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Best Practices in Nursing Management of Chemotherapy-Induced Peripheral Neuropathy
STATEMENT OF NEED
Chemotherapy-induced peripheral neuropathy (CIPN) is a complication of cancer treatment that may impair quality of life and lead to treatment dose reductions or discontinuation in severe cases. In one study of 123 patients receiving taxane therapy for breast cancer, 17% required dose reductions because of CIPN (Bhatnagar et al, 2014). Whereas in some patients the symptoms of...
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Current Challenges and New Opportunities in Follicular Lymphoma
STATEMENT OF NEED
Of the estimated 74,680 new cases of non-Hodgkin lymphoma each year in the United States, approximately 35% are follicular lymphoma (FL), an indolent, difficult-to-treat B-cell malignancy. Most patients are diagnosed at an average age of 65 years. Despite the introduction of novel therapies during the past decade, complications such as delayed presentation and treatment and ...
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Current Trends and Future Directions in Targeted Therapies for Advanced Renal Cell Carcinoma
STATEMENT OF NEED
Based on recent estimates, kidney cancer accounts for approximately 4% of all cancer diagnoses in the United States. An estimated 65,300 new cases are reported each year and more than 14,000 people die of the disease. Renal cell carcinoma (RCC), which comprises nearly 90% of all kidney cancers, is characterized by a lack of early warning signs, diverse clinical manifestation...
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Management of Cancer Pain: Current Guidelines
STATEMENT OF NEED
Cancer patients often experience a range of symptoms that negatively impact their quality of life. Among the most debilitating is pain. Despite efforts to increase awareness, cancer pain is still underdiagnosed and undertreated and patients do not obtain complete relief. Although numerous management guidelines for cancer pain have been developed, most health care practitione...
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Management of Venous Thromboembolism in Ambulatory Patients With Cancer
STATEMENT OF NEED
Venous thromboembolism (VTE) is a common and potentially life-threatening complication in patients with cancer. There are two main types of VTE: deep vein thrombosis (DVT) and pulmonary embolus (PE), which can cause right heart failure, cardiopulmonary collapse, and death (Ozaki & Bartholomew, 2012). Patients who develop PE require hospitalization, increased oxygen requireme...
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Management of Venous Thromboembolism in Hospitalized Patients With Cancer
STATEMENT OF NEED
Venous thromboembolism (VTE), which consists primarily of deep vein thrombosis (DVT) and pulmonary embolism (PE), is a life-threatening complication in hospitalized patients with cancer, and is associated with a 2- to 6-fold increase in likelihood of death (NCCN, 2016). The mainstay of treatment is anticoagulation; however, since cancer patients with VTE have higher rates of...
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Nursing Management of Bone Health in Patients With Cancer
STATEMENT OF NEED
Many tumors, such as prostate, breast, lung, and multiple myeloma, affect bone health. Once cancer spreads to the skeletal system, the risk for pain, fractures, hypercalcemia, and nerve compression increases considerably. Several studies have shown that the use of antiresorptive agents such as bisphosphonates and monoclonal antibodies can reduce the morbidity of skeletal com...
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Nursing Management of Cancer Treatment-Induced Cardiotoxicity
STATEMENT OF NEED
Several studies reveal that certain cancer therapies adversely affect the heart and lead to various types of injuries, which often result in death. Adverse cardiac effects may occur immediately after cessation of therapy or, in some cases, years after the therapy has been discontinued. Often the cardiotoxicity presents in subtle ways, and a lack of awareness results in high ...
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Nursing Strategies to Optimize Treatment Experiences in Hormone-Receptor Positive, HER2-Negative Metastatic Breast Cancer
STATEMENT OF NEED
Breast cancer accounts for nearly 30% of cancer diagnoses among women in the United States, and is the second-leading cause of cancer death in this population. Although many women benefit from regular screening as well as earlier and improved treatment, approximately 10% present with metastatic disease, and 30% with no initial lymph node involvement eventually develop metast...
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Optimizing Management of Carcinoid Syndrome in Patients With Neuroendocrine Tumors
STATEMENT OF NEED
Carcinoid syndrome refers to a constellation of symptoms caused by the systemic release of humoral factors such as polypeptides, biogenic amines, and prostaglandins, mostly from well-differentiated neuroendocrine tumors. Patients frequently experience flushing, abdominal cramps, bronchospasms, hypotension, and diarrhea, which lead to impaired quality of life and daily functi...
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Optimizing the Management of Advanced Cervical Cancer With Checkpoint Inhibitor Therapy
STATEMENT OF NEED
There are an estimated 13,240 new cases of cervical cancer in the United States each year, and 4,170 people die of the disease. Due to screening and heightened awareness, deaths have declined during the past few decades. However, the malignancy continues to be a global health concern and is considered an epidemic in parts of the world. A significant proportion of patients de...
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Prevention of Medical Errors in Nursing Practice
STATEMENT OF NEED
Medical errors are among the most common health-threatening mistakes that affect patient care, accounting for as many as 250,000 deaths per year in the United States (Makary & Daniel, 2016). Medical errors are considered a global problem, complicating a patient’s primary condition for which they needed medical attention. These errors can lead to adverse outcomes such as incr...
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