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University of Cincinnati and RedMedEd

Managing Severe Asthma in the Era of Biologics: Early-Onset Asthma

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Overview / Abstract:

In recent years, better understanding of asthma pathophysiology has led to the development of targeted biologics that have improved outcomes for some patients with severe asthma, and the Global Initiative for Asthma (GINA) guidelines now include biologics as a part of its stepwise treatment guidelines for personalized therapy. However, physicians continue to face challenges in determining when to start biologic therapy and which therapy to choose to most effectively manage their patients’ severe asthma symptoms.

In this activity, learners will meet Theresa, a 30-year-old woman who was diagnosed with asthma in infancy and whose asthma has been getting worse over the last several months.

This activity provides guidance in the following areas:

- Determining whether it is appropriate to initiate biologic treatment
- Navigating challenges when prescribing biologic therapies
- Tailoring treatment using the most appropriate targeted biologic agent - based on patient phenotype and endotype.

Following the case presentation, learners will test their ability to apply what they have learned about managing severe asthma in Cranium Challenge.

Expiration

Apr 17, 2021

Discipline(s)

Nurse Practitioner , Nursing CNE, Physician CME, Physician Assistant CME, Respiratory Therapy CE

Format

Online

Credits / Hours

0.5

Accreditation

ACCME, ABIM

Presenters / Authors / Faculty

Reynold A. Panettieri, Jr., MD—Program Chair
Vice Chancellor, Translational Medicine and Science
Director, Rutgers Institute for Translational Medicine and Science
Professor of Medicine, Rutgers University
New Brunswick, New Jersey
Emeritus Professor of Medicine, University of Pennsylvania

Flavia C. Hoyte, MD
Associate Professor of Medicine
Allergy/Immunology Fellowship Training Program
Division of Allergy/Immunology
National Jewish Health
University of Colorado
Denver, Colorado

Michael E. Wechsler, MD, MMSc
Professor of Medicine
Director, Cohen Family Asthma Institute
National Jewish Health
Denver, Colorado

Activity Specialities / Related Topics

Pulmonary Medicine / COPD, Pediatrics, Internal Medicine, Immunology / Immunosuppression, Family Medicine, Asthma, Allergies / Allergic Reactions

Sponsors / Supporters / Grant Providers

This educational activity is supported by an educational grant from GlaxoSmithKline.

Keywords / Search Terms

Web-based, Technology, Online, Virtual, Interactive, CME, Free, Free CE, Free CME, RedMedEd, Patient case, Asthma, Allergic, Eosinophilic, Eosinophils, Early Onset, GINA, Phenotype, Endotype, Biomarker, Type 2, Biologic, Anti-IgE, Anti–IL-5, Anti–IL-4, IgE, IL-5, IL-4, Personalized, Diagnosis, Treatment options, Immunotherapy, Targeted therapy

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