Keeping Pace With Evolving Treatment Paradigms in Advanced Renal Cell Carcinoma: The Nurse’s View

STATEMENT OF NEED Kidney cancer accounts for approximately 4% of all cancer diagnoses in the United States (ACS, 2020). An estimated 73,750 new cases are reported annually and 14,830 people die of the disease. Renal cell carcinoma, which comprises nearly 90% of all kidney cancers, is characterized by a lack of early warning signs, diverse clinical manifestations, and resistance to radiation and chemotherapy. Due to its often asymptomatic presentation, many patients have advanced disease at ...
i3 Health

Expert Guidance on New Advances in Renal Cell Carcinoma

STATEMENT OF NEED Kidney cancer accounts for approximately 4% of all cancer diagnoses in the United States (ACS, 2020). An estimated 73,750 new cases are reported annually and 14,830 people die of the disease. Renal cell carcinoma, which comprises nearly 90% of all kidney cancers, is characterized by a lack of early warning signs, diverse clinical manifestations, and resistance to radiation and chemotherapy. Due to its often asymptomatic presentation, many patients have advanced disease at ...
i3 Health

Virtual Tumor Board: Optimizing Personalized Care Plans for Patients With Metastatic Breast Cancer

STATEMENT OF NEED Breast cancer accounts for approximately 30% of cancer diagnoses among women in the United States and is the second-leading cause of cancer death in this population (ACS, 2020). Although many women benefit from regular screening as well as earlier and improved treatment, approximately 6% present with metastatic disease, and up to 30% with no initial lymph node involvement eventually develop metastatic disease (Siegel et al, 2020; Mortensen et al, 2018). Women with metastat...
i3 Health

Virtual Tumor Board: Optimizing Personalized Care Plans for Patients With Advanced Soft Tissue Sarcoma

STATEMENT OF NEED Soft tissue sarcomas are a heterogeneous group of malignancies that arise primarily from the mesodermal tissues of the extremities, trunk and retroperitoneum, and head and neck. An estimated 13,130 new cases are diagnosed in the United States annually and 5,350 people die of the disease. Surgical resection is the mainstay of treatment for localized soft tissue sarcoma, with radiation and chemotherapy commonly used as adjuncts. However, nearly 50% of patients will experienc...
i3 Health

Navigating the Recent Rheumatoid Arthritis Guidelines to Achieve Disease Remission and Reduce Patient

Roy M. Fleischmann, MD, discusses the latest evidence for the management of patients with moderate-to-severe rheumatoid arthritis who do not achieve treatment goals with initial disease-modifying anti-rheumatic drug therapy. A key treatment principle emphasized by Dr. Fleischmann is using a treat-to-target approach guided by validated tools for assessing disease activity and patient-reported outcomes. Among the treatment options, Dr. Fleischmann highlights the pharmacology of the latest approv...
Annenberg Center for Health Sciences at Eisenhower

Navigating Advancements in Diagnosis & Treatment of Axial Spondyloarthritis

More than 80% of the population has significant back pain at some point in their life, with 30% of adults in the United States stating they have chronic low back pain at any given time; 5% of whom have inflammatory back pain. Axial spondyloarthritis (axSpA) affects almost 1.5% of patients with inflammatory back pain; however, the majority of individuals suffering with back pain are not being treated by a rheumatologist, which only exacerbates the challenge to diagnose those with axSpA. Dr....
Annenberg Center for Health Sciences at Eisenhower

Research Developments in Atopic Dermatitis

Welcome to this activity focusing on new research related to atopic dermatitis presented as posters at the 2020 virtual annual meetings of the American Academy of Dermatology and the American Academy of Allergy, Asthma, and Immunology. The posters focus on new data related to the use of advanced therapies for atopic dermatitis. Beyond discussing the methods and results of each poster, the faculty, Drs. Steven Feldman and Alan Fleischer, Jr., share their views on the implication of the trial re...
Annenberg Center for Health Sciences at Eisenhower

Immune Thrombocytopenia: Evolving Treatment Paradigms and Patient-Centered Care

STATEMENT OF NEED Immune thrombocytopenia is an acquired immune-mediated disorder defined as a peripheral blood platelet count
i3 Health

