New Data and Clinical Perspectives on the Treatment of Metastatic Hormone-Sensitive Prostate Cancer

STATEMENT OF NEED Prostate cancer is the most common tumor type affecting men in the United States. An estimated 191,930 new cases are diagnosed annually, and 33,330 people die from the disease (ACS, 2020). Most patients with metastatic hormone-sensitive prostate cancer (HSPC) present with relapse after local treatment, while approximately 5% of all prostate cancer patients present with de novo metastatic HSPC (Ng et al, 2020). The five-year overall survival rate for metastatic HSPC remains...
i3 Health

Metastatic Breast Cancer: Enhancing Treatment Tolerability, Adherence, and Patient-Centered Care

STATEMENT OF NEED Breast cancer accounts for approximately 30% of cancer diagnoses among women in the United States and is the second-leading cause of cancer death in this population (ACS, 2019). Although many women benefit from regular screening as well as earlier and improved treatment, approximately 6% present with metastatic disease, and up to 30% with no initial lymph node involvement eventually develop metastatic disease (Siegel et al, 2019; Mortensen et al, 2018). Women with MBC have...
i3 Health

Diagnosis, Treatment and Prevention Therapies in Primary Headache Disorders

ACTIVITY OVERVIEW Primary headache disorders are a major cause of disability and a common reason people seek medical care. However, distinguishing a primary from a secondary headache disorder, as well as among primary headache disorders, is often challenging. Focusing on cluster and migraine, Drs. Jessica Ailani and Stewart Tepper provide criteria and strategies to overcome this challenge in the office setting. Insight is also provided to help guide treatment with evidence-based medications a...
Annenberg Center for Health Sciences at Eisenhower

Keeping Pace With Evolving Treatment Paradigms in Advanced Renal Cell Carcinoma: The Nurse’s View

STATEMENT OF NEED Kidney cancer accounts for approximately 4% of all cancer diagnoses in the United States (ACS, 2020). An estimated 73,750 new cases are reported annually and 14,830 people die of the disease. Renal cell carcinoma, which comprises nearly 90% of all kidney cancers, is characterized by a lack of early warning signs, diverse clinical manifestations, and resistance to radiation and chemotherapy. Due to its often asymptomatic presentation, many patients have advanced disease at ...
i3 Health

Expert Guidance on New Advances in Renal Cell Carcinoma

STATEMENT OF NEED Kidney cancer accounts for approximately 4% of all cancer diagnoses in the United States (ACS, 2020). An estimated 73,750 new cases are reported annually and 14,830 people die of the disease. Renal cell carcinoma, which comprises nearly 90% of all kidney cancers, is characterized by a lack of early warning signs, diverse clinical manifestations, and resistance to radiation and chemotherapy. Due to its often asymptomatic presentation, many patients have advanced disease at ...
i3 Health

Virtual Tumor Board: Optimizing Personalized Care Plans for Patients With Metastatic Breast Cancer

STATEMENT OF NEED Breast cancer accounts for approximately 30% of cancer diagnoses among women in the United States and is the second-leading cause of cancer death in this population (ACS, 2020). Although many women benefit from regular screening as well as earlier and improved treatment, approximately 6% present with metastatic disease, and up to 30% with no initial lymph node involvement eventually develop metastatic disease (Siegel et al, 2020; Mortensen et al, 2018). Women with metastat...
i3 Health

Virtual Tumor Board: Optimizing Personalized Care Plans for Patients With Advanced Soft Tissue Sarcoma

STATEMENT OF NEED Soft tissue sarcomas are a heterogeneous group of malignancies that arise primarily from the mesodermal tissues of the extremities, trunk and retroperitoneum, and head and neck. An estimated 13,130 new cases are diagnosed in the United States annually and 5,350 people die of the disease. Surgical resection is the mainstay of treatment for localized soft tissue sarcoma, with radiation and chemotherapy commonly used as adjuncts. However, nearly 50% of patients will experienc...
i3 Health

Navigating the Recent Rheumatoid Arthritis Guidelines to Achieve Disease Remission and Reduce Patient

