A Case-Based Roadmap for Improved Patient Outcomes in Psoriatic Arthritis
Patients with psoriatic arthritis (PsA) experience significant disease burden due to incomplete diagnostic evaluation and suboptimal use of effective therapies. In this case-based activity, Dr. Leonard Calabrese of the Cleveland Clinic addressing these practice gaps by sharing his recommendations for patient management at critical decision points in the diagnosis and treatment of patients with P...
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A New Frontier in the Co-Management of Thyroid Eye Disease
Thyroid eye disease, also known as Graves’ orbitopathy, is a potentially serious, progressive autoimmune disease that most often occurs in people with hyperthyroidism, ie, Graves’ disease. Kimberley Cockerham, MD, FACS, moderates this series of six, paired conversations between endocrinologist Terry J. Smith, MD, and eye specialists Wendy W. Lee, MD, and Raymond Douglas, MD, PhD, to explore ...
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Addressing Challenges in Diagnosis and Treatment of Low-Grade Upper Tract Urothelial Carcinoma
OVERVIEW
Upper tract urothelial carcinoma (UTUC) has many similarities to bladder carcinoma, but also some important differences. Join Dr. Seth Lerner, as he contrasts these 2 diseases, as well as important differences between low-grade and high-grade UTUC. Dr. Lerner highlights important considerations in the instruments, imaging, and biopsy techniques for diagnosing low-grade UTUC. Surgical o...
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Addressing Challenges in Treatment of Growth Hormone Deficiency
Growth hormone deficiency (GHD) is a complex disorder that can present in childhood or adulthood and results in growth failure along with more serious complications, including delayed bone age, increased adiposity, and systemic symptoms. This activity reviews the complex management of GHD, from diagnosis through treatment. The activity also reviews the wide array of established and novel recombi...
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Advanced Basal Cell Carcinoma: How to Navigate Challenging Clinical Scenarios With Systemic Treatment
Join Karl Lewis, MD, and Aleksandar Sekulic, MD, PhD, as they discuss the importance of the hedgehog pathway in the pathogenesis of BCC and the role of hedgehog inhibitors in advanced BCC. Evidence related to the safety and efficacy of the approved hedgehog inhibitors sonidegib and vismodegib are discussed, with recommendations for optimizing their use. Case studies are utilized to share the fac...
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Advanced Ovarian Cancer and PARP Inhibitors: Clinical Insights and Impact on New Data
In this CME activity, Susana M. Campos, MD, MS, MPH, reviews some of the recent clinical developments in the treatment of patients with advanced ovarian cancer with PARP inhibitors. We welcome you to learn more about the updated data from key clinical studies of PARP inhibitor maintenance therapy in advanced ovarian cancer, and the implications of the results on the current and emerging concepts...
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An Interactive Guide to the Underdiagnosed, Underestimated, but Treatable Metabolic Disorders
This infographic activity uses a self-directed, visual update to the state-of-the-art diagnosis and management of treatable lysosomal storage disorders. Much of what you learned in your primary training may be outdated because of rapid advances in genetic, molecular, and clinical approaches to these conditions. While the LSDs were often fatal conditions, new treatments have completely changed th...
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Biologics in Severe Asthma: Optimizing Therapeutic Selection and Patient Outcomes
This case-based activity focuses on considerations, including phenotypes and biomarkers, in individualizing treatment with the 5 monoclonal antibodies currently approved for severe asthma in the United States. The role of shared decision-making is discussed as an approach to individualizing therapy and improving patient outcomes. Clinical criteria for assessing treatment response to biologic the...
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Diagnosis, Treatment and Prevention Therapies in Primary Headache Disorders
ACTIVITY OVERVIEW
Primary headache disorders are a major cause of disability and a common reason people seek medical care. However, distinguishing a primary from a secondary headache disorder, as well as among primary headache disorders, is often challenging. Focusing on cluster and migraine, Drs. Jessica Ailani and Stewart Tepper provide criteria and strategies to overcome this challenge in th...
