Airing It Out: A Case-Based Conversation on Managing Asthma and Chronic Rhinosinusitis With Nasal Polyps

The educational design of this activity addresses the needs of allergists, clinical immunologists, and other specialist clinicians involved in the management of patients with chronic rhinosinusitis with nasal polyps (CRSwNP) or asthma. Disorders involving inflammation or tissue remodeling in the respiratory tract are responsible for significant patient morbidity, potential mortality, and trem...
Integritas Communications

JAKi in RA Practice: Unpacking the Evidence for Their Use Today and Tomorrow

The Janus kinase (JAK) family of intracellular tyrosine kinases plays a pivotal role in transducing extracellular cytokine signaling, thereby contributing to major processes such as cellular proliferation, homeostasis, and host defense against infection.1 In RA, certain JAK-mediated signaling pathways are dysfunctionally active, leading to enhanced transcription of various proinflammatory genes ...
Integritas Communications

Managing Opioid-Induced Constipation: Translating Guidelines Into Patient Care

Constipation, the most common side effect of chronic opioid therapy, is a constellation of symptoms that includes infrequent or incomplete bowel movements, abdominal pain or bloating, and the need to strain when having a bowel movement.1,2 In addition to constipation-related discomfort, opioid-induced constipation (OIC) produces significant health and quality-of-life burdens.3,4 Poorly managed O...
Integritas Communications

Marching Forward in Atopic Dermatitis: Digging Deep on Shared Decision-Making

Atopic dermatitis is a common, chronic inflammatory disease that manifests primarily in the skin, although research has uncovered potentially deleterious effects in other organ systems throughout the body.1,2 The disease-related physical and biopsychosocial burdens of this condition can have a substantial effect on patient and parent/caregiver quality of life.3,4 Furthermore, people with atopic ...
Integritas Communications

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