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Neuroinflammation in Alzheimer’s Disease: Implications for Early Detection and Treatment
Alzheimer’s disease (AD) is an irreversible, age-related neurodegenerative disorder characterized by a gradual decline in understanding, memory, and ability to perform activities of daily living. With the recent approval of novel AD treatments and the evolving therapeutic landscape, it is imperative for clinicians to stay informed on the current issues surrounding AD. This CE program "Neuroinflammation in Alzheimer’s Disease: Implications for Early Detection and Treatment" aims t... |
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Neuroinflammation in Alzheimer’s Disease: Implications for Early Detection and Treatment
Alzheimer’s disease (AD) is an irreversible, age-related neurodegenerative disorder characterized by a gradual decline in understanding, memory, and ability to perform activities of daily living. With the recent approval of novel AD treatments and the evolving therapeutic landscape, it is imperative for clinicians to stay informed on the current issues surrounding AD. This CE program "Neuroinflammation in Alzheimer’s Disease: Implications for Early Detection and Treatment" aims t... |
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Psoriasis Prime Time: TYK Inhibition in Hard-to-Treat Psoriasis
Target Audience
This activity has been designed to address the educational needs of dermatologists, dermatology nurse practitioners, and PAs. It may also be of benefit to primary care clinicians, rheumatologists, and other healthcare practitioners who are interested in the treatment of psoriasis.
Program Overview
In this edition of Psoriasis Prime Time, the faculty reviews the use of allosteric tyrosine kinase 2 (TYK2) inhibitors in the treatment of hard-to-treat psoriasis, including the ... |
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Can You Diagnose this Patient with Edema, Pain, Abdominal Swelling, and/or Fatigue?
When your patient presents with symptoms such as edema, fatigue, and abdominal pain, what might you first suspect and can you reach the right diagnosis? Put your diagnostic skills to the test! In just 15 minutes, navigate through real-world cases and upon completion, hear faculty insights on the implications of your decisions along with rationales for appropriate next steps to aid in making a final diagnosis, as well as evidence-based treatment strategies. Apply the latest scientific evidence ... |
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9th Annual Internal Medicine in Primary Care Conference
Prepare to embark on an extraordinary voyage of discovery and rejuvenation aboard the Celebrity Edge, where the 9th Annual Internal Medicine in Primary Care Conference awaits amidst the awe-inspiring landscapes of Alaska. From July 25 to August 1, 2025, immerse yourself in the natural splendor of the Inside Passage as you sail through pristine fjords, past towering glaciers, and alongside majestic wildlife. This unique cruise offers a perfect blend of educational enrichment and leisurely explo... |
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Artificial Intelligence in Radiology (Streaming Online & USB Drive)
Artificial Intelligence in Radiology will provide imagers of all experience levels with the introductory information and foundational skills necessary to thrive in a future impacted by AI integrated healthcare. Developed in collaboration with Artificial Intelligence Medical Education (AiME), this activity is designed to demonstrate AI’s radiology applications, its potential to enhance clinical practice and its limitations. As such, this practical and clinically relevant overview will detail... |
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Optimizing Early Nutrition for Long-Term Benefits
Sharon Donovan, PhD, RD, and Michael Georgieff, MD, review what is currently known about the influence of nutrition during the first 1,000 days of growth and development. Human milk"the model for optimal nutrition"is discussed, including its nutritive and nonnutritive components, how it functions as a dynamic biological system, and the latest breastfeeding guidelines. The implications of suboptimal early nutrition are addressed, along with the role of pediatric clinicians in providin... |
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A Primer on IgE-Mediated Food Allergies, With Drs. Kelly Cleary and Barbara Yawn
In this CE podcast, developed in collaboration with Food Allergy Research & Education (FARE), experts review the pathophysiological underpinnings of IgE-mediated food allergies and discuss the importance of shared decision-making and interdisciplinary approaches to optimize patient care. |