Roy M. Fleischmann, MD, discusses the latest evidence for the management of patients with moderate-to-severe rheumatoid arthritis who do not achieve treatment goals with initial disease-modifying anti-rheumatic drug therapy. A key treatment principle emphasized by Dr. Fleischmann is using a treat-to-target approach guided by validated tools for assessing disease activity and patient-reported outcomes. Among the treatment options, Dr. Fleischmann highlights the pharmacology of the latest approv...
Annenberg Center for Health Sciences at Eisenhower

Navigating Advancements in Diagnosis & Treatment of Axial Spondyloarthritis

More than 80% of the population has significant back pain at some point in their life, with 30% of adults in the United States stating they have chronic low back pain at any given time; 5% of whom have inflammatory back pain. Axial spondyloarthritis (axSpA) affects almost 1.5% of patients with inflammatory back pain; however, the majority of individuals suffering with back pain are not being treated by a rheumatologist, which only exacerbates the challenge to diagnose those with axSpA. Dr....
Annenberg Center for Health Sciences at Eisenhower

Research Developments in Atopic Dermatitis

Welcome to this activity focusing on new research related to atopic dermatitis presented as posters at the 2020 virtual annual meetings of the American Academy of Dermatology and the American Academy of Allergy, Asthma, and Immunology. The posters focus on new data related to the use of advanced therapies for atopic dermatitis. Beyond discussing the methods and results of each poster, the faculty, Drs. Steven Feldman and Alan Fleischer, Jr., share their views on the implication of the trial re...
Annenberg Center for Health Sciences at Eisenhower

Immune Thrombocytopenia: Evolving Treatment Paradigms and Patient-Centered Care

STATEMENT OF NEED Immune thrombocytopenia is an acquired immune-mediated disorder defined as a peripheral blood platelet count
i3 Health

Defining Personalized Care Plans in Metastatic Colorectal Cancer

STATEMENT OF NEED Colorectal cancer (CRC) is the third leading cause of cancer death among men and women in the United States. An estimated 145,600 new cases are diagnosed annually and 51,020 people die of the disease. When detected and treated early at a localized stage, the 5-year survival rate is 90%. However, because CRC initially exhibits no symptoms and the use of routine screening is suboptimal, most patients are diagnosed at later stages. Approximately 21% of patients present with m...
i3 Health

Right Patient, Right Treatment, Right Time: Utilizing Early, High-Efficacy Therapies to Improve Outcomes in RRMS

Recent studies have demonstrated the benefits of early and aggressive treatment strategies in reducing disability progression and the frequency of relapses in patients with relapsing remitting multiple sclerosis (RRMS), marking a paradigm shift in the treatment of patients with RRMS. The traditional escalation approach is now often set aside in favor of the more individualized "induction" approach, which utilizes "early and aggressive" treatment with high-efficacy disease-modifying therapies (...
CME Outfitters

Beyond the Old Paradigms: Novel Approaches to the Treatment of Chronic Idiopathic Constipation

Chronic idiopathic constipation (CIC) affects 35 million adults in the United States, making it one of the most common gastrointestinal disorders. Despite the high prevalence, CIC is often underdiagnosed and undertreated, which exacts a functional, psychosocial, and economic toll on patients and their loved ones. The current treatment goal in CIC is multi-symptom relief, but only 16% of patients with CIC are on prescription therapy, and they often only obtain partial relief, with many using la...
CME Outfitters

Giving Shingles Immunization Your Best Shot: Implementing a Shingles Vaccination Protocol in Your Practice

Shingles, or herpes zoster, is a common secondary infection for older patients. Almost all individuals over the age of 50 are latently infected with varicella zoster virus (VZV) and therefore are at risk of developing shingles with reactivation of latent VZV. Individuals who develop shingles often experience debilitating postherpetic neuralgia (PHN), secondary skin infections, eye problems, or neurologic conditions including an increased risk of stroke. Despite the existence of vaccines, th...
CME Outfitters

Retooling for Modern Management of Progressive MS: An Interactive, Case-Based Activity

The approval of ocrelizumab for primary progressive multiple sclerosis (PPMS) was groundbreaking, and more recently the MS community bore witness to another major breakthrough in MS management when siponimod was approved for secondary progressive MS (SPMS). Additionally, new investigational agents such as MD1003 (high-dose biotin) and masitinib are also being evaluated for treatment of PPMS, and clinical data for both show promise for patients with SPMS. However, despite these advances, stu...
CME Outfitters

