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Fabry Disease Research Highlights
This 30-minute CME-accredited program highlights the latest clinical research about Fabry disease, a rare X-linked lysosomal disorder that results in the cellular buildup of globotriaosylceramide. Characteristic features of Fabry disease include acroparesthesias, angiokeratomas, hypohidrosis, corneal opacity, gastrointestinal problems, tinnitus, and hearing loss. Fabry disease also involves potentially life-threatening complications such as progressive kidney damage, heart attack, and stroke.
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Leveraging BCMA-Directed Therapies for Improved Patient Outcomes in Relapsed/Refractory Multiple Myeloma
STATEMENT OF NEED
Multiple myeloma is a disease that remains incurable for most patients, many of whom become refractory to the majority of available treatments (Kumar et al, 2022). It is estimated that 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Agents targeting B-cell maturation antigen (BCMA), including antibody-drug conjugates (ADCs), chimeric antigen receptor (CAR) T-cell therapies, and bis... |
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Warm Autoimmune Hemolytic Anemia (wAIHA)
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis.
Current recommendations for managing people with wAIHA are largely based on case series and retrospective studies involving off-label medications. Also, while there are currently no medications specifically approved to treat wAIHA, data are emerging on new... |
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Hitting the Target in HER2-Positive Metastatic Colorectal Cancer
STATEMENT OF NEED
An estimated 153,020 new cases of colorectal cancer (CRC) are diagnosed annually, and 52,550 people die of the disease (Siegel et al, 2023). Approximately 22% of patients present with metastatic disease, which is associated with a dismal 5-year survival rate of 15% (SEER, 2022). Targeting biomarkers is a key strategy for expanding therapeutic options and improving outcomes in metastatic CRC. Human epidermal growth factor receptor 2 (HER2) amplification status and treatment... |
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Building and Maintaining a Multidisciplinary Team for Lysosomal Disorders
This CME/CE activity with Drs. Ozlem Goker-Aplan and Walla Al-Hertani describes the importance of a multidisciplinary team approach to managing lysosomal diseases, as well as some of the challenges involved in creating and maintaining that team.
At the end of this activity, participants should be able to:
- Describe the need for a team approach to care
- Describe best practices to build a multidisciplinary team for a new patient
- Describe best practices to maintain a multidisciplinary... |
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Expert Guidance on Current Standards and New Directions in Newly Diagnosed Multiple Myeloma
STATEMENT OF NEED
An estimated 35,730 new cases of multiple myeloma are diagnosed in the United States annually, and 12,590 people die of the disease (Siegel et al, 2023). Characterized by clonal proliferation of malignant plasma cells in the bone marrow, multiple myeloma is associated with anemia, renal insufficiency, bone destruction, and hypercalcemia, all of which significantly impact patients’ quality of life. The development of novel therapies and combinations in recent years, inclu... |
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Myasthenia Gravis Research Highlights: AAN 2023
This 30-minute CME program highlights the latest clinical research about myasthenia gravis, a rare, autoimmune disease that targets the neuromuscular junction.
Treatment of myasthenia gravis is highly individualized and depends greatly on the myasthenia gravis subtype of each patient as well as each patient’s comorbidities. There are currently four drugs approved by the FDA, eculizumab, efgartigimod, ravulizumab, and rozanolixizumab. There are also treatments in development. Clinical tria... |
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Leveraging the Growing Arsenal of Adjuvant Therapies for Early-Stage NSCLC
In this activity, Dr. Helena A. Yu, Associate Attending Physician at Memorial Sloan Kettering Cancer Center, will provide insights into strategies for leveraging the growing arsenal of adjuvant therapies for early-stage non"small cell lung cancer (NSCLC), including treatment selection and adverse event management. Start the activity now!