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Advances in the Management of IgE-Mediated Food Allergies, With Drs. Kelly Cleary and Robert Wood
In this podcast, expert clinicians will discuss the efficacy and safety of traditional and emerging treatments as well as evidence-based guidance for managing patients with immunoglobulin E (IgE)-mediated food allergies. |
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Beyond Avoidance: IgE-Mediated Food Allergies " Therapeutic Innovations to the Rescue
In the United States, food-induced allergic reactions are the leading cause of anaphylaxis in hospital emergency departments. Among these, immunoglobulin E (IgE)-mediated food allergies are the most common, and they pose significant risks, including cardiac arrest and respiratory failure. Traditionally, treatment options for IgE-mediated food allergies have been primarily limited to food avoidance and anaphylaxis prevention. However, recent years have brought the FDA approval of the first oral... |
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Establishing Frameworks for Precision Medicine in NTRK Fusion-Positive Advanced Solid Tumors
Despite significant advancements over the past decade, significant unmet needs persist for patients with NTRK-positive locally advanced or metastatic solid tumors. In addition, there is ongoing debate about the importance of testing for genomic alterations in rare cancers, or those that rarely occur in common cancers. However, evolving molecular testing procedures and emerging therapeutic options targeting NTRK fusions offer new pathways for the detection and treatment of these cancers. To he... |
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Management of Metastatic Colorectal Cancer
Stacey Cohen, MD, explores the significance of molecular profiling and tumor markers in personalizing immunotherapy for metastatic colorectal cancer. She also delves into the evolving landscape of targeted therapies, discussing the nuances and considerations of different options to optimize patient outcomes. |
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Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 1
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 2
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). Multicancer early detection (MCED) is an emerging form of blood-based testing that utilizes cancer biomarkers in the blood to screen for multiple cancers simultaneously (ACS, 2024). Currently, numerous clinical trials are investiga... |
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Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 3
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States (ACS, 2024; Pinsky & Berg, 2012; USPSTF, 2024). Multicancer early detection (MCED) is a novel form of blood-based ca... |
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Podcast - Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 1
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Podcast - Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 2
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Podcast - Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 3
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Recognizing and Confirming Potential ATTR in Your Patients
Target Audience
This activity is designed to meet the educational needs of physicians, allied health practitioners, and students interested in complex cardiovascular and thoracic conditions and those who care for patients with ATTR.
Program Overview
This activity will cover early diagnosis and intervention for transthyretin amyloidosis (ATTR), which is critical, yet does not occur, typically as a consequence of the rarity and heterogeneity of the disease and limited awareness on the part ... |
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ASCVD Clinical Research Updates Targeting Residual Inflammation in Patients with ASCVD and CKD
Emerging evidence and scientific advancements are revealing pathophysiologic mechanisms correlated with systemic inflammation and the development of atherosclerotic cardiovascular disease (ASCVD). Patients with chronic kidney disease (CKD) are at high risk for developing ASCVD. Novel anti-inflammatory therapies are showing efficacy at reducing inflammation and development of ASCVD, and are adding to the treatment options beyond the usual lipid-lowering agents. As new clinical evidence and tar... |
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Bunion-Like Toes and Tumor Like Swellings " Recognize FOP and Improve Patient Outcomes in the Era of Disease Specific Therapy
Target Audience
This activity is designed to meet the educational needs of healthcare providers in pediatrics, primary care, oncology, surgery, radiology, acute care, emergency medicine, rheumatology, and infectious disease.