Looking Ahead: Integrating Emerging Therapies and Tools in Early-Stage Alzheimer's Disease

Alzheimer's disease (AD), a heterogeneous, neurodegenerative condition with an insidious onset and slow progression, is the leading cause of disability and morbidity as well as the sixth-leading cause of death in the United States. Diagnosing AD is often complicated due to its varied clinical symptomatology and unknown etiology, and currently only symptomatic therapies are available. Recent clinical trials investigating disease-modifying therapies (DMTs) that could slow or reverse the progr...
CME Outfitters

Hitting the Target with IL-23 Inhibitors in Psoriatic Arthiritis

Psoriatic arthritis (PsA) is a chronic, inflammatory, musculoskeletal disease with a significant impact on quality of life and functional ability. Despite the data showing the overall impact of PsA, delays in diagnosis are common, which can lead to long-term joint damage and functional disability. In this CME Outfitters Live and OnDemand activity, expert faculty will focus on assessment, treatment, and management strategies to provide patients with the best treatment aligned with evolving e...
CME Outfitters

Keeping the Beat: Screening and Management of High-Risk Patients with Non-Valvular Atrial Fibrillation

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, projected to affect 12 million Americans by 2030. However, a significant number of AF cases, particularly non-valvular atrial fibrillation (NVAF) remain undiagnosed, putting patients at risk for severe cardiovascular (CV) complications, including increased risk of stroke. It is imperative that clinicians identify the symptomatology of AF and effectively diagnose NVAF, as these complications can potentially be avoided by ...
CME Outfitters

Targeted Therapy for HER2 and HER3-Positive Breast Cancer: Navigating the Evolving Treatment Landscape

Statement of Need Breast cancer (BC) is a heterogeneous disease with human epidermal growth factor receptor 2 (HER2) overexpression and/or amplification observed in 20%-30% of cases. HER2-positive (+) BC correlates with poor clinical outcomes unless appropriately treated with targeted therapy. Despite significant therapeutic advances, many patients experience disease progression with resistance to targeted agents developing over the course of treatment. This CME Outfitters Live and OnDe...
CME Outfitters

Tumor-induced Osteomalacia (TIO): Diagnosis and Management

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic condition commonly characterized by bone pain, muscle weakness and fractures. These tumors secrete excess fibroblast growth factor 23 (FGF23) which inhibits the sodium phosphate renal co-transporters and suppresses 1α hydroxylase activity, thereby decreasing renal reabsorption and increased urinary phosphate excretion. As a result, unexplainable hypophosphatemia with a variety of musculoskeletal abnormalities are the most common sympto...
CheckRare

Neuroendocrine Tumors (NETs) Research Highlights from ENDO 2020

Although the 2020 Endocrine Society’s annual meeting (ENDO 2020) did not take place as scheduled, abstracts, including new information and data on neuroendocrine tumors (NETs) were published. This CME activity highlights the latest information about NETs from ENDO 2020 and provides expert analysis of its clinical relevance for busy members of the care team in order to help them care for patients with these rare diseases.
CheckRare

Exploring Novel Treatment Strategies for Metastatic Colorectal Cancer

STATEMENT OF NEED Colorectal cancer (CRC) is the third leading cause of cancer death among men and women in the United States. An estimated 145,600 new cases are diagnosed annually and 51,020 people die of the disease. When detected and treated early at a localized stage, the 5-year survival rate is 90%. However, because CRC initially exhibits no symptoms and the use of routine screening is suboptimal, most patients are diagnosed at later stages. Approximately 21% of patients present with m...
i3 Health

Clinical Updates and Expert Guidance in Prostate Cancer

STATEMENT OF NEED Prostate cancer is the most common tumor type affecting men in the United States, with an estimated 174,650 new cases reported each year. Typically, androgen deprivation therapy is administered for progressive disease. However, castration resistance or unresponsiveness to androgen deprivation therapy or to antiandrogens frequently develops over time. The transition from castration-sensitive to castration-resistant disease has yet to be understood and represents a significa...
i3 Health