STATEMENT OF NEED
Lung cancer is the second most commonly diagnosed cancer and the leading cause of death for men and women worldwide. In the Unite... |
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Pathology and Oncology Expert Perspectives in the Management of Triple-Negative Breast Cancer: Case Explorations and Answers to FAQs
STATEMENT OF NEED
Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for approximately 10% to 15% of breast cancer diagnoses and is characterized by the absence of estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2 (HER2). TNBC is more common in Black women and in women under the age of 40 (ACS, 2023). Compared with other subtypes of invasive breast cancer, TNBC has high rates of metastasis and a poor prognosis. Due to the lack ... |
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Virtual Tumor Board: Multidisciplinary Management of Advanced Soft Tissue Sarcoma
STATEMENT OF NEED
Sarcomas, which represent 1% to 2% of adult cancers, are a rare, heterogeneous group of neoplasms originating in the connective tissue. Soft tissue sarcomas, which begin in the muscle, tendons, fat, lymph, blood vessels, and nerves, encompass more than 80 histological subtypes. Approximately 25% of patients develop metastatic disease after curative-intent surgery, and for these patients, treatment options are limited and prognosis is very poor. In recent decades, the ident... |
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Putting the Freeze on Cold Agglutinin Disease
STATEMENT OF NEED
Cold agglutinin disease (CAD) is a rare subtype of autoimmune hemolytic anemia (AIHA) in which antibodies cause hemolysis at cold temperatures, generally between 37º to 39º Fahrenheit. Approximately 1 in a million people are affected by CAD annually, with onset usually occurring between the ages of 40 and 80 years. Individuals commonly experience fatigue, dizziness, palpitations, and shortness of breath caused by the anemia; jaundice caused by degradation of hemoglobin i... |
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Managing Patients with Rheumatic Disorders in Primary Care
Rheumatic disorders are prevalent, yet their diagnosis and treatment in affected patients are frequently challenging, contributing to a considerable disease burden. Ensuring timely intervention is critical to slow disease progression and improve patient outcomes. However, various educational gaps impede primary care clinicians from effectively achieving these goals. This 0.75-hour text-based activity features 3 modules comprised of 12 questions encountered in the primary care management of pat... |
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Acromegaly Research Highlights: ENDO 2023
This 30-minute CME-accredited program highlights the latest clinical research about acromegaly, a rare endocrine disorder. Common symptoms include subtle skeletal overgrowth; soft tissue swelling (tongue, heart, kidney, colon, and vocal cords); unusually prominent forehead and heavy brow ridge; protruding lower jaw; overbite; skin thickening; increased shoe and ring size; hypertension; increased perspiration; headaches; paresthesia; and sexual dysfunction.
There are several orphan drugs app... |
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New Guidance to Diagnose and Treat Tumor-induced Osteomalacia (TIO)
This 30-minute CME-accredited program, hosted by Aliya Khan, MD, Clinical Professor of Medicine at McMaster University, highlights the best practices to diagnose and treat tumor induced osteomalacia (TIO) based on the recently published global guidance document in the Journal of Internal Medicine.
This activity has been designed to meet the educational needs of physicians specializing in neurology, orthopedics, internal medicine/general practice, rheumatology, endocrinology, pain management... |
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Myasthenia Gravis and the Complement System
This 45-minute CME-accredited program, hosted by James F Howard Jr, MD, Professor of Neurology, Medicine & Allied Health at The University of North Carolina at Chapel Hill, highlights the connection between the complement system and myasthenia gravis in regards to the pathophysiology and treatment of this rare disease.
After participating in the activity, learners should be better able to:
- Review the pathophysiology of MG.
- Describe the role of the complement system in MG.
