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i3 Health

Improving Treatment Outcomes of Patients With Waldenstrom Macroglobulinemia

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Overview / Abstract:


Waldenstrom macroglobulinemia (WM) is a rare lymphoproliferative disorder characterized by lymphoplasmacytic bone marrow infiltration and the presence of serum monoclonal IgM. With an estimated 1,500 new cases reported in the United States annually, the malignancy accounts for 2% of non-Hodgkin lymphomas. Unfortunately, WM is considered incurable with available therapies. Patients with low- and intermediate-risk disease have 5-year survival rates of 87% and 68%, respectively, whereas those with high-risk disease have a 5-year survival rate of only 36%.


Hematology/oncology physicians, oncology advanced practitioners, oncology nurses, and other health care professionals involved in the treatment of patients with WM


Upon completion of this activity, participants should be able to:

1. Assess factors to risk stratify patients with WM
2. Differentiate emerging efficacy and safety data on novel therapeutic approaches for treatment-naive and relapsed/refractory WM
3. Apply strategies to monitor and manage adverse events associated with novel therapies for WM

Note: The learning objectives listed above apply to nurse practitioners and registered nurses in addition to physicians.


May 09, 2020


Nurse Practitioner , Nursing CNE, Physician CME, Physician Assistant CME


Monograph, Online

Credits / Hours




Presenters / Authors / Faculty

Morie A. Gertz, MD, MACP (Chairperson)
Professor of Medicine
Rochester Mayo Clinic

Toni Dubeau, RN, NP
Nurse Practitioner
Bing Center for Waldenström's Macroglobulinemia

Sponsors / Supporters / Grant Providers

This activity is supported by an independent educational grant from Pharmacyclics.

Keywords / Search Terms

i3 Health i3 Health, WM, Waldenstrom macroglobulinemia, Waldenstrom, hematologic malignancies, hematology, oncology, CME, CE, free CME, free CE, oncology CME, oncology CME Free CE CME

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