Virtual Tumor Board: Diagnosis and Management of Myelodysplastic Syndromes

STATEMENT OF NEED Myelodysplastic syndromes (MDS) are a group of heterogeneous hematopoietic disorders derived from an abnormal multipotent progenitor cell, characterized by ineffective hematopoiesis, bone marrow failure, and peripheral blood cytopenias. Survival in MDS ranges from a median of 5.3 years in lower-risk patients to as little as 0.8 years in higher-risk patients. Mortality is usually a result of infection, hemorrhage, and/or iron overload secondary to red blood cell transfusion...
i3 Health

Multiple Myeloma: Enhancing Treatment Tolerability, Adherence, and Patient-Centered Care

STATEMENT OF NEED Multiple myeloma (MM) is a B-cell neoplasm characterized by aberrant expansion of plasma cells within the bone marrow and extramedullary sites (eg, cortical bone). Approximately 32,270 new cases of MM are diagnosed in the United States annually and 12,830 people die of the disease. Although the tumor cells remain primarily within the bone marrow, they can cause a number of complications, including localized bone destruction, anemia, decreased immunity to infection, and kid...
i3 Health

Mucopolysaccharidoses (MPSs) Highlights from WORLDSymposium 2020

At WORLDSymposium 2020, new information and data were presented on Mucopolysaccharidoses (MPSs), a group of genetic lysosomal disorders. This CME activity highlights the latest information about MPSs from WORLDSymposium and provides expert analysis of its clinical relevance for busy members of the care team in order to help them care for patients with these rare diseases.
CheckRare

Gaucher Disease Highlights from WORLDSymposium 2020

At WORLDSymposium 2020, new information and data were presented on Gaucher disease, a rare lysosomal storage disorder. This CME/CNE activity highlights the latest information about Gaucher disease from WORLDSymposium and provides expert analysis of its clinical relevance for busy members of the care team in order to help them care for patients with this rare disease.
CheckRare

Fabry Disease Highlights from WORLDSymposium 2020

At WORLDSymposium 2020, new information and data were presented on Fabry disease, a rare lysosomal storage disorder. This CME/CNE activity highlights the latest information about Fabry disease from WORLDSymposium and provides expert analysis of its clinical relevance for busy members of the care team in order to help them care for patients with this rare disease.
CheckRare

@MondayNightIBD OnDemand: Addressing the Cases That Challenge Your Practice

Statement of Need Gastroenterologists are trailblazers in health care social media, and #MondayNightIBD (#MNIBD) has harnessed that energy to establish gastroenterologists as not just social media influencers but as clinical practice influencers as well. #MNIBD is not just a weekly social media conversation - it is an international platform that is moving the field forward by crowdsourcing the expertise of leading inflammatory bowel disease (IBD) experts, community clinicians, and patients ...
CME Outfitters

Navigating the New Psoriasis Guidelines: Implications for Clinical Practice

Statement of Need: The American Academy of Dermatology (AAD) and the National Psoriasis Foundation (NPF) have recently released new joint guidelines that outline best practices for the management of psoriasis (PsO) with biologics, the need for awareness and attention to comorbidities, and guidelines for pediatric PsO treatment. Clinicians must ensure that they are aware of these guidelines and of strategies to incorporate them into clinical practice, including the integration of biologic ther...
CME Outfitters

At-Risk Patients Hidden in Plain Sight: Real-World Strategies for Screening and Treating Hepatitis B Virus

Statement of Need Chronic hepatitis B virus (HBV) remains a global epidemic, resulting in significant morbidity and mortality. In 2015, there were 257 million people worldwide infected with HBV. In 2016, only 10.5% were diagnosed, with only 16.7% receiving treatment, and without intervention, there are 19 million deaths anticipated by the end of 2020. These numbers are startling as they exist despite the availability of effective treatment, and this is in part due to lack of clinician knowl...
CME Outfitters

A Deeper Dive into NASH Diagnosis and Treatment: An Augmented Reality Experience

Statement of Need Obesity and diabetes are on the rise, leading to an increased prevalence of non-alcoholic fatty liver disease (NAFLD), which in some cases may progress to non-alcoholic steatohepatitis (NASH). NAFLD effects approximately 30% of the U.S. population, with NASH effecting about 5%. NASH comes with a significant risk of progression to advanced liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Disease models project that the number of individuals with end-stage live...
CME Outfitters