- Descr... |
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Exploring New Treatment Advances for Acid Sphingomyelinase Deficiency in Adults
STATEMENT OF NEED
Acid sphingomyelinase deficiency (ASMD) is a rare, hereditary lysosomal storage disease with multisystemic manifestations, including splenomegaly, hepatomegaly, interstitial lung disease, dyslipidemia, bone marrow and lymph node involvement, and sometimes neurological and peripheral nerve involvement. While the most severe form of ASMD, infantile neurovisceral ASMD, results in death in early childhood, chronic forms of ASMD have more prolonged survival but are associated w... |
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Current Standards and New Directions in the Treatment of Acquired Thrombotic Thrombocytopenic Purpura
STATEMENT OF NEED
Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare, life-threatening thrombotic microangiopathy with a rapid onset and progression and a mortality rate of 10% to 20% with prompt treatment. Onset of aTTP is characterized by severe thrombocytopenia, microangiopathic hemolytic anemia, and a constellation of associated symptoms including hemorrhage, neurologic and renal manifestations, cardiac abnormalities, and mesenteric ischemia (Joly et al, 2017). Survivors of f... |
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Recurrent and Metastatic HNSCC: New Insights and Real-World Evidence for Improved Patient Outcomes
STATEMENT OF NEED
Head and neck cancers represent a heterogeneous group of tumors that originate in the lip/oral cavity, hypopharynx, oropharynx, nasopharynx, and larynx. An estimated 66,470 new cases are diagnosed in the United States annually, and 15,050 people die of the disease (Siegel et al, 2022). Approximately 90% of cases are classified as head and neck squamous cell carcinoma (HNSCC). Treatment of HNSCC is complicated by numerous factors, including differing therapeutic strategies ... |
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Exploring Novel Treatments for Rett Syndrome
STATEMENT OF NEED
Rett syndrome is a rare, debilitating neurodevelopmental disorder almost always associated with a spontaneous mutation in the methyl-CpG-binding protein 2 (MECP2) gene on the X-chromosome. Affected individuals experience loss of purposeful hand skills, abnormalities in gait, loss of spoken language, and stereotypic hand movements, with more severe manifestations including seizures, autistic features, autonomic nervous system dysfunction, breathing abnormalities, sleep dist... |
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The Expanding Role of Fluid Biomarkers in the Diagnosis and Management of Patients With Alzheimer Disease
Target Audience
This educational activity is directed toward geriatric psychiatrists, geriatricians, psychiatrists, psychologists, nurse practitioners, physician assistants, and other health care professionals involved in the management of patients with, or at risk of developing, Alzheimer disease.
Program Overview
A variety of proteins related to various aspects of Alzheimer disease (AD) pathophysiology have been suggested as biomarkers for the condition. Cerebrospinal fluid biomarkers r... |
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Clinical Evidence for COVID PrEP, With Drs. Leonard Calabrese and Myron Cohen
In this podcast, expert clinicians will review recent developments involving monoclonal antibody therapies for COVID-19 and discuss ongoing studies on pre-exposure prophylaxis for immunocompromised patients. |
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Pathways to Developing Personalized Treatment Regimens for Patients with Advanced Melanoma
No two patients with advanced melanoma are the same and tailoring treatment is vital. Immerse yourself in this interactive “choose your path” digital algorithm with expert perspectives to assist with the application of new guidelines and treatment options to optimize therapy.
Do you have questions about treating patients with advanced melanoma? Do you wonder…
• When to use immune checkpoint inhibitors (ICIs), and in which combinations?
• How to select among the growing number o... |
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Introduction to Adult Echocardiography
Introduction to Adult Echocardiography Live Training & CME Course is a five (5) day comprehensive echocardiography course in St. Petersburg, FL that is taught by leading echocardiography experts and is designed to provide a strong foundation to perform and/or interpret adult cardiac ultrasound examinations. All topics of discussion are based on ASE, ACEP, and WINFOCUS ultrasound practice guidelines.
