EGPA Expert Exchange – A Podcast Series on Eosinophilic Granulomatosis With Polyangiitis

Overview

Provider Statement

This continuing education activity is provided by 

Support Statement

This educational activity is supported by an educational grant from GSK.

Activity Description

Eosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg-Strauss syndrome, is a rare form of vasculitis that primarily affects the small blood vessels. Individuals diagnosed with EGPA commonly have a history of asthma and/or allergies. Eosinophilic inflammation associated with EGPA can lead to injury in multiple organ systems, including the sinuses, lungs, gastrointestinal system, heart, nervous system, and kidneys. Accurate diagnosis and treatment are critical to minimize glucocorticoid exposure, disease burden, and mortality. Education can provide clinicians with the latest information regarding optimal diagnostic and management strategies, including targeted steroid-sparing therapy. In this podcast series, experts will provide guidance on differentiating EGPA from related vasculitides and hypereosinophilic conditions, highlight recent clinical data, and discuss evidence-based recommendations to improve patient outcomes.

Target Audience

The intended audience for this activity is allergists, immunologists, pulmonologists, rheumatologists, and other healthcare professionals involved in the management of patients with EGPA.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:

• Outline available immunopathology evidence and various clinical presentations of EGPA, as well as the implications for diagnosis.
• Summarize the burdens and comorbidities associated with EGPA that negatively affect patients’ quality of life.
• Examine different diagnostic approaches for their ability to distinguish EGPA from other vasculitides or eosinophilic conditions.
• Describe the use of immunosuppressants and corticosteroids for the induction and maintenance of EGPA remission, including limitations.
• Apply evidence-based recommendations and the latest clinical evidence to improve the management of patients with EGPA.

Activity Chair

Leonard H. Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine
Case Western Reserve University
R.J. Fasenmyer Chair of Clinical Immunology
Cleveland Clinic
Cleveland, OH

Faculty

Adam J. Brown, MD
Center for Vasculitis Care and Research
Department of Rheumatic and Immunologic Diseases
Orthopaedic and Rheumatologic Institute
Cleveland Clinic
Cleveland, OH

Anisha B. Dua, MD, MPH
Associate Professor, Fellowship Program Director
Director of the Vasculitis Center
Northwestern University Feinberg School of Medicine
Chicago, IL

Michael Putman, MD/MSci
Assistant Professor of Medicine
Associate Program Director, Rheumatology
Associate Program Director, Internal Medicine
Medical Director, Vasculitis Program
Medical College of Wisconsin
Milwaukee, WI

Planner/Reviewer

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP

Accreditation

In support of improving patient care, Vindico Medical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, May 31, 2023, to May 30, 2024.

How to Participate in This Activity and Obtain CE Credit

To participate in this activity, you must read the objectives, answer the polling and pretest questions, listen to the podcasts, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 5 of the 7 posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ certificate.

Disclosures

Vindico Medical Education adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a continuing education activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Relationship information is accurate at the time of content development.

Activity Chair and Faculty report the following relevant financial relationship(s)

Adam J. Brown, MD
Consultant: Amgen

Leonard H. Calabrese, DO
Consultant: Genentech, GSK, Regeneron, Sanofi-Genzyme
Speaker Contracted by Ineligible Company: AstraZeneca, Sanofi-Genzyme, Regeneron

Anisha B. Dua, MD, MPH
Advisor: Novartis
Consultant: GSK, Novartis, Sanofi

Michael Putman, MD/MSci
Consultant: Novartis
Independent Research Contractor: AstraZenenca

Planner/Reviewer reports the following relevant financial relationship(s)

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.

Vindico Medical Education staff report the following relevant financial relationship(s)

No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

ADA Compliance

In compliance with the Americans with Disabilities Act of 1990, we will make all reasonable efforts to accommodate persons with disabilities. A text-based transcript of this podcast is available upon request. Requests should include the web activity title and emailed to CME@VindicoCME.com. Requests will be honored within 3 to 5 business days.

Unlabeled and Investigational Usage

The audience is advised that this continuing education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2023 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any Vindico Medical Education continuing education activity does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the FDA. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CE Questions?

Contact us at cme@vindicoCME.com