Right Patient, Right Treatment, Right Time: Utilizing Early, High-Efficacy Therapies to Improve Outcomes in RRMS

Recent studies have demonstrated the benefits of early and aggressive treatment strategies in reducing disability progression and the frequency of relapses in patients with relapsing remitting multiple sclerosis (RRMS), marking a paradigm shift in the treatment of patients with RRMS. The traditional escalation approach is now often set aside in favor of the more individualized "induction" approach, which utilizes "early and aggressive" treatment with high-efficacy disease-modifying therapies (...
CME Outfitters

Beyond the Old Paradigms: Novel Approaches to the Treatment of Chronic Idiopathic Constipation

Chronic idiopathic constipation (CIC) affects 35 million adults in the United States, making it one of the most common gastrointestinal disorders. Despite the high prevalence, CIC is often underdiagnosed and undertreated, which exacts a functional, psychosocial, and economic toll on patients and their loved ones. The current treatment goal in CIC is multi-symptom relief, but only 16% of patients with CIC are on prescription therapy, and they often only obtain partial relief, with many using la...
CME Outfitters

Retooling for Modern Management of Progressive MS: An Interactive, Case-Based Activity

The approval of ocrelizumab for primary progressive multiple sclerosis (PPMS) was groundbreaking, and more recently the MS community bore witness to another major breakthrough in MS management when siponimod was approved for secondary progressive MS (SPMS). Additionally, new investigational agents such as MD1003 (high-dose biotin) and masitinib are also being evaluated for treatment of PPMS, and clinical data for both show promise for patients with SPMS. However, despite these advances, stu...
CME Outfitters

Looking Ahead: Integrating Emerging Therapies and Tools in Early-Stage Alzheimer's Disease

Alzheimer's disease (AD), a heterogeneous, neurodegenerative condition with an insidious onset and slow progression, is the leading cause of disability and morbidity as well as the sixth-leading cause of death in the United States. Diagnosing AD is often complicated due to its varied clinical symptomatology and unknown etiology, and currently only symptomatic therapies are available. Recent clinical trials investigating disease-modifying therapies (DMTs) that could slow or reverse the progr...
CME Outfitters

Hitting the Target with IL-23 Inhibitors in Psoriatic Arthiritis

Psoriatic arthritis (PsA) is a chronic, inflammatory, musculoskeletal disease with a significant impact on quality of life and functional ability. Despite the data showing the overall impact of PsA, delays in diagnosis are common, which can lead to long-term joint damage and functional disability. In this CME Outfitters Live and OnDemand activity, expert faculty will focus on assessment, treatment, and management strategies to provide patients with the best treatment aligned with evolving e...
CME Outfitters

Keeping the Beat: Screening and Management of High-Risk Patients with Non-Valvular Atrial Fibrillation

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, projected to affect 12 million Americans by 2030. However, a significant number of AF cases, particularly non-valvular atrial fibrillation (NVAF) remain undiagnosed, putting patients at risk for severe cardiovascular (CV) complications, including increased risk of stroke. It is imperative that clinicians identify the symptomatology of AF and effectively diagnose NVAF, as these complications can potentially be avoided by ...
CME Outfitters

Targeted Therapy for HER2 and HER3-Positive Breast Cancer: Navigating the Evolving Treatment Landscape

Statement of Need Breast cancer (BC) is a heterogeneous disease with human epidermal growth factor receptor 2 (HER2) overexpression and/or amplification observed in 20%-30% of cases. HER2-positive (+) BC correlates with poor clinical outcomes unless appropriately treated with targeted therapy. Despite significant therapeutic advances, many patients experience disease progression with resistance to targeted agents developing over the course of treatment. This CME Outfitters Live and OnDe...
CME Outfitters

Tumor-induced Osteomalacia (TIO): Diagnosis and Management

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic condition commonly characterized by bone pain, muscle weakness and fractures. These tumors secrete excess fibroblast growth factor 23 (FGF23) which inhibits the sodium phosphate renal co-transporters and suppresses 1α hydroxylase activity, thereby decreasing renal reabsorption and increased urinary phosphate excretion. As a result, unexplainable hypophosphatemia with a variety of musculoskeletal abnormalities are the most common sympto...
CheckRare