The structure of the course is a combination of live lectures, scanning demonstrations, ... |
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Best of Lipid Forum®: Examining the Role of Lp(a) as a Risk Factor in Atherosclerotic Cardiovascular Disease
Lipoprotein(a) [Lp(a)] is a low-density lipoprotein particle that is associated with poor cardiovascular prognosis due to its pro-atherogenic, pro-thrombotic, pro-inflammatory and pro-oxidative properties. Unfortunately, traditional lipid-lowering therapy does not provide sufficient Lp(a) reduction. High levels of Lp(a) are an independent and causal risk factor for atherosclerotic cardiovascular disease (ASCVD) through mechanisms associated with increased atherogenesis, inflammation, and throm... |
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Best of Lipid Forum®: Examining the Role of Lp(a) as a Risk Factor in Atherosclerotic Cardiovascular Disease
Lipoprotein(a) [Lp(a)] is a low-density lipoprotein particle that is associated with poor cardiovascular prognosis due to its pro-atherogenic, pro-thrombotic, pro-inflammatory and pro-oxidative properties. Unfortunately, traditional lipid-lowering therapy does not provide sufficient Lp(a) reduction. High levels of Lp(a) are an independent and causal risk factor for atherosclerotic cardiovascular diseases (ASCVD) through mechanisms associated with increased atherogenesis, inflammation, and thro... |
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Cleveland Clinic State of the Art Echocardiography (Online & DVD-ROM)
Cleveland Clinic’s State of the Art Echocardiography highlights practical issues in echocardiography, featuring insight and real world cardiovascular clinical practice cases from nearly 30 internationally renowned experts. This activity provides guidance for optimal utilization of echocardiography in managing valvular heart disease, heart failure, device therapies, cardiomyopathies and endocarditis. Special sessions will be dedicated to structural heart interventions, adult congenital cardi... |
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Office Practice of Primary Care Medicine 2024 - LIVE STREAMING
The Comprehensive 2024 Update on Office-Based Primary Care Medicine
Taught Live Online by Harvard Medical School's Leading Clinical Faculty
Office Practice of Primary Care Medicine will be held online this year, using live streaming, electronic Q&A, and other remote learning technologies.
OVERVIEW
Office Practice of Primary Care Medicine provides comprehensive reviews of the most important recent advances impacting primary care medicine and guidance to assimilate these changes... |
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Introduction to Culturally and Linguistically Appropriate Services (CLAS) and Minority Health Disparities
This course helps you incorporate into practice the National Culturally and Linguistically Appropriate Services (CLAS) standards of the USDHHS Office of Minority Health.
Outcome Objectives:
As a result of completing this activity, the participant will be better able to:
- Describe the National Culturally and Linguistically Appropriate Services (CLAS) standards of the USDHHS Office of Minority Health and how they impact the ethical responsibilities of medical service providers.
- Defi... |
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Skin Cancer Education for Primary Care
This comprehensive course on skin cancer will help you improve your ability to diagnose and manage skin lesions, the most common of all cancers.
Outcome Objectives:
As a result of completing this activity, the participant will be better able to:
- Understand the biology of ultraviolet radiation and methods to protect the skin.
- Demonstrate increased proficiency in the management of potentially malignant skin lesions.
- Make early diagnoses of skin cancers, particularly melanoma.... |
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Parkinson's Disease Update
The Parkinson’s Disease Update is a half-day course designed to support primary care physicians, general neurologists, and advanced practitioners in the care of these patients. Our focus on Parkinson's Disease (PD) management will cover genetics in PD; standard and novel treatments of PD to include medical, surgical, and alternative medications; as well as the timing of referral to a movement disorder specialist or for surgical treatment. The course will conclude with talks on palliativ... |
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Operation Game- A Patient’s Journey Through HeFH: Diagnosis and Management
Target Audience
This activity has been designed to address the educational needs of cardiologists, cardiology nurses, lipid specialists, and primary care clinicians, including internists, pharmacists, nurses, nurse practitioners, PAs, and dietitians. It may also benefit other healthcare providers who manage patients with hypercholesterolemia.
