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Appropriate Antibiotic Selection in Multidrug-Resistant Pneumonia with Gram-Negative Bacteria: Identifying Pathogens and Related Antimicrobial Stewardship

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Overview / Abstract:

Filmed at a prominent infectious disease meeting in October 2018, experts James Lewis, PharmD and James McKinnell, MD offer a lively discussion and clinical analysis of current optimal management of multidrug-resistant Gram-negative pseudomonas-based pneumonia infections in the context of a complex patient case.

The purpose of this activity is to update physicians and pharmacists that may come in clinical contact with serious, treatment-refractory bacterial infections such as Gram-negative infections with the latest clinical evidence, practice guidelines, and antimicrobial stewardship protocols for providing optimal treatment.

Upon completion of this activity, participants will be able to:
Demonstrate an understanding of the molecular epidemiology of antibiotic resistance in bacterial pathogens.
Summarize the salient features and critical differences between novel antibiotics for use against Gram-negative pathogens.
Describe clinical strategies to optimize antimicrobial therapy to ensure effectiveness of antibiotics and reduce resistance.

This activity is intended for ID specialists, hospitalists, pulmonologists, critical care specialists, internists, and other physicians, pharmacists, nurse practitioners, and physician assistants who care for patients at risk of serious infection.

Certified for physicians and pharmacists.


Nov 30, 2019


Nurse Practitioner , Nursing CNE, Pharmacy CPE, Physician CME, Physician Assistant CME, Radiology / RAD Tech CE


Online, Webinar / Webcast / Video

Credits / Hours




Is This Activity Certified for "Live" Credit?


Presenters / Authors / Faculty

James Lewis, II, PharmD, FIDSA
Infectious Disease Clinical Pharmacy Supervisor
Co-Director of Antibiotic Stewardship
Department of Pharmacy
Oregon Health & Science University
Portland, Oregon

James McKinnell, MD
Assistant Professor of Medicine
David Geffen School of Medicine
University of California, Los Angeles
Infectious Disease Clinical Outcome Research Unit
Los Angeles Biomedical Research Institute at Harbor-UCLA
Torrance, California

Activity Specialities / Related Topics

Acute Care, Antibiotics / Anti-Infectives, Contamination & Infection Control, Critical Care / Intensive Care, Emergency Medicine, Hospital-Acquired Infections, Infectious Disease, Pulmonary Medicine / COPD, Surgery, Urology

Sponsors / Supporters / Grant Providers

Supported by an educational grant from Merck & Company.

Keywords / Search Terms

ACHL Gram-negative; Gram-negative infections, HAPs; VAPs; Hospital-acquired pneumonias; Ventilator-associated pneumonias; cUTIs, antimicrobial stewardship, cephalosporins; IDSA/SHEA guidelines; pseudomonas; antibiotic resistance; resistant pathogens, combination therapy, combination antibiogram, antibiogram, clinical breakpoints, James Lewis, James McKinnell, Merck & Company, IDWeek, IDWeek 2018, IDWeek Symposium, infectious diseas Free CE CME Live CE CME

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