Neuroendocrine Tumors (NETs) Research Highlights from ENDO 2020

Although the 2020 Endocrine Society’s annual meeting (ENDO 2020) did not take place as scheduled, abstracts, including new information and data on neuroendocrine tumors (NETs) were published. This CME activity highlights the latest information about NETs from ENDO 2020 and provides expert analysis of its clinical relevance for busy members of the care team in order to help them care for patients with these rare diseases.
CheckRare

Virtual Tumor Board: Diagnosis and Management of Myelodysplastic Syndromes

STATEMENT OF NEED Myelodysplastic syndromes (MDS) are a group of heterogeneous hematopoietic disorders derived from an abnormal multipotent progenitor cell, characterized by ineffective hematopoiesis, bone marrow failure, and peripheral blood cytopenias. Survival in MDS ranges from a median of 5.3 years in lower-risk patients to as little as 0.8 years in higher-risk patients. Mortality is usually a result of infection, hemorrhage, and/or iron overload secondary to red blood cell transfusion...
i3 Health

Multiple Myeloma: Enhancing Treatment Tolerability, Adherence, and Patient-Centered Care

STATEMENT OF NEED Multiple myeloma (MM) is a B-cell neoplasm characterized by aberrant expansion of plasma cells within the bone marrow and extramedullary sites (eg, cortical bone). Approximately 32,270 new cases of MM are diagnosed in the United States annually and 12,830 people die of the disease. Although the tumor cells remain primarily within the bone marrow, they can cause a number of complications, including localized bone destruction, anemia, decreased immunity to infection, and kid...
i3 Health

Mucopolysaccharidoses (MPSs) Highlights from WORLDSymposium 2020

At WORLDSymposium 2020, new information and data were presented on Mucopolysaccharidoses (MPSs), a group of genetic lysosomal disorders. This CME activity highlights the latest information about MPSs from WORLDSymposium and provides expert analysis of its clinical relevance for busy members of the care team in order to help them care for patients with these rare diseases.
CheckRare

Gaucher Disease Highlights from WORLDSymposium 2020

At WORLDSymposium 2020, new information and data were presented on Gaucher disease, a rare lysosomal storage disorder. This CME/CNE activity highlights the latest information about Gaucher disease from WORLDSymposium and provides expert analysis of its clinical relevance for busy members of the care team in order to help them care for patients with this rare disease.
CheckRare

Fabry Disease Highlights from WORLDSymposium 2020

At WORLDSymposium 2020, new information and data were presented on Fabry disease, a rare lysosomal storage disorder. This CME/CNE activity highlights the latest information about Fabry disease from WORLDSymposium and provides expert analysis of its clinical relevance for busy members of the care team in order to help them care for patients with this rare disease.
CheckRare

@MondayNightIBD OnDemand: Addressing the Cases That Challenge Your Practice

Statement of Need Gastroenterologists are trailblazers in health care social media, and #MondayNightIBD (#MNIBD) has harnessed that energy to establish gastroenterologists as not just social media influencers but as clinical practice influencers as well. #MNIBD is not just a weekly social media conversation - it is an international platform that is moving the field forward by crowdsourcing the expertise of leading inflammatory bowel disease (IBD) experts, community clinicians, and patients ...
CME Outfitters

Improving the Quality of Care for Patients with Atopic Dermatitis: Integrating Measurement-Based Tools Into Your Clinical Practice

Statement of Need Attitudes about atopic dermatitis are evolving with the emergence of new and effective treatments. With the average dermatologist having not enjoyed caring for patients with AD for decades, there is little to no consensus in current practice about validated tools to assess and monitor the severity of the diseases and no consistent use of diagnostic or assessment tools. This lack of knowledge and education leads to confusion, poor recognition, and absence of assessment of AD ...
CME Outfitters