Program Overview
Nonstatins are an essential therapy for lowering low-density lipoprotein cholesterol (LDL-C) levels in high-risk patients, such as ... |
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Pulmonary and Critical Care Medicine 2024 - LIVE STREAMING
Comprehensive Updates for State-of-the-Art Evaluation, Diagnosis, and Treatment
This comprehensive live streaming online course, which is among the highest-rated Harvard Medical School CME courses, provides education and updates to optimize your care of patients with:
• Sepsis
• ARDS
• Sarcoidosis
• IPF
• Bronchiectasis
• Cystic fibrosis
• Lung nodules
• Lung cancer
• GERD
• Pleural disease
• Pneumonia
• Tuberculosis
• Thromboembolism
• Chronic cou... |
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Acromegaly: Improving Timely Diagnosis, Assessment, and Treatment
Acromegaly, caused by excessive growth hormone production from the anterior pituitary gland, results in disproportionate growth of body tissues and other metabolic dysfunctions. With causes divided into primary GH excess, ectopic or iatrogenic GH excess, and excess growth hormone-releasing hormone (GHRH), adult patients have the characteristic facial features of a large lower jaw, a prominent forehead, and large hands and feet. These features occur after the growth plates are fused, distinguis... |
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Advancing the Care of Patients Living with EGPA Through Multidisciplinary, Patient-Focused Care
Target Audience
This educational activity is intended for rheumatologists, allergists, immunologists, pulmonologists, and specialty advance practice clinicians who care for patients with EGPA.
Program Overview
The comprehensive program provides up-to-date information regarding EGPA"its recognition, diagnosis, and treatment"and incorporates the patient perspective to raise awareness of patients’ needs, heighten urgency, and, ultimately, educate on the disease. The program will ... |
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Right Treatment, Right Patient: Evidence-Based Approaches to the Treatment of Moderate-to-Severe Atopic Dermatitis Snippet 1: Currently Available Injectable Biologic Therapies for Moderate-to-Severe Atopic Dermatitis (AD)
Target Audience
This activity is designed to meet the educational needs of dermatology and allergy physicians, nurse practitioners, PAs, and nurses who care for patients with moderate-to-severe atopic dermatitis.
Program Overview
This activity features a case presentation, a brief overview of currently available injectable biologic therapies, and insights from an expert faculty.
Learning Objectives
After completing this activity, the participant should be better able to::
Identify ... |
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Infectious Diseases in Adults 2024 - LIVE STREAMING
State-of-the-art approaches to prevention, diagnosis, and treatment of infectious diseases
This comprehensive Harvard Medical School CME program"one of the highest-rated HMS CME courses"ensures attendees are current with state-of-the-art approaches to prevention, detection, diagnosis, and treatment of infectious diseases. Updates, best practices and new guidelines are presented by nationally recognized ID experts and master clinicians. Education is practical and results driven:
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Ace the Case: A 47-Year-Old Man With Oral Corticosteroid-Dependent Asthma
This educational activity will utilize a case study to discuss a 47-year-old man with oral corticosteroid"dependent asthma. |
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Ace the Case: A 34-Year-Old Woman With Painful Swallowing
This educational activity will utilize a case study to discuss a 34-year-old woman with painful swallowing that has been progressively worsening for the past few days and is associated with anorexia, nausea, and epigastric abdominal pain. |
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Ace the Case: A 62-Year-Old Woman With Unintentional Weight Loss of 20 Pounds
This educational activity will utilize a case study to discuss a 62-year-old woman with a 20-pound unintentional weight loss and recurrent emesis over the past 3 months. |
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Real-World Perspectives in Managing CLL Treatment
Management options for chronic lymphocytic leukemia (CLL) have expanded in recent years. The emergence of new immunotherapeutic and targeted agents for both the first-line and relapsed/refractory settings"though of course beneficial for CLL patients"represents a challenge to clinicians, who must navigate the indicated uses, mechanisms of action, and toxicity profiles of these new agents. In determining optimal treatment plans, clinicians are also confronted with significant advances ... |
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May 16-18, 2024 Update CME Internal Medicine and Primary Care Conference
Eminent speakers from The University of Chicago, Northwestern University, The University of Illinois Chicago, and Rush University will provide comprehensive updates on the latest clinical guidelines.
Target Audience: Internal Medicine, Primary Care, Family Medicine, and Hospitalist Medicine Physicians, Nurse Practitioners, and Physician Assistants
Earn 25 CME Credits
This activity has been approved for AMA PRA Category 1 Credit™️.
