Targeted Therapies in Severe Asthma: When to Use Them (and Why)

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Overview / Abstract:

As the incidence of asthma—and the number of patients with severe, treatment-resistant asthma—continues to rise, the need for new management strategies has never been greater. Fortunately, several new tailored biologic therapies have recently been developed for certain patients with treatment-resistant severe asthma. The discovery that severe asthma comprises multiple phenotypes and discrete endotypes linked to distinct patterns of airway remodeling and inflammatory pathophysiology holds the promise of enabling clinicians to better target therapies suited for a given patient’s disease.

This interactive activity has been developed to help clinicians identify severe asthma phenotypes and endotypes, adopt strategies for matching patient types with the most effective targeted therapies, and better understand the mechanisms underlying the use of biologic therapy for the treatment of patients with severe asthma.


Sep 19, 2020


Nurse Practitioner , Nursing CNE, Physician CME, Physician Assistant CME, Respiratory Therapy CE



Credits / Hours

Rutgers Biomedical and Health Sciences designates this enduring material for a maximum of 0 .75 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


In support of improving patient care, this activity has been planned and implemented by Rutgers Biomedical and Health Sciences and RedMedEd. Rutgers Biomedical and Health Sciences is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the health care team.

Presenters / Authors / Faculty

Michael E. Wechsler, MD, MMSc—Program Chair
Professor of Medicine
Director, Cohen Family Asthma Institute
National Jewish Health
Denver, Colorado

Reynold A. Panettieri, Jr., MD
Professor of Medicine
Rutgers Robert Wood Johnson Medical School
Vice Chancellor for Translational Medicine and Science
Rutgers University
New Brunswick, New Jersey

Activity Specialities / Related Topics

Internal Medicine, Family Medicine, Asthma, Allergies / Allergic Reactions

Sponsors / Supporters / Grant Providers

Support for this activity has been provided through an educational grant from Sanofi Genzyme and Regeneron Pharmaceuticals.

Keywords / Search Terms

RedMedEd Asthma, Allergic, Eosinophilic, Neutrophilic. GINA, Mechanism, Phenotype, Endotype, Biomarker, Type 2, Biologic, Anti-IgE, IgE, anti-IgE, Anti–IL-5, IL-5, Anti–IL-4, IL-4, RedMedEd, CME, Free Free CE CME

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