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The Rx Consultant

Cannabidiol (CBD)

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Overview / Abstract:

The popularity of medical marijuana (also known as medical
cannabis) continues to grow in the US. In 2018, over 3.5 million
patients were registered to use medical cannabis; an increase
from 2.6 million in March, 2016. As of January 2019, 33 states
and Washington D.C., have laws legalizing medical marijuana.
Ten states, Washington D.C., and Canada have legalized recreational
marijuana.2-4 In addition, a growing number of states
have laws specifically addressing the use of cannabidiol (CBD)
for medical, as well as nonmedical, purposes.

The use of Cannabis sativa by the Chinese – for its strength as
a fiber (in paper, bowstrings, rope, or clothing) and its medicinal
properties – has been documented as far back as 4000 years ago.
Hemp and marijuana are both plants in the Cannabis sativa family;
however, they differ in structure and active ingredients. The
most prevalent active ingredient in marijuana is tetrahydrocannabinol
(THC), known for its psychoactive effects. Cannabidiol
(CBD) is the second most prevalent active ingredient in marijuana
(among many other pharmacologically active cannabinoids)
and is the most prevalent active ingredient in hemp. Both THC
and CBD have pharmacological effects. However, unlike THC,
CBD does not have euphoric or intoxicating effects. A growing
body of research suggests that CBD may be beneficial for a range
of medical conditions including, but not limited to, anxiety,
movement disorders, pain, sleep disorders, and seizure disorders.
The FDA has approved CBD (Epidiolex®) for the treatment
of 2 rare childhood-onset epilepsy syndromes. The evidence for
CBD use in other conditions is sparse; it is derived mainly from
animal, in vitro, and small human trials. However, because of its
apparent lack of side effects in low to moderate doses, there is a
great interest in CBD as a natural supplement.

Hemp is used to produce a wide variety of products including
fiber, food ingredients, nutraceuticals, and body care
products, among others.10 Generally, CBD products can
be purchased in retail outlets (such as health food stores,
supermarkets, gas stations), medical marijuana dispensaries
(depending on the state), or online. People are
interested in using CBD, whether use is legal or not. It
may be an option for patients with conditions that have
not responded well to conventional medications, and
those with intolerance to these medications.
Patients are turning to medical professionals for guidance
on the potential uses of CBD products. This article
will provide health care professionals with a basic understanding
of CBD – the legal issues, evidence for use,
side effects, drug interactions, approaches to dosing, and
product availability.

Expiration

Apr 22, 2022

Discipline(s)

Nurse Practitioner , Pharmacy CPE

Format

Monograph

Cost

$6.95

Credits / Hours

1.5

Accreditation

ACPE

Presenters / Authors / Faculty

Deborah Berlekamp, PharmD, BCPS is an Assistant
Professor of Pharmacy Practice at The University of Findlay
College of Pharmacy in Findlay, Ohio. Her teaching focus
is in the areas of pharmacy law, sterile and non-sterile
compounding, and pain management.

Keywords / Search Terms

Continuing Education Network Inc. medical marijuana, CBD, CBD products, Epidiolex, medical cannabis, Cannabidiol, THC, tetrahydrocannabinol, marijuana dispensaries

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