Navigating the New Psoriasis Guidelines: Implications for Clinical Practice

Statement of Need: The American Academy of Dermatology (AAD) and the National Psoriasis Foundation (NPF) have recently released new joint guidelines that outline best practices for the management of psoriasis (PsO) with biologics, the need for awareness and attention to comorbidities, and guidelines for pediatric PsO treatment. Clinicians must ensure that they are aware of these guidelines and of strategies to incorporate them into clinical practice, including the integration of biologic ther...
CME Outfitters

At-Risk Patients Hidden in Plain Sight: Real-World Strategies for Screening and Treating Hepatitis B Virus

Statement of Need Chronic hepatitis B virus (HBV) remains a global epidemic, resulting in significant morbidity and mortality. In 2015, there were 257 million people worldwide infected with HBV. In 2016, only 10.5% were diagnosed, with only 16.7% receiving treatment, and without intervention, there are 19 million deaths anticipated by the end of 2020. These numbers are startling as they exist despite the availability of effective treatment, and this is in part due to lack of clinician knowl...
CME Outfitters

A Deeper Dive into NASH Diagnosis and Treatment: An Augmented Reality Experience

Statement of Need Obesity and diabetes are on the rise, leading to an increased prevalence of non-alcoholic fatty liver disease (NAFLD), which in some cases may progress to non-alcoholic steatohepatitis (NASH). NAFLD effects approximately 30% of the U.S. population, with NASH effecting about 5%. NASH comes with a significant risk of progression to advanced liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Disease models project that the number of individuals with end-stage live...
CME Outfitters

What the Future Holds for NASH: An Augmented Reality Look into Disease Stating and Targeted Therapies

Statement of Need Given the rising prevalence of non-alcoholic fatty liver disease (NAFLD) and the societal and economic burden of its aggressive subtype, non-alcoholic steatohepatitis (NASH), it is important that hepatologists and gastroenterologists are equipped with the latest tools to diagnose NASH. While there are currently no approved therapies for the treatment of NASH, several targeted therapies are being investigated in clinical trials, with high probability of being approved in the ...
CME Outfitters

Nursing Management of Myelofibrosis: Controlling Symptoms and Optimizing Patient Quality of Life

STATEMENT OF NEED Myeloproliferative neoplasms are a heterogeneous group of hematopoietic disorders that includes myelofibrosis, polycythemia vera (PV), and essential thrombocythemia (ET). These malignancies affect approximately 13,000, 134,000, and 148,000 individuals in the United States, respectively. As symptoms do not typically manifest in early stages, patients with MPNs often present with advanced disease. The presence of comorbidities precludes most from potentially curative allogen...
i3 Health

Addressing the Burden of Psoriatic Arthritis: Moving Beyond the Joint

Philip J. Mease, MD, and Alexis R. Ogdie-Beatty, MD, review the pathogenesis and a wide spectrum of clinical features, manifestations, and comorbidities of psoriatic arthritis; talk about classification criteria for PsA and different patient-reported and provider-assessed outcome measures; and discuss treatment recommendations and strategies, as well as various types of current and emerging therapies. Finally, they highlight some of the key issues and challenges of the management of PsA throug...
Annenberg Center for Health Sciences at Eisenhower

Optimizing Personalized Care Plans for Patients With Advanced Non-Small Cell Lung Cancer

STATEMENT OF NEED An estimated 228,150 new cases of lung cancer are reported in the United States annually, and 142,670 people die of the disease. The major subtypes are non-­small cell (84%) and small cell (13%). Most patients with lung cancer are diagnosed at a locally advanced or metastatic stage, making systemic therapy the cornerstone of management. Although 70% of patients receiving first-line classical doublet chemotherapy demonstrate clinical benefit, most develop progressive disea...
i3 Health

New Thinking, New Strategies in Advanced Urothelial Carcinoma

STATEMENT OF NEED Bladder cancer is the sixth most common malignancy among adults in the United States. Approximately 80,470 new cases are diagnosed annually and 17,670 people die of the disease. More than 90% of patients with bladder cancer have the urothelial carcinoma subtype, which has a high rate of recurrence whether it is low or high grade. Approximately half of all bladder cancers are diagnosed in situ, for which the 5-year relative survival rate is 95%. For tumors diagnosed as a lo...
i3 Health