This activity has been approved for AAFP Prescribe... |
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Introduction to Musculoskeletal Ultrasound - Blended
The Blended Introduction to Musculoskeletal Ultrasound Training Course provides participants a comprehensive introduction to upper and lower extremity musculoskeletal ultrasound for diagnostic applications and ultrasound guided injection/aspiration techniques. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading musculoskeletal ultrasound experts, the online course incorporates comprehensive lectu... |
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Introduction to Musculoskeletal Ultrasound with Interventional Human Cadaver Lab - Blended
The Blended Introduction to Musculoskeletal Ultrasound with Interventional Cadaver Lab Training Course provides participants a comprehensive introduction to upper and lower extremity musculoskeletal ultrasound for diagnostic applications and ultrasound guided injection/aspiration techniques. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading musculoskeletal ultrasound experts, the online course ... |
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Peripheral Nerve Ultrasound - Blended
The Blended Peripheral Nerve Ultrasound Course is designed to provide a comprehensive approach to the use of ultrasound for the assessment and treatment of peripheral nerves. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading peripheral nerve and musculoskeletal ultrasound experts, the online course incorporates a comprehensive review of the sonographic appearance and recognition of upper and lo... |
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Peripheral Nerve Ultrasound with Interventional Human Cadaver Lab - Blended
The Blended Peripheral Nerve Ultrasound with Interventional Cadaver Lab Training Course is designed to provide a comprehensive approach to the use of ultrasound for the assessment and treatment of peripheral nerves. The Blended Education format provides flexibility while providing time and cost savings.
Begin with the self-paced online course: Taught by leading peripheral nerve and musculoskeletal ultrasound experts, the online course incorporates a comprehensive review of the sonographic a... |
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InformED: UC Davis Emergency Medicine Conference
This conference is catered to practitioners who provide care in urgent and emergent settings, including physicians, physician assistants, nurse practitioners, nurses, and pharmacists. Health care is changing rapidly where urgent and emergent conditions require rapid, accurate diagnosis and treatment decisions. Nationally recognized leaders in Emergency Medicine will deliver the course that provides opportunities for attendees to learn about current and progressive trends in the practice of eme... |
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INFORM: Information Needed for Optimal Regulation of Mycophenolate- A REMS Activity
Target Audience
The target audience for this initiative includes obstetricians, gynecologists, primary care physicians, physician assistants, nurse practitioners, pharmacists, and care team members involved in the treatment of women across their reproductive lifespan who may have been prescribed mycophenolate products.
Program Overview
Clinicians who work with women of childbearing age who are, or will be, taking mycophenolate must ensure that their patients receive appropriate counseling... |
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9th Annual Clinical Issues in Primary Care Conference
Presented by Continuing Education Company for over 30 years, our Primary Care CME Conference Series is designed to update primary care clinicians in rapidly changing therapeutic areas. The emphasis is on practical and useful information for clinical practice. Join us in May 2024 for our 9th Annual Clinical Issues in Primary Care Conference at the Fairmont Orchid, Hawaii Resort on the Big Island
Program Objectives
As a result of this conference, participants will be able to:
Assess and p... |
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Anesthesiology Update 2024 - LIVE STREAMING or IN PERSON
The Comprehensive 2024 Anesthesiology Update
Cardiac, Regional, Office-Based, Thoracic, Obstetric, Neuro, and Pediatric
Anesthesiology Update will be held on May 6-10, 2024. You have the option to attend either online as the course is live streamed or in person in Boston, MA.
In the past year, there have been a number of very significant clinical changes that affect the practice of anesthesiology. This comprehensive CME program provides a special and timely opportunity for anesthesiolo... |
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Duchenne Muscular Dystrophy: Recognizing Its Earliest Signs in Infancy and Care Transition into Adulthood
Target Audience
The intended audience for this activity are neurologists, neuromuscular specialists, pediatric neurologists, genetic counselors, and pediatricians.
Program Overview
Join a panel of expert clinicians to identify the subtle and very early signs of DMD that may be detected before functional symptoms are noticed and that can help earlier diagnoses and appropriate interventions. Panelists will review the importance of matching mutations to therapeutic decisions, discuss emergin... |
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