Activity Provided By:

ACHL

Targeting the JAK/STAT Pathway in Immune-mediated Inflammatory Diseases: Current and Future Directions

Overview / Abstract:	A Clinical Commentary features a video-based digital classroom which includes didactic clinical reviews, faculty discussions and an augmented reality MOA animation. This educational activity will provide clinicians with clinical data and expert opinions to aid them in providing the best possible care to their patients with inflammatory medicated diseases, Rheumatoid arthritis(RA) and inflammatory bowel disease (IBD). RA and iIBD are chronic, systemic, autoimmune disorders characterized by inflammatory processes. There are numerous classes of therapies available to treat RA and IBD, and some patients achieve low disease activity or remission, yet a proportion of patients exhibits an inadequate response and/or discontinues therapy due to tolerability. As such, investigations into new targets and therapies, such as the janus kinase (JAK) inhibitors, continue. The introduction of JAK inhibitors further contributes to a growing armamentarium of therapies for these immune-mediated inflammatory diseases. Evolving strategies for employing the JAK inhibitors present a decision-making challenge to clinicians who treat these patients.
Expiration	Apr 13, 2019
Discipline(s)	Physician CME
Format	Online, Webinar / Webcast / Video
Credits / Hours	The Academy for Continued Healthcare Learning designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Accreditation	The Academy for Continued Healthcare Learning is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Is This Activity Certified for "Live" Credit?	YES
Presenters / Authors / Faculty	Russell Cohen, MD (Moderator) Professor of Medicine Directory, Inflammatory Bowel Disease Center Co-Director, Advanced IBD Fellowship Program University of Chicago Medical Center Chicago, Illinois William Rigby, MD (Faculty) Professor of Medicine, Microbiology and Immunology Division of Rheumatology Vice Chairman, Academic Affairs Department of Medicine Dartmouth Medical School Dartmouth-Hitchcock Medical Center Lebanon, New Hampshire Joel Pekow, MD (Faculty) Assistant Professor of Medicine Section of Gastroenterology, Hepatology and Nutrition University of Chicago Medicine and Biological Sciences Chicago, Illinois
Activity Specialities / Related Topics	Gastroenterology / GI, Rheumatology / Arthritis
Sponsors / Supporters / Grant Providers	Supported by an educational grant from Gilead Sciences, Inc.
Keywords / Search Terms	ACHL CE, Continuing Education, CME/CE, Rheumatology, Gastroenterology, Gilead Sciences, Inc., JAK/STAT signaling pathway, JAK inhibitors, JAK, JAK1, RA, Rheumatoid Arthritis, IBD, Inflammatory Bowel Disease, inflammation, gastrointestinal tract, Chron’s disease, ulcerative colitis, UC, proinflammatory cytokines, emerging JAK inhibitors, Russell Cohen, MD, William Rigby, MD, Joel Pekow, MD, filgotinib, tofacitinib, upadacitinib Free CE CME Live CE CME

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