BASIC PRINCIPLES OF STERILE COMPOUNDING

CLASS OVERVIEW
For pharmacists and pharmacy technicians engaged in preparing
compounded sterile preparations (CSP). This course puts forward up-to date knowledge, key skills and hands-on training on aseptic techniques,
all in a one day workshop. The contents focus on the standards and
best practices before a CSP reaches a patient. The material is thorough
and balanced to ensure an easy-flow of information. At the end of the
course, you are expected to be well-versed and equipped with skills to
further your career or reinforce your knowledge base.

LEARNING OBJECTIVES
1. Describe the history behind the development of sterile compounding
standards and regulations in the United States
2. Explain the role of the compounder in assuring the safety of compounded sterile preparations.
3. Describe sterile compounding facility requirements and engineering
controls
4. Apply USP risk categories to assigning a proper beyond-use date for
compounded sterile preparations.
5. Define garbing sequence for non-hazardous and hazardous compounding.
6. Explain how environmental conditions are measured and maintained
7. Illustrate how to properly perform moving products, mixing, hand hygiene, fingertips sampling and growth media.
8. Compare and contrast the vascular access options available for
administering parenteral nutrition.
9. Design a parenteral nutrition formulation based on estimated
requirements

CONTENT COVERED:
• Introduction into sterile compounding
• Common pharmaceutical calculations
• Compounding facilities and engineering controls
• Compounding material
• Beyond Use Date (BUD)
• Environmental monitoring
• Quality Assurance QA, and Quality Control QC
• Infection control
• Hand hygiene and garbing
• Proper clean room behavior and material movement
• Aseptic manipulations (Media fill & Fingertips sampling)
• Principles of HEPA-filtered unidirectional airflow
• Measuring and mixing
• Use, calibration, cleaning, and maintenance of all related compounding
equipment
• Handling Hazardous Drugs
• Documentation of compounding process
• Comparison of common intravenous catheters
• Enteral (EN) vs. Parenteral (PN) feeding
• Types of enteral products
• Nutritional requirements in adults
• Considerations for product selection
• Parenteral nutrition 2-in-1 vs. 3-in-1
• Medication co-administration with EN/PN
• Lab work and formula adjustments
• Common feeding errors
• Current vs. proposed USP 79