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How I Treat Paroxysmal Nocturnal Hemoglobinuria (PNH)

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Overview / Abstract:

In this point-counterpoint digital activity, two expert faculty discuss and debate treatment selection for patients with PNH through case-based scenarios. Faculty review mechanisms of action, clinical trial data, and real-world evidence supporting divergent treatment strategies for the presented cases. How do the experts make their initial treatment selections? Why might they choose a C5 inhibitor or a C3 inhibitor? How do they assess response to treatment, and what do they do when treatment response is suboptimal? View the activity and find out!


Jun 30, 2024


Online, Webinar / Webcast / Video

Credits / Hours




Presenters / Authors / Faculty

Jamile M. Shammo, MD, FASCP, FACP
Dr. Marjorie C. Barnett- Dr. Hau C. Kwaan Professor
Division of Hematology/Oncology
Northwestern University Feinberg School of Medicine
Chicago, IL

Carlos de Castro, MD
Professor of Medicine
Duke University School of Medicine
Duke Cancer Institute
Durham, NC

Sponsors / Supporters / Grant Providers

This educational activity is presented in collaboration with Rush University Medical Center and Academy for Continued Healthcare Learning (ACHL).

Supported by educational grants from Alexion Pharmaceuticals and Apellis Pharmaceuticals, Inc

Keywords / Search Terms

ACHL CME, Paroxysmal nocturnal hemoglobinuria, PNH, C5 inhibitor, eculizumab, ravulizumab, C3 inhibitor, pegcetacoplan, hemolysis, thrombosis, complement inhibitors, anemia, transfusion, breakthrough hemolysis, QoL, quality of life Free CE CME

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