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Leveraging BCMA-Directed Therapies for Improved Patient Outcomes in Relapsed/Refractory Multiple Myeloma

STATEMENT OF NEED Multiple myeloma is a disease that remains incurable for most patients, many of whom become refractory to the majority of available treatments (Kumar et al, 2022). It is estimated that 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Agents targeting B-cell maturation antigen (BCMA), including antibody-drug conjugates (ADCs), chimeric antigen receptor (CAR) T-cell therapies, and bis...
i3 Health

Virtual Tumor Board: Multidisciplinary Management of Advanced Soft Tissue Sarcoma

STATEMENT OF NEED Sarcomas, which represent 1% to 2% of adult cancers, are a rare, heterogeneous group of neoplasms originating in the connective tissue. Soft tissue sarcomas, which begin in the muscle, tendons, fat, lymph, blood vessels, and nerves, encompass more than 80 histological subtypes. Approximately 25% of patients develop metastatic disease after curative-intent surgery, and for these patients, treatment options are limited and prognosis is very poor. In recent decades, the ident...
i3 Health

Exploring New Treatment Advances for Acid Sphingomyelinase Deficiency in Adults

STATEMENT OF NEED Acid sphingomyelinase deficiency (ASMD) is a rare, hereditary lysosomal storage disease with multisystemic manifestations, including splenomegaly, hepatomegaly, interstitial lung disease, dyslipidemia, bone marrow and lymph node involvement, and sometimes neurological and peripheral nerve involvement. While the most severe form of ASMD, infantile neurovisceral ASMD, results in death in early childhood, chronic forms of ASMD have more prolonged survival but are associated w...
i3 Health

Is It Safe? Safety Surveillance through the Antiretroviral Pregnancy Registry

Is It Safe? Safety Surveillance through the Antiretroviral Pregnancy Registry Release Date: June 2, 2023 Expiration Date: June 2, 2024 Estimated Time to Complete: 1.25 hour VIEW ACTIVITY Clinical Gap and Educational Need Antiretroviral therapy should be initiated for all persons with HIV who are pregnant regardless of CD4 count according to current guidelines. There is often minimal data available to make recommendations, however, for use in pregnancy. One key consideration is...
American Academy of CME

Gastroenterology 2024 - LIVE STREAMING

The Comprehensive 2024 Gastroenterology Update This highly rated Harvard Medical School CME program ensures participants are current with state-of-the-art GI strategies and clinical practices. It covers recent advances and their impact on clinical approaches and on patient outcomes. Updates, best practices, and new guidelines are presented by nationally recognized GI experts and master clinicians. Practical, Results-Driven Education Highlights of the 2024 program include: • Updated...
Harvard Medical School

FOP: Enhancing Diagnosis and Management to Improve Patients’ Quality of Life

Target Audience The educational design of this activity addresses the needs of the primary audience of orthopedists, bone specialists, rheumatologists, pediatric rheumatologists, and genetic counselors, and the secondary audience of PCPs, pediatricians, dermatologists, endocrinologists, occupational therapists, oncologists, general practice NPs and PAs, and specialist NPs and PAs. Program Overview Because fibrodysplasia ossificans progressiva, or FOP, is exceedingly rare, even specialists...
Partners for Advancing Clinical Education (PACE) and PlatformQ Health Education, LLC (PQHE), in collaboration with the National Organization for Rare Disorders, Inc. (NORD) and the International Fibrodysplasia Ossificans Progressiva Association (IFOPA) an

Dialogues about FOP: What Patients Wish More Doctors Knew to Enhance Early Recognition and Management

Target Audience The educational design of this activity addresses the needs of the primary audience of PCPs, pediatricians, dermatologists, endocrinologists, occupational therapists, oncologists, general practice NPs and PAs, specialist NPs and PAs, and the secondary audience of orthopedists, bone specialists, rheumatologists, pediatric rheumatologists, genetic counselors, and dentists. Statement of Need/Program Overview Fibrodysplasia ossificans progressiva (FOP) causes abnormal bone for...
Relias LLC

Intensive Review of Nephrology - LIVE STREAMING

With over 70 interactive lectures, case discussions, board preparation sessions, and supplementary lectures, this CME program provides a comprehensive review of state-of-the-art nephrology practices offered by the clinical faculty of Harvard Medical School. It offers accelerated learning for: - Clinicians seeking a practical and comprehensive review that ensures they are up to date across all major areas of nephrology: • The latest options for diagnosis: what to choose, when, and wh...
Harvard Medical School

Therapeutic Advancements for the Treatment of High-Risk MDS: Future Opportunities to Improve Patient Survival and Quality of Life

Stay up to date on the evolving risk classification for myelodysplastic syndromes (MDS) and current treatment guidelines for patients with high-risk disease in this self-directed education with leading oncology experts. Expert commentary from Courtney DiNardo, MD from MD Anderson Cancer Center and Dr. Dan Pollyea from the University of Colorado School of Medicine provides insights on emerging therapies that could soon improve management of high-risk MDS. Be ready to incorporate these emerging ...
ACHL

Raising the Bar in ATTR Amyloidosis A Training Set on Diagnosis and Treatment

There is considerable heterogeneity in the clinical manifestations of ATTR amyloidosis, which are often dependent on both genetic and environmental factors. Once a fatal diagnosis with no effective therapies available, research in ATTR amyloidosis is rapidly evolving and new pharmacotherapies that demonstrate improved quality of life and life expectancy for patients have been developed. Despite this progress, treatment options remain limited, underscoring the need to continue to expand the tre...
Integritas Communications

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