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Exploring Best Practices for Diagnosis and Management of Adult-Onset Stills Disease
Adult-onset Still’s disease (AOSD) is a rare, polygenic autoinflammatory syndrome with a pathogenesis similar to systemic juvenile inflammatory arthritis. Join Drs. Petros Efthimiou and Olga Petryna as they discuss making the diagnosis of AOSD through interpretation of clinical and laboratory findings and careful exclusion of other diseases. The faculty review the evidence related to the varie...
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Exploring Best Practices for Diagnosis and Management of Hypereosinophilic Syndrome
Hypereosinophilic syndromes (HESs) are a broad group of disorders that can lead to serious complications, including cardiovascular disease, cerebrovascular disease, and death. Due to their rarity, however, HESs are challenging to diagnose and treat. In this in-depth review, presented by Princess Ogbogu, MD, and developed in collaboration with Michael Wechsler, MD, MMSc, the wide-ranging presenta...
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From Clinical Trials to Clinical Implications: PARP Inhibitor Combinations in Advanced Prostate Cancer
Metastatic castration-resistant prostate cancer (mCRPC) is a heterogeneous disease with high disease burden and poor outcomes despite androgen deprivation therapy. This activity by Neeraj Agarwal, MD, provides strategies for germline genetic testing and somatic testing to best inform treatment. Poly (ADP-ribose) polymerase (PARP) inhibitor therapy provides a unique approach to treatment. Dr. Aga...
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Meeting the Challenges in Management of Sickle Cell Disease
No longer a life-threatening disease, sickle cell disease (SCD) has become a chronic disease with life-threatening events that requires coordinated care by a multidisciplinary care team. Join Michael R. DeBaun, MD, MPH, and Collin Montgomery, APRN, as they discuss the acute and chronic complications experienced by individuals with SCD and the barriers they often encounter. The faculty offer real...
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Nontuberculous Mycobacterial Lung Disease: Real-World Application of New Guidelines and Treatment Advances
Nontuberculosis mycobacterial lung disease (NTM-LD) is a frequently fatal lung disease that is now more common than tuberculosis in the United States. Treatment is generally very challenging due to lack of medications approved for first-line therapy, adverse events, drug-drug interactions, need for long-term dual and triple combination therapy, among other issues. In the first of this 2-part act...
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Optimal Prehospital Management of Seizure Emergencies
In this program, the faculty will review and provide updates on the guidelines for managing seizure emergencies and address how participants can reduce the barriers to prehospital treatment through the use of Seizure Action Plans. They also will discuss recent clinical trials that may improve caregiver acceptance of rescue medications for status epilepticus. In addition, the faculty will address...
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Resear4ch Developments in Psoriasis
Plaque psoriasis is responsible for a substantial burden on patients, their families, and the healthcare system. To address this burden, important treatment advances continue to be made, including a better understanding of the long-term safety and efficacy of approved medications, as well as the introduction of new classes of medications. Join Steven Feldman, MD, PhD, and Abby Van Voorhees, MD, ...
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Research Updates in Gout: Improving Response Rate to Therapy
Dr. Brian Mandell and Dr. Naomi Schlesinger discuss recent published evidence related to gout, as well as study results presented at the American College of Rheumatology Convergence 2020 virtual annual meeting. Dr. Schlesinger begins with an introduction on a recent published systematic review indicating that the manifestations of gout extend beyond the joints, affecting other organs and tissues...
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TEAM UP: Defining and Refining Optimal HIV Care During the COVID-19 Pandemic
In this webcast series, members of the DAP Health team review key data and discuss their real-world experiences providing care for persons living with HIV during the COVID-19 pandemic. DAP Health opened one of California’s first COVID-19 clinics and hotlines to offer screening, testing, and treatment.
Topics covered in this webcast series include:
COVID-19–Related Complications in Pers...
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