Enhancing Treatment Experiences in Castration-Resistant Prostate Cancer: The Nurse's View

STATEMENT OF NEED Prostate cancer is the most common tumor type affecting men in the United States, with an estimated 174,650 new cases reported each year. Typically, androgen deprivation therapy is administered for progressive disease. However, castration resistance or unresponsiveness to androgen deprivation therapy or to antiandrogens frequently develops over time. The transition from castration-sensitive to castration-resistant disease has yet to be understood and represents a significa...
i3 Health

TTR Amyloidosis

By learning more about the pathophysiology of rare diseases like TTR Amyloidosis, members of the care team who may encounter these patients on their diagnostic journeys can have a profound impact on their ultimate outcomes.
CheckRare

Clinical Insights on Recent Advances in Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is a leading, fatal, autosomal recessive disorder that affects approximately one in 10,000 live births. Nusinersen was approved as the first targeted therapy for SMA, and since its groundbreaking approval data has been published that demonstrates its efficacy for both infantile- and later-onset SMA populations. Additionally, recent guidelines were published that provide evidence-based recommendations for the diagnosis and management of SMA. However, despite the...
CME Outfitters

Food Allergy: From Primary Prevention to Treatment and Intervention Online

This online offering includes 19 videos of lectures and panel discussions on the diagnosis and management, specific syndromes, treatment, and research and prevention of food allergy. The videos were recorded at a live course that took place at a live AAAAI course held in early September, 2019. The intent of the videos is to allow learners to increase their knowledge related to the diagnosis and management of food allergic patients. It highlights the latest evidence related to food allergie...
American Academy of Allergy, Asthma & Immunology

Conversations from the World of Allergy: Podcast Episodes for Credit

This podcast features interviews on a wide variety of allergy/immunology topics. It is our hope that the conversations provide evidence-based information that is useful to clinicians, researchers and patients, alike. Some episodes are available for CME credit. All podcast episodes are available at https://www.aaaai.org/professional-education-and-training/podcasts
American Academy of Allergy, Asthma & Immunology

Virtual Patient: Asthma in the Older Adult

This patient simulation requires an evaluation and creation of a treatment plan for an older adult (>65 years old) with asthma. The case involves identification of differences and similarities between asthma and COPD in older adults and consideration of medications and co-morbid conditions that may complicate the management of asthma in this population. A summary of the literature supporting best practices in asthma care in the older adult will be provided.
American Academy of Allergy, Asthma & Immunology

BMTCN® Exam Review - Miami

This program is designed for BMT oncology nurses seeking a review in preparation for the ONCC® Blood & Marrow Transplant Certified Nurse (BMTCN®) Exam. The review will focus on the following categories from the 2016 test content outline: indications for transplantation, types of transplants and stem-cell sources, pretransplant care, preparative regimens, stem-cell infusion, graft-versus host disease, post-transplant care, survivorship and professional practice. This is not an introductory co...
MED-ED

Vaccination Needs in Older Populations

Older adults are especially susceptible to vaccine-preventable illnesses and vaccine recommendations have been updated to reflect recent advances that impact older people. Clinicians who care for, or interact with, older adults can be advocates for vaccination and should be familiar with the most recent changes to vaccine schedules. Additionally, it’s important that clinicians understand the impact of COVID-19 on vaccinations among older vulnerable patients, and how to reduce their risk for ...
American Academy of CME

When Is Switching ART Necessary?

In this CME Outfitters BriefCase, faculty will highlight a patient case that focuses on seizing opportunities to optimize and simplify treatment for patients with human immunodeficiency virus (HIV) while maintaining virologic suppression, as well as best practices for engaging patients in shared decision-making so that patient preference is always considered. At the end of this CE activity, participants should be able to: -Determine appropriate strategies for treatment switching. The fo...
CME Outfitters

Weighing the Evidence: A Pharmacy Approach to Stroke Prevention in Obese Patients with Non-Valvular Atrial Fibrillation

