Long-Chain Fatty Acid Oxidation Disorders: Advances in Nutritional Management

Target Audience
This activity is designed to meet the educational needs of Registered Dietitians.

Program Overview
Long-chain fatty acid oxidation disorders (LC-FAODs) are characterized by acute crises of energy production and chronic energy deficiency during times of physiologic stress and fasting. Clinical complications include recurrent episodes of rhabdomyolysis, weakness, hepatic dysfunction, severe hypoglycemia, hyperammonemia, and cardiomyopathy. Despite a traditional diet therapy, serious complications have persisted. This activity will discuss alternative food sources and other advances in FAOD nutritional management that have the potential to significantly improve outcomes in both pediatric and adult patients.

Learning Objectives
Upon completion of this activity, participants should be better able to:

Provide an overview of LC-FAOD to better understand the pathophysiology of these metabolic disorders
Recognize common clinical symptoms associated with the most common types of LC-FAOD while recognizing the potential for variation in presentation and prognosis
Review general recommendations for the dietary and nutritional management of LC-FAOD patients through sample case scenarios
Explore novel therapies including safety and efficacy, as well as adverse effects and their impact in improving patient outcomes