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Exploring Novel Treatments for Rett Syndrome

STATEMENT OF NEED Rett syndrome is a rare, debilitating neurodevelopmental disorder almost always associated with a spontaneous mutation in the methyl-CpG-binding protein 2 (MECP2) gene on the X-chromosome. Affected individuals experience loss of purposeful hand skills, abnormalities in gait, loss of spoken language, and stereotypic hand movements, with more severe manifestations including seizures, autistic features, autonomic nervous system dysfunction, breathing abnormalities, sleep dist...
i3 Health

Best of Lipid Forum®: Examining the Role of Lp(a) as a Risk Factor in Atherosclerotic Cardiovascular Disease

Lipoprotein(a) [Lp(a)] is a low-density lipoprotein particle that is associated with poor cardiovascular prognosis due to its pro-atherogenic, pro-thrombotic, pro-inflammatory and pro-oxidative properties. Unfortunately, traditional lipid-lowering therapy does not provide sufficient Lp(a) reduction. High levels of Lp(a) are an independent and causal risk factor for atherosclerotic cardiovascular disease (ASCVD) through mechanisms associated with increased atherogenesis, inflammation, and throm...
Vindico Medical Education

Best of Lipid Forum®: Examining the Role of Lp(a) as a Risk Factor in Atherosclerotic Cardiovascular Disease

Lipoprotein(a) [Lp(a)] is a low-density lipoprotein particle that is associated with poor cardiovascular prognosis due to its pro-atherogenic, pro-thrombotic, pro-inflammatory and pro-oxidative properties. Unfortunately, traditional lipid-lowering therapy does not provide sufficient Lp(a) reduction. High levels of Lp(a) are an independent and causal risk factor for atherosclerotic cardiovascular diseases (ASCVD) through mechanisms associated with increased atherogenesis, inflammation, and thro...
Vindico Medical Education

Operation Game- A Patient’s Journey Through HeFH: Diagnosis and Management

Target Audience This activity has been designed to address the educational needs of cardiologists, cardiology nurses, lipid specialists, and primary care clinicians, including internists, pharmacists, nurses, nurse practitioners, PAs, and dietitians. It may also benefit other healthcare providers who manage patients with hypercholesterolemia. Program Overview Nonstatins are an essential therapy for lowering low-density lipoprotein cholesterol (LDL-C) levels in high-risk patients, such as ...
Relias LLC

Parenteral Nutrition Solutions: Developing a Playbook for the Multidisciplinary Team

In these symposium highlights, a multidisciplinary panel of experts discuss a range of topics, including the role of indirect calorimetry, protein requirements, intravenous lipid emulsions, and the nutrition support team. Also highlighted are a real-world patient case and the questions and answers/panel discussion. An accompanying infographic on the importance of the nutrition support team and how to organize one can be downloaded and shared with your team.
ACHL

Treating Hepatitis C in Patients with HIV Disease

This course addresses the complexities of HIV disease in the era of improved survival: management of HIV co-infection. Outcome Objectives: As a result of completing this activity, the participant will be better able to: - Diagnose the clinical syndrome of porphyria cutanea tarda. - Diagnose hepatitis C. - Adjust the treatment of hepatitis C based on viral genotype and liver pathology.
Virtual Lecture Hall (University of Arizona College of Medicine - Tucson)

The Immune Reconstitution Syndrome in AIDS

This course addresses the complexities of HIV disease in the era of improved survival: recognition and management of the immune reconstitution syndrome. Outcome Objectives: As a result of completing this activity, the participant will be better able to: - Recognize that restoration of immunologic function in persons with HIV disease may lead to a worsening clinical picture, the immune reconstitution syndrome. - Diagnose and manage occult opportunistic infections in persons with newly...
Virtual Lecture Hall (University of Arizona College of Medicine - Tucson)

Understanding Cholesterol Guidelines and Implementing Non-statins in High-Risk Populations: Paired Conversations and Case Vignettes

An interprofessional faculty of primary care and specialty clinicians discuss real-world issues in managing patients with complex and challenging dyslipidemia, including elevated lipoprotein a (Lp(a)). Several paired conversations serve as the foundation for discussions related to recent cholesterol guidelines, patient risk stratification, and recommended goals for patients at risk of atherosclerotic cardiovascular disease. Two case vignettes provide the basis for robust discussion among the f...
Annenberg Center for Health Sciences at Eisenhower

Unmasking Multiple Myeloma and Its Precursor Conditions in Primary Care

For multiple myeloma (MM) patients to receive the most appropriate care, a quick and accurate diagnosis is paramount. This is especially the case for Black patients, as diagnosis has historically been slower in Black patients"even though MM is twice as common in Black Americans than in White Americans. Additionally, MM precursor conditions such as monoclonal gammopathy of undetermined significance are seen more frequently in Black Americans than in White Americans. Primary care providers ...
Penn State College of Medicine

Nutrition and Depression: Advanced Clinical Concepts

Depression is an increasingly common, complex, inflammatory condition that co-occurs with a host of other conditions. This course will examine how we can combat depression through nutrition, starting with an exploration of the etiology of depression –taking a look at the role of neurotransmitters, the HPA axis and cortisol, gene expression (epigenetics), upregulation and downregulation, and the connections between depression and immunity and depression and obesity.We will then turn our atte...
Professional Development Resources

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