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Optimizing Antibiotic Therapy to Treat Gram-negative Pathogens and Improve Outcomes in HAP/VAP

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Overview / Abstract:

George Karam, MD reviews a HAP/VAP patient case presented along with a faculty panel at MAD-ID 2019. Discussion topics include challenges with P. aeruginosa, ensuring effectiveness of antibiotics while reducing resistance, as well as new and emerging approaches to Gram-negative organisms.

The purpose of this activity is to provide clinicians who care for patients with serious infections with the latest data on antimicrobial stewardship, available and emerging antibiotics against Gram-negative pathogens, and the optimization of therapy to improve outcomes and reduce resistance.

Upon completion of this activity, participants will be able to:
• Summarize the burden of HAP/VAP and challenges associated with its management
• Outline patient and clinical factors that increase risks for resistant Gram-negative pathogens
• Describe strategies to optimize antimicrobial therapy to ensure effectiveness and reduce resistance


Jun 28, 2020


Nurse Practitioner , Nursing CNE, Pharmacy CPE, Physician CME, Physician Assistant CME, Respiratory Therapy CE


Online, Podcast, Webinar / Webcast / Video

Credits / Hours




Is This Activity Certified for "Live" Credit?


Presenters / Authors / Faculty

George H. Karam, MD
Paula Garvey Manship Chair of Medicine
Head of the LSUHSC Dept. of Internal Medicine
Louisiana State University
Baton Rouge, LA

Jason M. Pogue, PharmD, BCPS‐ID
Clinical Pharmacist, Infectious Diseases
Sinai‐Grace Hospital
Detroit Medical Center
Clinical Assistant Professor of Medicine
Wayne State University School of Medicine
Detroit, MI

Patricia (Trish) Simner, PhD, D(ABMM)
Director of Medical Bacteriology and Parasitology Laboratories
Associate Professor of Pathology
Johns Hopkins School of Medicine
Baltimore, MD

James Lewis, II, PharmD, FIDSA
Infectious Disease Clinical Pharmacy Supervisor
Co-Director of Antibiotic Stewardship
Department of Pharmacy
Oregon Health & Science University
Portland, OR

Activity Specialities / Related Topics

Adverse Drug Reactions / ADR, Antibiotics / Anti-Infectives, Contamination & Infection Control, Diagnosis / Assessment / Patient History, Education / Teaching, Hospital-Acquired Infections, Immunology / Immunosuppression, Infectious Disease, Pulmonary Medicine / COPD

Sponsors / Supporters / Grant Providers

Sponsored by the Academy for Continued Healthcare Learning (ACHL). Supported by an educational grant from Merck & Company.

Keywords / Search Terms

ACHL P. aeruginosa, HAP/VAP, infectious disease, Gram-negative, Karam, Simner, Pogue, Lewis, MAD-ID, MAD, pharmacy, antibiotics, resistance, susceptibility, case presentation, COPD, Merck, ACHL Free CE CME Live CE CME

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