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Expert Guidance on Current Standards and New Directions in Newly Diagnosed Multiple Myeloma
STATEMENT OF NEED
An estimated 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Characterized by clonal proliferation of malignant plasma cells in the bone marrow, multiple myeloma is associated with anemia, renal insufficiency, bone destruction, and hypercalcemia, all of which significantly impact patients’ quality of life. The development of novel therapies and combinations in recent years, inclu... |
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Pathology and Oncology Expert Perspectives in the Management of Triple-Negative Breast Cancer: Case Explorations and Answers to FAQs
STATEMENT OF NEED
Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for approximately 10% to 15% of breast cancer diagnoses and is characterized by the absence of estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2 (HER2). TNBC is more common in Black women and in women under the age of 40 (ACS, 2023). Compared with other subtypes of invasive breast cancer, TNBC has high rates of metastasis and a poor prognosis. Due to the lack ... |
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Putting the Freeze on Cold Agglutinin Disease
STATEMENT OF NEED
Cold agglutinin disease (CAD) is a rare subtype of autoimmune hemolytic anemia (AIHA) in which antibodies cause hemolysis at cold temperatures, generally between 37º to 39º Fahrenheit. Approximately 1 in a million people are affected by CAD annually, with onset usually occurring between the ages of 40 and 80 years. Individuals commonly experience fatigue, dizziness, palpitations, and shortness of breath caused by the anemia; jaundice caused by degradation of hemoglobin i... |
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Exploring New Treatment Advances for Acid Sphingomyelinase Deficiency in Adults
STATEMENT OF NEED
Acid sphingomyelinase deficiency (ASMD) is a rare, hereditary lysosomal storage disease with multisystemic manifestations, including splenomegaly, hepatomegaly, interstitial lung disease, dyslipidemia, bone marrow and lymph node involvement, and sometimes neurological and peripheral nerve involvement. While the most severe form of ASMD, infantile neurovisceral ASMD, results in death in early childhood, chronic forms of ASMD have more prolonged survival but are associated w... |
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Recurrent and Metastatic HNSCC: New Insights and Real-World Evidence for Improved Patient Outcomes
STATEMENT OF NEED
Head and neck cancers represent a heterogeneous group of tumors that originate in the lip/oral cavity, hypopharynx, oropharynx, nasopharynx, and larynx. An estimated 66,470 new cases are diagnosed in the United States annually, and 15,050 people die of the disease (Siegel et al, 2022). Approximately 90% of cases are classified as head and neck squamous cell carcinoma (HNSCC). Treatment of HNSCC is complicated by numerous factors, including differing therapeutic strategies ... |
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The Importance of Early Recognition of Tay-Sachs and Sandhoff Disease
Faculty experts Jeanine Jarnes, PharmD, and Chester Whitley, MD, PhD, delve into the rare and difficult to diagnose GM2-gangliosidoses Tays-Sachs and Sandhoff diseases. Following a discussion of the etiology and pathophysiology of these diseases, the faculty use real-life cases to illustrate the various phenotypes of these conditions, as well as key presenting signs and symptoms. Diagnostic approaches are discussed, alongside current standards of care, including supportive and palliative treat... |
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It Takes a Village: Working Together to Reduce Racial Inequities in Maternal Morbidity and Mortality
Maternal morbidity and mortality rates are unacceptably high in the United States (US). In fact, Black women are two to three times more likely to die from pregnancy-related causes than white women, prompting the US Department of Health and Human Services to state that maternal deaths are a public health crisis. What can you do to address these inequities in maternal health? Two experts in this field will discuss the latest data on maternal deaths and frame practical and supportive strategies ... |
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Nursing Management of Tumor Lysis Syndrome
STATEMENT OF NEED
Tumor lysis syndrome (TLS) is an oncological emergency that occurs when massive tumor lysis causes the rapid release of intracellular components into the bloodstream. Electrolyte imbalances characterized by hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia may be severe enough to cause acute renal failure, cardiac arrhythmias, seizures, and even death. Current advances in cancer therapies can increase the incidence of TLS; therefore, identification of patien... |
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Thymidine Kinase 2 Deficiency: From Diagnostic Odyssey to Timely Diagnosis and Treatment
Mary Kay Koenig, MD, a leader in the management of patients with mitochondrial diseases, delves into the complexities of managing patients with thymidine kinase 2 deficiency (TK2d). In this 1-hour activity, Dr. Koenig shares her insights in the clinical presentation of TK2d through real case studies and offers guidance on overcoming the ‘diagnostic odyssey’ experienced by many patients with mitochondrial disease. She also discusses the clinical criteria for referring patients to specialize... |
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Treatment Considerations in Cutaneous Melanoma: From Early Stage to Late/Advanced Stage
Jason J. Luke, MD, discusses the impact of evolving therapies on the disease burden, survival, and treatment tolerability for patients with cutaneous melanoma. Recent clinical trial results and guideline updates for both perioperative and metastatic cutaneous melanoma are reviewed. To provide patient-centric care, Dr. Luke shares his expert insights and recommendations for individualizing treatment selection and sequencing, as well as providing supportive care and adverse event management. |
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Exploring Advances in the Early Diagnosis and Treatment of Alzheimer Disease
STATEMENT OF NEED
Alzheimer disease, the most common form of dementia among older adults, is a slowly progressive neurogenerative disease that affects approximately 6 million Americans aged 65 and older (Rajan et al, 2021). Symptoms of Alzheimer disease include memory loss, confusion, impulsive behavior, difficulty with language, mood and personality changes, hallucinations, and increased anxiety or aggression, with severe symptoms such as physical decline, difficulty swallowing, and inabil... |
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“THEY TOO SHALL PASS: A JOURNEY THROUGH CARING FOR ADULT TRANSGENDER PATIENTS”
CLASS OVERVIEW
This CE will allow providers to gain a solid foundation regarding transgender healthcare and the skills necessary to provide healthcare for transgender patients in a safe, supportive and welcoming environment
EDUCATIONAL/LEARNING OBJECTIVES:
1. Recognize and apply gender confirming and gender-nonconforming terminology to current practice
2. Review epidemiology of the LGBTQIA+ population
3. Design a welcoming, safe, and supportive environment for patients within the LGBTQI... |
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Gender and Transgender Identity
Gender and Transgender Identity is a 3-hour online continuing education (CE) course that reviews issues in the formation of gender and transgender identity. After viewing oneself as a human being, the most important aspect of our self-concept is that we are a male person or a female person. That is the very essence of our humanness and the most basic sense of who we are. To experience a conflict between our physical body and our concept of maleness or femaleness is the most fundamental existen... |
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Nurturing the Child with Special Needs
Nurturing the Child with Special Needs is a 4-hour online continuing education (CE/CEU) course that provides strategies for healthcare professionals and parents to support children with special needs to manage behavior, sensory issues, and language challenges.
All children need to feel a sense of belonging and significant in ways that elicit positive responses from those around them. Sometimes, a child with special needs can alienate others when attempting to have their unique requirements ... |
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