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Exploring New Treatment Advances for Acid Sphingomyelinase Deficiency in Adults
STATEMENT OF NEED
Acid sphingomyelinase deficiency (ASMD) is a rare, hereditary lysosomal storage disease with multisystemic manifestations, including splenomegaly, hepatomegaly, interstitial lung disease, dyslipidemia, bone marrow and lymph node involvement, and sometimes neurological and peripheral nerve involvement. While the most severe form of ASMD, infantile neurovisceral ASMD, results in death in early childhood, chronic forms of ASMD have more prolonged survival but are associated w... |
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Supporting Neurodevelopment With Brain-Building Nutrition
The brain is one of the fastest growing organs in infants; by the time infants reach 2 years of age, the brain has nearly doubled in size. During this period of time, neurons proliferate, synapses form, and nerve fibers are myelinated"all processes that require support with optimal nutrition. This material reviews the latest learnings on the ways in which nutrition can influence neurodevelopment. Human milk is rich in key lipids for neurodevelopment, which are encapsulated by the milk fat... |
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