Nursing Management of Myelofibrosis: Controlling Symptoms and Optimizing Patient Quality of Life

STATEMENT OF NEED Myeloproliferative neoplasms are a heterogeneous group of hematopoietic disorders that includes myelofibrosis, polycythemia vera (PV), and essential thrombocythemia (ET). These malignancies affect approximately 13,000, 134,000, and 148,000 individuals in the United States, respectively. As symptoms do not typically manifest in early stages, patients with MPNs often present with advanced disease. The presence of comorbidities precludes most from potentially curative allogen...
i3 Health

Addressing the Burden of Psoriatic Arthritis: Moving Beyond the Joint

Philip J. Mease, MD, and Alexis R. Ogdie-Beatty, MD, review the pathogenesis and a wide spectrum of clinical features, manifestations, and comorbidities of psoriatic arthritis; talk about classification criteria for PsA and different patient-reported and provider-assessed outcome measures; and discuss treatment recommendations and strategies, as well as various types of current and emerging therapies. Finally, they highlight some of the key issues and challenges of the management of PsA throug...
Annenberg Center for Health Sciences at Eisenhower

Shifting Focus: Individualizing Preventive Therapy for Hereditary Angioedema

William Lumry, MD, FACAAI, discusses the genetic component of HAE and differences among the types of HAE. This activity also includes several eye-opening video clips from patients with HAE who describe how it affects their daily lives. Content Areas: • Burden of disease • Clinical presentation, features • Causes and types • Diagnosis and screening • Approaches to treatment • Preventive treatment • Comprehensive treatment
Annenberg Center for Health Sciences at Eisenhower

Optimizing Personalized Care Plans for Patients With Advanced Non-Small Cell Lung Cancer

STATEMENT OF NEED An estimated 228,150 new cases of lung cancer are reported in the United States annually, and 142,670 people die of the disease. The major subtypes are non-­small cell (84%) and small cell (13%). Most patients with lung cancer are diagnosed at a locally advanced or metastatic stage, making systemic therapy the cornerstone of management. Although 70% of patients receiving first-line classical doublet chemotherapy demonstrate clinical benefit, most develop progressive disea...
i3 Health

PILOTforPulmonary 2019: Data, Insights & Practice

This education provides the opportunity to learn the latest in the management of patients with IPF/ILD. Summaries or abstracts from recent pulmonary meetings will be presented followed by video discussions by expert faculty regarding the implications on the management of patients with IPF/ILD. Skills can then be applied in an interactive case where the learner is challenged to make decisions for the patient.
The France Foundation

New Thinking, New Strategies in Advanced Urothelial Carcinoma

STATEMENT OF NEED Bladder cancer is the sixth most common malignancy among adults in the United States. Approximately 80,470 new cases are diagnosed annually and 17,670 people die of the disease. More than 90% of patients with bladder cancer have the urothelial carcinoma subtype, which has a high rate of recurrence whether it is low or high grade. Approximately half of all bladder cancers are diagnosed in situ, for which the 5-year relative survival rate is 95%. For tumors diagnosed as a lo...
i3 Health

Food Allergy: From Primary Prevention to Treatment and Intervention Online

This online offering includes 19 videos of lectures and panel discussions on the diagnosis and management, specific syndromes, treatment, and research and prevention of food allergy. The videos were recorded at a live course that took place at a live AAAAI course held in early September, 2019. The intent of the videos is to allow learners to increase their knowledge related to the diagnosis and management of food allergic patients. It highlights the latest evidence related to food allergie...
American Academy of Allergy, Asthma & Immunology

Conversations from the World of Allergy: Podcast Episodes for Credit

This podcast features interviews on a wide variety of allergy/immunology topics. It is our hope that the conversations provide evidence-based information that is useful to clinicians, researchers and patients, alike. Some episodes are available for CME credit. All podcast episodes are available at https://www.aaaai.org/professional-education-and-training/podcasts
American Academy of Allergy, Asthma & Immunology

