Activity Provided By:

Integritas Communications

Making the Call in Nonadvanced Systemic Mastocytosis Optimizing Multidisciplinary Management

Overview / Abstract:	Series Overview Nonadvanced systemic mastocytosis (SM) is a group of rare disorders characterized by mast cell accumulation that results in a significant and varied symptomatic burden to the patient. The most prevalent of these symptoms include gastrointestinal symptoms, dermatological symptoms, and recurrent anaphylaxis in response to a variety of triggers such as food, insect venom, and medications. In this Phone-a-Friend series, a multidisciplinary panel of faculty experts will address the importance of high-sensitivity assays to detect the KIT D816V mutation that is responsible for most cases of nonadvanced SM, the recently updated World Health Organization diagnostic criteria, the various triggers of mast cell activation, symptom assessment techniques, and patient education. The faculty will also discuss individualization of symptom-directed treatment strategies, evolving treatment options, and newly approved targeted therapies for the treatment of nonadvanced SM. Target Audience The educational design of this series addresses the needs of allergy/clinical immunology, gastroenterology, dermatology, and hematology clinicians who manage patients with nonadvanced SM. Educational Objectives: Evaluate patients with nonadvanced SM to characterize symptoms, disease burdens, and results from ancillary testing Describe the mechanistic rationale and recent clinical trial evidence for new targeted treatment options in nonadvanced SM Individualize treatment regimens for nonadvanced SM to reflect symptomatology, patient-reported outcomes, and shared clinical decision making
Expiration	Jul 14, 2024
Credits / Hours	0.75
Accreditation	ACCME
Is This Activity Certified for "Live" Credit?	YES
Presenters / Authors / Faculty	Tracy I. George, MD Professor of Pathology University of Utah School of Medicine President and Chief Scientific Officer ARUP Laboratories Salt Lake City, Utah Matthew P. Giannetti, MD Instructor, Harvard Medical School Allergy and Immunology Associate Director Brigham and Women’s Hospital Mastocytosis Center Boston, Massachusetts Anthony P. Fernandez, MD, PhD Assistant Professor of Clinical Medicine, CCLCM Director of Medical Dermatology W.D. Steck Chair of Clinical Dermatology Cleveland Clinic Cleveland, Ohio Matthew P. Giannetti, MD Instructor, Harvard Medical School Allergy and Immunology Associate Director Brigham and Women’s Hospital Mastocytosis Center Boston, Massachusetts Matthew P. Giannetti, MD Instructor, Harvard Medical School Allergy and Immunology Associate Director Brigham and Women’s Hospital Mastocytosis Center Boston, Massachusetts Matthew J. Hamilton, MD Assistant Professor of Medicine Harvard Medical School Lead Gastroenterologist Brigham and Women’s Hospital Mastocytosis Center Boston, Massachusetts
Sponsors / Supporters / Grant Providers	This activity is provided by Global Education Group. (ACCME Credit) This activity is jointly provided by Global Education Group and Integritas Communications. (AANP Credit) This activity is supported by an independent educational grant from Blueprint Medicines Corporation.
Keywords / Search Terms	Integritas Communications nonadvanced systemic mastocytosis, SM, assessment techniques, patient education, targeted therapies, Free CE CME Live CE CME

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