Program Overview
Bunion-like toes present at birth and tumor-like swellings in a young child are diagnostic signs of fibrodysplasia ossificans progressive (FOP), a disease with recent advances made in therapy. Upon completion of the course, learners should be able to ... |
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Podcast: Multidisciplinary Task Force and Position Statement: Mitigating Disease Burden and Health Care Disparities in Relapsed/Refractory Multiple Myeloma
STATEMENT OF NEED
With the complex and rapidly evolving treatment landscape of multiple myeloma, it is vital that clinicians not only understand factors for informing selection of current and emerging combination and sequential therapeutic strategies, but also employ interdisciplinary strategies for reducing disparities in relapsed/refractory multiple myeloma care. The development of novel therapeutic options has significantly improved treatment outcomes for patients with relapsed/refractor... |
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Bridging the Health Gaps in Hereditary Angioedema: Demystifying Disparities, Enhancing Quality of Life, and Implementing Effective Prophylactic Solutions
Hereditary angioedema (HAE) is a rare, life-threatening disorder characterized by recurrent, unpredictable episodes of bradykinin-induced swelling. In this presentation, Dr. Marc Reidl, Clinical Director of the US Hereditary Angioedema Association (HAEA) Angioedema Center, reviews multiple underrecognized factors that contribute to health disparities among patients with HAE, including delays in diagnosis and multifaceted differences among racial and ethnic groups, socioeconomic status levels, ... |
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Ace the Case: A 15-Year-Old Girl With a Remote History of Rash While Taking Amoxicillin
This educational activity will utilize a case study to discuss a 15-year-old girl with a remote history of a rash while taking amoxicillin. |
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Hypertrophic Cardiomyopathy: Unmasking Disparities and Forging a Path to Equitable Care
This comprehensive continuing education (CE) monograph delves into the complexities of HCM, an autosomal dominant genetic disorder marked by increased left ventricular hypertrophy. This condition can lead to significant health complications, such as heart failure, arrhythmias, stroke, and sudden cardiac death. Despite the impact of HCM on patient health and well-being, a gap persists in the understanding of the racial/ethnic and gender-based disparities among healthcare professionals. This gap... |
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Best of ACTHIV® 2024: Beyond Viral Suppression: How Addressing Mental Health Directly Reduces Morbidity and Mortality in People with HIV
Description
Selected by attendees and the program planning committee as one of the best sessions of the ACTHIV® 2024 conference for the frontline HIV care team, this activity will focus on identifying causes of death that are direct outcomes of poor mental health among PWH, and provide guidance for the care team to better enable them to address mental health problems as a component of all HIV-related prevention, care and treatment approaches.
Learning Objectives
Identify three ca... |
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Chronic Rhinosinusitis with Nasal Polyps Navigating New Pathways to Better Patient Outcomes
Chronic inflammatory diseases of the upper and lower airways, especially CRSwNP and asthma, have been tied to significant risks and burdens for affected patients and frequently require close coordinated multidisciplinary care. Targeted agents designed to interrupt inflammatory cytokine signaling have been examined in clinical trials and evidence suggests these options can provide a range of benefits in patients with CRSwNP and related comorbidities. During this interactive activity, expert fac... |
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Inherited Retinal Diseases: Navigating the Future of Diagnostics and Emerging Therapies
The differential diagnosis and workup of a suspected inherited retinal disease (IRD) can be challenging, requiring the expertise of the multidisciplinary healthcare team. Guidelines released in 2022 by the American Academy of Ophthalmology provide recommendations and clinical genetic assessments for patients with IRDs. Genetic counseling is essential to help patients understand the genetic test results, their implications for prognosis, family planning, and therapeutic decisions. Genetic testi... |
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Patient Point of View: PDE4 Inhibitors for the Treatment of Adult Plaque Psoriasis
Psoriasis is a chronic, immune-mediated inflammatory skin disorder that significantly impacts affected individuals’ quality of life. The most common subtype is plaque psoriasis, characterized by erythematous to violaceous plaques covered with scales. Due to the substantial symptom burden of plaque psoriasis and challenges surrounding medication tolerability and adherence, innovative treatment options are needed. Phosphodiesterase-4 (PDE4) inhibitors, which play a key role in the inflammatory... |
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Epstein-Barr Virus-Positive Post-Transplant Lymphoproliferative Disorders: Addressing Unmet Needs with Emerging Therapies
In this Hematology Dialogues, Epstein-Barr Virus-Positive Post-Transplant Lymphoproliferative Disorders: Addressing Unmet Needs with Emerging Therapies, participants will learn about the epidemiology and burden of Epstein-Barr Virus-positive (EBV+) and post-transplant lymphoproliferative disorders (PTLD), differentiate between current and emerging prognostic scoring systems for EBV+ and PTLD to inform treatment decisions, and evaluate the latest clinical evidence of emerging treatment options ... |
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Thyroid Eye Disease: Unmasking and Taming What’s in Disguise
Thyroid eye disease (TED) is a complex autoimmune-mediated inflammatory disorder of the orbit that is associated with a spectrum of signs and symptoms and varying levels of severity. Early diagnosis and initiation of appropriate treatment are imperative for preventing progression to severe disease and potential vision loss. However, diagnosis can be challenging. Traditional treatments for TED, such as steroids, radiotherapy, and surgery, all relieve symptoms but do not alter the course of dise... |
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Overcoming the Hurdles: Advances in the Management of Hemophilia
In this fast-moving, 1-hour accredited activity, Craig Kessler, MD, and Guy Young, MD, share their thoughts and experience with clotting factor concentrates, recombinant factor, factor VIII mimetics, rebalancing agents, and gene therapies. The safety and efficacy of late-phase investigational products are also discussed as these agents have the potential to address unmet needs and further transform patient care. |
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Introduction to Emergency Medicine Ultrasound - Live Course
The Introduction to Emergency Medicine Ultrasound Live Training Course provides participants a strong foundation to perform the core emergency medicine ultrasound applications as outlined in the most recent ACEP ultrasound practice guidelines.
