Understanding the Unique Role of HER3 in Oncogenesis

Program Overview

This activity will explore the clinical evidence surrounding the role of HER3 in various tumor types.

Learning Objectives

Upon completion of this activity, participants should be better able to:

Recognize the role of the HER family, and particularly HER3, in oncogenesis
Identify the common causes of disease progression in patients with advanced NSCLC, metastatic breast, colorectal, and other cancers, focusing specifically on treatment failure to epidermal growth factor receptor or anti-estrogen-based therapies
Explain the mechanism of disease of HER3 and HER3-directed antibody drug conjugates (ADCs) under investigation for the treatment of EGFR TKI-resistant NSCLC, breast, and colorectal cancer