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Intravitreal aflibercept injection vs sham as prophylaxis against conversion to exudative age-related macular degeneration in high-risk eyes: a randomized clinical trial

By: Brian K. Do, MD

This course has expired. You can still review the content but course credit is no longer available.

Supplement Credits: 0.25

May 2021: VBS Literature Update

Heier JS, Brown DM, Shah SP, et al. Intravitreal aflibercept injection vs sham as prophylaxis against conversion to exudative age-related macular degeneration in high-risk eyes: a randomized clinical trial. JAMA Ophthalmol. 2021 Mar 18:e210221. doi: 10.1001/jamaophthalmol.2021.0221. Epub ahead of print. PMID: 33734306; PMCID: PMC7974836.

Abstracted by Brian K. Do, MD

Expiration Date: Wednesday, June 1, 2022
Release Date: June 1, 2021

Learning Objectives

Upon completion of this activity, the participant should be able to:

  • Identify potential reasons for the effect of aflibercept on rates of conversion to exudative AMD in high-risk eyes.
  • Discuss possible therapeutic targets / goals in the pharmacologic prevention of conversion to exudative AMD.

Accreditation and Designation Statement

Provided by Evolve Medical Education

Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Evolve Medical Education, LLC and Vit Buckle Society.  Evolve Medical Education; LLC is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statement
Evolve Medical Education LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participation Method

In order to obtain credit, proceed through the program, complete the post-test, evaluation and submit for credit.

Course Viewing Requirements

Supported Browsers:
Internet Explorer 11 for Windows
Edge (recent versions; Chromium-based) for Windows
Google Chrome (recent versions) for Windows, Mac OS, iOS, Android, or Linux
Mozilla Firefox (recent versions) for Windows, Mac OS, iOS, Android, or Linux
Safari (recent versions) for Mac OSX, or iOS

Hardware Requirements:
4GB+ RAM
Recommended internet speed 5Mbps+

Faculty and Disclosures

Brian K. Do, MD

The Retina Group of Washington
Washington, DC

DISCLOSURE POLICY
It is the policy of Evolve that faculty and other individuals who are in the position to control the content of this activity disclose any real or apparent conflicts of interest relating to the topics of this educational activity. Evolve has full policies in place that will identify and mitigate all conflicts of interest prior to this educational activity.

The following faculty/staff members have the following financial relationships with commercial interests:

Brian K. Do, MD, has had a financial agreement or affiliation during the past year with the following commercial interests in the form of Consultant: Allergan/Abbvie, Alimera, Bausch & Lomb; Speakers Bureau: Allergan/Abbvie

The Evolve staff and planners have no financial relationships with commercial interests.
Nisha Mukherjee, MD, peer reviewer, has no financial relationships with commercial interests.

Disclaimer

OFF-LABEL STATEMENT
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The opinions expressed in the educational activity are those of the faculty. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

DISCLAIMER
The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of Evolve 

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