This course is taught by leading emergency medicine ultrasound experts and incorporates comprehensive lectures, interactive case presentations, and extensive hands-on scanning sessions. All hands-on scanning sessions feature a 3:1 participant to exper... |
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Introduction to Critical Care Ultrasound - Live Course
The Introduction to Critical Care Ultrasound Live Training Course provides participants a strong foundation to perform the core critical care ultrasound applications as outlined in the most ACEP ultrasound practice guidelines.
This course is taught by leading critical care and emergency medicine ultrasound experts and incorporates comprehensive lectures, interactive case presentations, and extensive hands-on scanning sessions. All hands-on scanning sessions feature a 3:1 participant to expe... |
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Solving the TED Puzzle: Answering Your Questions on Diagnosis to Decision-Making
Thyroid eye disease (TED) is a complex, autoimmune-mediated, inflammatory disorder of the orbit that presents with a range of symptoms, including ocular pain, dysmotility, and changes in ocular structure and function. The disease severely impacts patients' quality of life, often resulting in persistent discomfort, altered appearance, and impaired vision even after the acute phase subsides. Traditional treatments such as steroids, radiotherapy, and surgery, do not alter the disease's ... |
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Patient‐Centered GA Care: A Synergistic Approach to Optimize Management
The recent FDA approval of 2 novel therapies for the management of patients with geographic atrophy (GA) secondary to age-related macular degeneration has further reenforced the necessity for early GA diagnosis to limit progression. Advances in imaging technologies now provide tools for better detection and characterization of GA, along with biomarkers to monitor progression over time. Optometrists, as front-line eye healthcare providers, play a critical role in the timely diagnosis, managemen... |
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Opportunities with Novel Therapies to Treat the Entire Spectrum of Schizophrenia Symptoms
Available antipsychotic therapies for schizophrenia are effective in treating positive symptoms of schizophrenia yet significant unmet needs remain, including therapies that (1) are more effective in reducing negative and cognitive symptoms of schizophrenia; 2) have improved tolerability and adherence rates; and (3) that are effective in treating refractory schizophrenia. Fortunately, the schizophrenia treatment landscape is poised to change dramatically, offering new opportunities for patient... |
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Advanced Emergency Medicine Ultrasound - Live Course
The Advanced Emergency Medicine Ultrasound Live Training Course is designed to build on the knowledge base of experienced emergency medicine and critical care ultrasound professionals using the most up-to-date ACEP advanced ultrasound topics.
This course is taught by leading emergency medicine & critical care ultrasound experts and incorporates comprehensive lectures, interactive case presentations, and extensive hands-on skills training. All hands-on sessions feature a 3:1 participant ... |
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Advanced Critical Care Ultrasound - Live Course
The Advanced Critical Care Ultrasound Live Training Course is designed to build on the knowledge base of experienced emergency medicine and critical care ultrasound professionals using the most up-to-date ACEP advanced ultrasound topics.
This course is taught by leading emergency medicine & critical care ultrasound experts and incorporates comprehensive lectures, interactive case presentations, and extensive hands-on scanning sessions. The hands-on scanning sessions feature a 3:1 parti... |
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Advances in Recurrent/Metastatic Nasopharyngeal Carcinoma: Immunotherapy and Biomarkers
Target Audience
This activity was developed for medical oncologists, head and neck surgeons, radiation oncologists, physician associates, nurse practitioners, nurses and pharmacists involved in the care of patients diagnosed with metastatic nasopharyngeal carcinoma (NPC).
