Strategies for PD-L1 Testing and Targeted Therapy With Immune Checkpoint Inhibitors for NSCLC

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Overview / Abstract:

Target Audience
Oncology physicians, nurse practitioners, physician assistants; pulmonary physicians, nurse practitioners, physician assistants; pathologists and pharmacists.

Program Overview
Despite advances in the treatment of non-small cell lung cancer (NSCLC), overall 5-year survival has not significantly improved in recent years. Newly approved and emerging immune checkpoint inhibitor (ICI) therapies offer improvements in survival over chemotherapy alone, but toxicities and immune-related adverse events (irAEs) must be anticipated and managed for successful treatment. In this educational activity, faculty members review the role of PD-L1 testing to determine the best approach to ICI therapy, current efficacy and safety data for ICI therapies in NSCLC, and how to identify and mitigate irAEs. They evaluate clinical trial data, along with patient- and disease-related factors, that allow for the individualization of therapy selection to promote optimal patient outcomes.

After completing this self assessment, you will receive an email directing you to one or more reinforcement activities which will review key teaching points, based on unique educational gaps uncovered in the program.

Learning Objectives
Upon completion of this activity, participants should be better able to:

INTEGRATE optimal testing strategies for PD-L1 in NSCLC with patient-specific characteristics to offer the most appropriate and effective treatment regimens
EVALUATE recent evidence for current and investigational ICIs used in monotherapy and combination regimens for NSCLC
IMPLEMENT evidence-based and guideline-directed strategies to accurately identify and mitigate irAEs associated with ICI therapy


Aug 17, 2022


Physician CME



Credits / Hours




Presenters / Authors / Faculty

Hossein Borghaei, DO, MS
Kurt A. Schalper, MD, PhD

Sponsors / Supporters / Grant Providers

Genmab US, Inc., Regeneron Pharmaceuticals, Inc. and Sanofi Genzyme

Keywords / Search Terms

Relias LLC Relias, Free CME, NSCLC Free CE CME

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