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An Evolving Treatment Landscape for Inflammatory Disease: Debating Interchangeability, Efficacy, and Safety of Biosimilars
Health care spending has grown much faster than the rest of the economy, and this trend is seemingly unsustainable.1 Biologic agents are highly effective against inflammatory diseases, but may be restricted by many health care plans due to cost. Biosimilars offer a potential solution as a cost-effective alternative to biologic agents. Biosimilars have been available in Europe since 2005. In the ...
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Bringing Health Care Providers Together to Diagnose and Treat Idiopathic Pulmonary Fibrosis: A Patient Simulation
Although the most common of the restrictive lung diseases, idiopathic pulmonary fibrosis (IPF) is a rare but deadly disease, affecting an estimated 6.8 to 42.7 per 100,000 people, with higher rates in those older than 65 years, and resulting in approximately 40,000 deaths annually in the United States.
Education to community pulmonologists, radiologists, and primary care physicians, as well a...
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Challenges in Patient Safety in Psychiatry
Patients with mental illness are at higher risk for adverse events including suicide, lack of medication adherence, and less likely to seek help during relapse. As pressure to discharge increases in addition to treatment plans, patients with mental illness must also have a safety plan beyond the length of hospitalization that makes the patient an equal participant and involves their entire care ...
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Deep Remission, Mucosal Healing, and Top-Down Treatment Strategies in Ulcerative Colitis: An Infographic Journey
Ulcerative colitis (UC) is an inflammatory bowel disease with a progressive course characterized by exacerbations and remissions. Traditionally, the goals of therapy for UC have entailed resolution of clinical symptoms such as rectal bleeding, bloody diarrhea, abdominal cramps, pain, and fatigue. However, treatment goals for UC have evolved to a treat-to-target strategy with targets such as muco...
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Deep Remission, Top-Down Treatment Strategies and Real-World Data in Patients with UC: An Interactive and Innovative Case Series
Ulcerative colitis (UC) is an inflammatory bowel disease with a progressive course characterized by exacerbations and remissions. Traditionally, the goals of therapy for UC have entailed resolution of clinical symptoms such as rectal bleeding, bloody diarrhea, abdominal cramps, pain, and fatigue. However, treatment goals for UC have evolved to a treat-to-target strategy with targets such as muco...
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From Symptom Recognition to Narcolepsy Diagnosis: Shortening the Diagnostic Journey: A Moderated Discussion with the Experts and Q&A
Patients with narcolepsy often face a long journey on their path to diagnosis and effective treatment. Combating the negative impact of narcolepsy on the lives of those affected requires that both the general public and the medical community increase their awareness of the symptoms of narcolepsy, in particular, the most common presenting symptoms: cataplexy and excessive daytime sleepiness.
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Integrated Care Strategies to Address the Impact of Residual Symptoms on Functional Outcomes in MDD
Depression is one of the leading causes of disability worldwide. It affects individuals, families, businesses, and society and is common in patients seeking care in the primary care setting. Approximately 55% of patients will respond to treatment with the initial antidepressant. Yet, even in those patients who respond to treatment and achieve remission, residual symptoms can significantly inhibi...
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Problem Based Learning in HBV: A Patient Simulation for Improving Treatment Decisions and Long-Term Care
Hepatitis B virus (HBV) infection is a largely undetected and untreated disease in the United States despite the availability of screening guidelines and prophylactic vaccines. Chronic HBV infection causes severe complications, including cirrhosis and hepatocellular carcinoma in 20% - 30% of patients. As a result, HBV infection is the most common reason for liver transplantation.
While recomm...
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Recognizing the Symptoms of Narcolepsy: Screening Your Sleepy Patient for Cataplexy: A Moderated Discussion with the Experts and Q&A
Patients with narcolepsy often face a long journey on their path to diagnosis and effective treatment. Combating the negative impact of narcolepsy on the lives of those affected requires that both the general public and the medical community increase their awareness of the symptoms of narcolepsy, in particular, the most common presenting symptoms: cataplexy and excessive daytime sleepiness.
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Taking Action Against Chronic Hepatitis B Virus Infection: Counseling Patients on Serological Results
Hepatitis B virus (HBV) infection is a largely undetected and untreated disease in the United States. Only 33% of the estimated one million Americans living with HBV are aware that they are infected, placing them at risk for spreading the infection to others, and developing liver failure, cirrhosis, or hepatocellular carcinoma (HCC). As a result, HBV infection is the most common reason for liver...
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Taking Action Against Chronic Hepatitis B Virus Infection: Determining Which Patients to Treat or Monitor
Hepatitis B virus (HBV) infection is a largely undetected and untreated disease in the United States. Only 33% of the estimated one million Americans living with HBV are aware that they are infected, placing them at risk for spreading the infection to others, and developing liver failure, cirrhosis, or hepatocellular carcinoma (HCC). As a result, HBV infection is the most common reason for liver...
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The Immunosuppression Balancing Act: Preserving Long-Term Allograft Function for Optimal Patient Outcomes
The current goal of transplant medicine and immunology is to develop strategies to extend the life and functionality of every allograft. Outcomes of renal and liver transplantation have improved; yet, allograft loss remains a substantial problem associated with increased morbidity, mortality, and costs.
Education to transplant clinicians about evaluating all aspects of post-transplant care, i...
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Treating the Full Spectrum of Narcolepsy: Improving Nighttime Symptoms to Enhance Daytime Quality of Life: A Moderated Discussion with the Experts and Q&A
Patients with narcolepsy often face a long journey on their path to diagnosis and effective treatment. Combating the negative impact of narcolepsy on the lives of those affected requires that both the general public and the medical community increase their awareness of the symptoms of narcolepsy, in particular, the most common presenting symptoms: cataplexy and excessive daytime sleepiness.
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