Program Overview
Greater understanding of the tumor microenvironment of nasopharyngeal carcinoma (NPC) has led to the introduction of immunotherapy into the NPC treatment landscape. Incorporating immunotherapy has change... |
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The Retina Radar With Dr. Arshad Khanani on DR, GA, New Mechanisms, and Noninvasive Treatments
Retinal diseases are a leading cause of global vision impairment, driven by an increasing prevalence and the need for more effective treatment. Although clinical trials have shown promising results for various therapies, real-world application often yields less impressive outcomes due to factors like under-treatment and patient non-adherence. New and emerging therapies, particularly for conditions like diabetic macular edema (DME), diabetic retinopathy, and geographic atrophy (GA) secondary to... |
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Obesity Forum® FAQs: A Podcast Series
Obesity is an increasingly prevalent, chronic condition associated with substantial risks of morbidity and mortality. It is also a risk factor for some of the leading causes of preventable death, including cardiovascular disease, stroke, type 2 diabetes mellitus, sleep apnea, gallbladder disease, osteoarthritis, and certain types of cancer. The 12th Annual Obesity Forum was a 2-part series that provided health care professionals with guidance on the appropriate use of therapies as well as stra... |
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Cleveland Clinic Hospital Medicine
Cleveland Clinic Hospital Medicine features a comprehensive review of the most common and relevant conditions seen in the inpatient setting. A globally renowned faculty addresses the application of new evidence, interprets current guidelines and provides management strategies which can improve the quality of medical care. All physicians, nurses and physician assistants treating hospitalized patients will benefit from this thoughtful assessment of best practices in this critical area of medici... |
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New Guidelines, Emerging Treatments, and Unexpected Patients: Understanding the Challenges of PAH
Target Audience
This activity is designed for nurse practitioners, nurses, and physician assistants who manage patients with or at risk for PAH.
Program Overview
It is a deadly disease and there’s still no cure, but with treatment, survival for patients with pulmonary arterial hypertension (PAH) can be significantly extended. Although rare, nurse practitioners are likely to encounter this cardiopulmonary disorder throughout their careers, and need to be familiar with the multiple dru... |
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Pre-Hospital Ultrasound - Blended Course
Pre-hospital ultrasound can be a valuable tool to rapidly diagnose a variety of conditions associated with trauma and/or critically ill patients. Pre-Hospital focused evaluation of the heart, lungs, and abdomen can provide a rapid and safe method to improve the time to diagnose and/or treat these patients resulting in increased patient safety, satisfaction, and over-all improved patient outcomes in time-sensitive situations.
The Pre-Hospital Ultrasound Blended Training Course is specificall... |
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Ultrasound Guided Vascular Access - Blended Course
The Ultrasound Guided Vascular Access Blended Training Course is planned in accordance with the current Agency for Healthcare Research and Quality (AHRQ) and ACEP guidelines and provides participants a strong foundation to perform central and peripheral line techniques in an emergency setting. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading emergency medicine ultrasound experts ... |
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Introduction to Emergency Medicine Ultrasound - Blended Course
The Introduction to Emergency Medicine Ultrasound Blended Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the core and advanced ultrasound applications as outlined in the ACEP and ACGME ultrasound practice guidelines. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online co... |
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POCUS for Family Medicine - Blended Course
The POCUS for Family Medicine Ultrasound Blended Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the core ultrasound applications as outlined in the AAFP/ACEP ultrasound practice guidelines. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading emergency medic... |
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POCUS for Internal Medicine - Blended Course
The POCUS for Internal Medicine Ultrasound Blended Training Course is intended for any medical professional involved with performing point-of-care ultrasound (POCUS) examinations and provides participants a strong foundation to perform the core ultrasound applications as outlined in the AAFP and ACEP ultrasound practice guidelines. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading emergency med... |
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Ultrasound Guided Nerve Blocks in Emergency Medicine Applications - Blended Course
The Ultrasound-Guided Nerve Blocks for Emergency Medicine Blended Training Course is designed for Emergency Medicine Physicians seeking to integrate ultrasound-guided nerve blocks for pain management, or procedural applications into their clinical practice. It is the position of American College of Emergency Physicians (ACEP) that Ultrasound-guided nerve blocks are a core skill which emergency physicians are capable of providing to patients. Ultrasound-guided nerve blocks will soon be a requir... |
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