an immunologist evaluate the patient to screen for PI.
The management of PI patients on IgG therapy is extremely complex, and there are various immunoglobulin formulations/delivery systems with different risk/benefit profiles that must be individualized for diverse PI patients. Thus, this activity endeavors to increase the knowledge and competence of PCPs, internists, and other practitioners regarding the diagnosis and treatment of PI in an effort to enhance patient outcomes.
Upon completion of this activity, participants will be able to:
• Describe clinical strategies for optimizing interdisciplinary care models in PI therapy management.
• Evaluate clinical protocols for screening patients for PI, identifying PI causes, and targeting IgG therapy across patient populations.
• Compare and contrast novel immunoglobulin formulations/delivery systems, their risk/benefit profiles, and which patient populations novel formulations may benefit.
• Examine emerging research data on PI genotypes and phenotypes/other emerging diagnostic strategies, and how the data intersects with novel therapies, existing therapies, and targeted treatment strategies.
• Discuss optimal clinical communication strategies and related shared decision-making tactics for providing optimal management of PI patients.
• Describe clinical strategies for optimizing interdisciplinary care models in PI therapy management.
• Evaluate clinical protocols for screening patients for PI, identifying PI causes, and targeting IgG therapy across patient populations.
• Compare and contrast novel immunoglobulin formulations/delivery systems, their risk/benefit profiles, and which patient populations novel formulations may benefit.
• Examine emerging research data on PI genotypes and phenotypes/other emerging diagnostic strategies, and how the data intersects with novel therapies, existing therapies, and targeted treatment strategies.
• Discuss optimal clinical communication strategies and related shared decision-making tactics for providing optimal management of PI patients.
Sponsored by the Academy for Continued Healthcare Learning (ACHL).
Supported by an educational grant from Grifols.
Hey Jin Chong, MD, PhD
Division Director of Pediatric Allergy & Immunology
Associate Professor of Pediatrics
Children's Hospital of Pittsburgh
University of Pittsburgh Medical Center
Pittsburgh, PA
Division Director of Pediatric Allergy & Immunology
Associate Professor of Pediatrics
Children's Hospital of Pittsburgh
University of Pittsburgh Medical Center
Pittsburgh, PA
The Academy for Continued Healthcare Learning (ACHL) requires that the faculty participating in a CME activity disclose all affiliations or other financial relationships (1) with the manufacturers of any commercial product(s) and/or provider(s) of commercial services discussed in an educational presentation and (2) with any commercial supporters of the activity. All conflicts of interest have been resolved prior to this CME activity.
The following financial relationships have been provided:
Hey Jin Chong, MD, PhD
Advisory Board: Horizon Pharma
Discussion of Off-Label, Investigational, or Experimental Drug/Device Use: None
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This activity will take approximately 30 minutes to complete. To receive credit, participants are required to complete the pretest, view the online activity and complete the posttest and evaluation. To receive credit, 80% must be achieved on the posttest. A certificate will be immediately available. There is no fee to participate in the activity or for the generation of the certificate.
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