In this CME Outfitters virtual symposium, expert faculty will review key aspects of the prescribing information, guidelines, and recently published safety and efficacy data for DOACs and warfarin in order to enable pharmacists and other clinicians to support evidence-based therapeutic treatment decisions in obese patients with NVAF. At the end of this CE activity, participants should be able to: -Assess existing guidelines and U.S. prescribing information for use of DOACs and warfarin to p...
CME Outfitters

@MondayNightIBD: identifying the Factors that Impact Success in Your Practice

In this webcast, CME Outfitters and @MondayNightIBD come together to bring you a panel of experts who will tailor a series of patient cases. These cases will focus on the application of cutting-edge data for novel therapies, identifying appropriate treatment strategies for special populations such as young patients and racial/ethnic minorities, and developing patient communication strategies, with the aim of achieving optimal patient outcomes. At the end of this CE activity, participants sh...
CME Outfitters

The Role of Immune Checkpoint Inhibitors in the Treatment of Genitourinary Cancers: An Interprofessional Perspective on Guideline Updates

The landscape of genitourinary cancer therapy is evolving. As treatment options expand and are integrated into treatment regimens, and guidelines are updated to reflect these advances, there is an ongoing need for the members of the care team to engage in continuing education in this area. Additionally, as the pandemic continues, it’s important that clinicians recognize and apply strategies for reducing the risk of COVID-19 infection in vulnerable patients. -Review key updated guideline r...
American Academy of CME

Research Developments in Rheumatoid Arthritis

The past decade has provided numerous advances in the treatment of rheumatoid arthritis. As will be discussed, recent evidence of 2 medications from different classes provide reassurance as to their long-term safety and efficacy. Of key importance is that these treatment advances provide a real opportunity to achieve disease remission using a treat-to-target approach. The benefits of achieving long-term disease remission vs low disease activity are presented. Join Dr. Roy Fleischmann as he dis...
Annenberg Center for Health Sciences at Eisenhower

Nursing Perspectives in the Management of Multiple Myeloma

The landscape of multiple myeloma therapy is evolving. There is an ongoing need for clinician education as treatment options expand and are integrated into treatment regimens, and guidelines are updated to reflect these advances. Nursing considerations are different with newer agents compared to standard chemotherapy. Additionally, it’s important that clinicians understand the impact of COVID-19 and how to reduce the risk of infection in vulnerable patients. Upon completion of the educati...
American Academy of CME

Pull the Levers That You Can: Managing HIV in an Aging Population

In this CME Outfitters BriefCase, expert faculty will present a patient case focusing on the impact of comorbidities and how to individualize treatment regimens for aging patients with HIV, based on their specific needs and comorbidities. At the end of this CE activity, participants should be able to: -Individualize treatment regimens for aging patients with HIV, based on their specific needs and comorbidities. The following learning objectives pertain only to those requesting CNE or CP...
CME Outfitters

Choosing ART: What Does the Evidence Say?

This CME Outfitters BriefCase focuses on incorporating the latest evidence-based and guideline-directed treatment strategies for a patient who has been newly diagnosed with HIV. At the end of this CE activity, participants should be able to: -Incorporate the latest evidence-based and guideline-directed treatment strategies in the management of patients newly diagnosed with HIV. The following learning objectives pertain only to those requesting CNE or CPE credit: -Assess the latest evid...
CME Outfitters

Implementing a Shingles Protocol in Specialty Practices

This CMEOCast podcast focuses on best practices to increase vaccine uptake and completion in vaccine-eligible patients and those at risk who present to specialty settings. The podcast will address ideal strategies to store and administer RZV, counseling patients on the extensive burden associated with shingles, and the benefits and potential risks of vaccination. At the end of this CE activity, participants should be able to: -Develop best practices to implement a shingles protocol in spec...
CME Outfitters

Implementing a Shingles Protocol in Primary Care Settings

The first episode of this CMEOCast podcast series focuses on reinforcing the importance of vaccination against shingles, improving vaccination uptake in ethnic minorities and at-risk patients, and developing best practices to implement a shingles protocol in primary care settings. At the end of this CE activity, participants should be able to: -Develop best practices to implement a shingles protocol in primary care settings. The following learning objectives pertain only to those reques...
CME Outfitters

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