Lifestyle Medicine: Tools for Promoting Healthy Change - LIVE STREAMING

State-of-the-Art Approaches to Help Patients Initiate and Sustain Health-Promoting Behaviors Lifestyle Medicine will be held online this year, using live streaming, electronic Q&A, and other remote learning technologies. Overview This immersive two-day course offers state-of-the-art strategies to guide patients to healthier lives. Education includes evidence-based strategies, tools and techniques to effect healthier changes in patients (and ourselves), including nutrition, exercise, slee...
Harvard Medical School

16-Night New Zealand CME AWAY® Cruise

Auckland, New Zealand • Bay Of Islands, New Zealand • Kingston, Norfolk Island, New Zealand • New Plymouth, New Zealand • Milford Sound, New Zealand • Dunedin, New Zealand • Akaroa, New Zealand • Wellington, New Zealand • Nelson, New Zealand • Picton, New Zealand • Napier, New Zealand • Tauranga, New Zealand
CME AWAY by Sea Courses

7-Night Jamaica CME AWAY® Resort - Pearls for Managing Different Kinds of Arthritis, Sleep Disorders & Communicating with Patients

The all-new Sandals South Coast is the perfect combination of European civility in anall-beachfront resort. From all-new Over-the-Water Bungalows, an overwater bar, and a romantic Over-the-Water Chapel, Sandals South Coast brings guests closer than ever to the water. Set on a 2-mile stretch of Jamaica's south coast's most pristine white-sand beach and nestled within a 500-acre nature preserve, this spectacular seaside oasis features three distinctive European Villages. Relax by one of three po...
CME AWAY by Sea Courses

Primary Care: Pediatric Emergency Medicine Review

We get it. Some people are ready to travel and some people are not. The choice should be yours. At CME Seminars, all of our seminars are both live events and streamed as a webinar. You have your choice to attend using either option. We offer that same choice to our speakers. If a speaker attends remotely, the session will still be live and in real time. When you sign up for a seminar, you can choose the other option if you change your mind and receive a no hassle refund or upcharge for th...
CME Seminars

Primary Care Medicine: Family Medicine / Internal Medicine

We get it. Some people are ready to travel and some people are not. The choice should be yours. At CME Seminars, all of our seminars are both live events and streamed as a webinar. You have your choice to attend using either option. We offer that same choice to our speakers. If a speaker attends remotely, the session will still be live and in real time. When you sign up for a seminar, you can choose the other option if you change your mind and receive a no hassle refund or upcharge for th...
CME Seminars

Hospitalist / Internal Medicine Review

We get it. Some people are ready to travel and some people are not. The choice should be yours. At CME Seminars, all of our seminars are both live events and streamed as a webinar. You have your choice to attend using either option. We offer that same choice to our speakers. If a speaker attends remotely, the session will still be live and in real time. When you sign up for a seminar, you can choose the other option if you change your mind and receive a no hassle refund or upcharge for th...
CME Seminars

36th Annual UCLA Intensive Course in Geriatric Medicine and Board Review.

The 36th Annual UCLA Intensive Course in Geriatric Medicine & Board Review aims to enhance your knowledge of essential topics in primary and specialty care of your aging patients. Led by Zaldy Tan, MD, MPH, this CME program will help you to keep pace with the latest developments and to prepare for certification or re-certification exams in geriatric medicine offered by the American Board of Internal Medicine (ABIM) and the American Board of Family Practice (ABFP).
CMEinfo

RME Hot Seat: Immunotherapy for Multiple Myeloma

The number and type of treatments for multiple myeloma continue to expand rapidly. The emergence of several new immunotherapy options holds particular promise for patients with relapsed/refractory myeloma, but effectively integrating these approaches into practice remains a significant challenge. Developed for oncology nurses and advanced practitioners, this RME Hot Seat provides a virtual Q&A with a panel of experts who field a range of questions on the use of antibody-based therapies, bis...
Purdue University; Multiple Myeloma Research Foundation; RedMedEd

The C. diff Returns: The Latest Strategies to Mitigate Recurrence.

Originally presented at a virtual symposium following the IDWeek™ 2020, Paul Feuerstadt, MD, Kevin W. Garey, PharmD, and Krishna Rao, MD, discuss guideline-directed prevention and treatment of recurrent Clostridium difficile (C. diff). Other discussion topics include risk factors for C. diff recurrence as well as antimicrobial interventions to reduce recurrence and improve outcomes.
ACHL

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