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Exploring Novel Treatments for Rett Syndrome

STATEMENT OF NEED Rett syndrome is a rare, debilitating neurodevelopmental disorder almost always associated with a spontaneous mutation in the methyl-CpG-binding protein 2 (MECP2) gene on the X-chromosome. Affected individuals experience loss of purposeful hand skills, abnormalities in gait, loss of spoken language, and stereotypic hand movements, with more severe manifestations including seizures, autistic features, autonomic nervous system dysfunction, breathing abnormalities, sleep dist...
i3 Health

Clinical Questions in Cardiology: Using Glucagon-like Peptite-1 Receptor Agonists

The glucagon-like peptide-1 receptor agonist (GLP-1RA) class of medications has become an important option for treating patients with type 2 diabetes mellitus (T2D). Cardiovascular outcome trials also show that selected GLP-1RAs exert beneficial cardiovascular benefits in patients with and without T2D. In this activity, case studies commonly encountered in cardiology practice are utilized to prompt reflection on opportunities for reducing cardiovascular risk. Drawing on seminal research and th...
Annenberg Center for Health Sciences at Eisenhower

Nurses Light the Path: Empowering Patients to Improve Breast Cancer Screening and Clinical Trial Representation

Target Audience The primary target audience for this activity is Oncology Nursing Professionals (APRN, NP, RN). Program Overview For women with breast cancer and those at risk, disparities in screening and clinical-trial enrollment exist, particularly among racial and ethnic minority populations. Awareness of these disparities can ensure timely screening practices and help address patient fears and concerns regarding clinical trials that inhibit diverse representation in research. Younger...
Partners for Advancing Clinical Education (PACE) and PlatformQ Health Education, LLC, in collaboration with Black Nurses Rock.

Exploring New Treatment Advances for Acid Sphingomyelinase Deficiency in Adults

STATEMENT OF NEED Acid sphingomyelinase deficiency (ASMD) is a rare, hereditary lysosomal storage disease with multisystemic manifestations, including splenomegaly, hepatomegaly, interstitial lung disease, dyslipidemia, bone marrow and lymph node involvement, and sometimes neurological and peripheral nerve involvement. While the most severe form of ASMD, infantile neurovisceral ASMD, results in death in early childhood, chronic forms of ASMD have more prolonged survival but are associated w...
i3 Health

Current Standards and New Directions in the Treatment of Acquired Thrombotic Thrombocytopenic Purpura

STATEMENT OF NEED Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening thrombotic microangiopathy with a rapid onset and progression and a mortality rate of 10% to 20% with prompt treatment. Onset of aTTP is characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, and a constellation of associated symptoms including hemorrhage, neurologic and renal manifestations, cardiac abnormalities, and mesenteric ischemia (Joly et al, 2017). Survivors of f...
i3 Health

Supporting Neurodevelopment With Brain-Building Nutrition

The brain is one of the fastest growing organs in infants; by the time infants reach 2 years of age, the brain has nearly doubled in size. During this period of time, neurons proliferate, synapses form, and nerve fibers are myelinated"all processes that require support with optimal nutrition. This material reviews the latest learnings on the ways in which nutrition can influence neurodevelopment. Human milk is rich in key lipids for neurodevelopment, which are encapsulated by the milk fat...
Annenberg Center for Health Sciences

Ethics for Occupational Therapists

Ethics for Occupational Therapists is a text-based, 3-hour online continuing education (CE/CEU) course that teaches OTs how to address ethical and moral dilemmas in practice. Ethical and moral issues pervade our lives and healthcare professionals are constantly confronted with a variety of ethical and moral dilemmas. Decisions can have long-range effects professionally and personally, not only for the healthcare professional, but for patients, clients, healthcare entities, and society. Why ...
Professional Development Resources

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