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NeuroRehabilitation 2025 - LIVE STREAMING
Comprehensive Neurorehabilitation Update
Cutting-edge strategies, updates, and best practices for state-of-the-art rehabilitation
In this course, which is among the highest-rated Harvard Medical School CME courses, many of the country’s most experienced and committed neurorehabilitation experts will present cutting-edge clinical interventions, the latest findings, practical education, and hands-on methods to further your expertise in guiding your patients with stroke, SCI, TBI, and fun... |
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Highlights from PAS: Rare Disorders - Don't Miss a Treatable Disease
Target Audience
This activity is designed to meet the educational needs of neonatologists, pediatricians, geneticists, family practice, registered nurses, nurse practitioners, physician assistants, genetic counselors, and other HCPs who wish to improve their knowledge and competence in identifying and managing patients with treatable rare disorders through NBS as well as other measures.
Program Overview
This activity will feature clinical cases where newborn screening (NBS) identified a t... |
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Veterinary Compounding Essentials
June 6th -7th, 2025
Veterinary Compounding Essentials is a 15-hour (1.5 CEUs) accredited course for pharmacists, technicians, and marketers. This hands-on program covers key skills for growing a veterinary compounding practice, including calculations, compounding techniques, safety protocols, USP guidelines, and marketing strategies. Participants will learn how to choose appropriate flavors, understand animal-specific regulations, assign BUDs, use PPE, and prepare common formulations like t... |
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Introduction to Carotid Duplex/Color Flow Ultrasound - Blended Course
The Introduction to Carotid Duplex/Color Flow Imaging Blended Course will give you a strong foundation to begin performing and/or interpreting Carotid Ultrasound Examinations. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading vascular ultrasound experts, the comprehensive online course covers cerebrovascular anatomy& physiology, Doppler principles, scan techniques, and interpret... |
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Introduction to Adult Echocardiography - Blended Course
The Introduction to Adult Echocardiography Blended Course will give you a strong foundation to begin performing and/or interpreting comprehensive adult cardiac examinations. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading echocardiography experts, the comprehensive online course covers cardiac anatomy & physiology, 2D & M-mode scan techniques cardiac Doppler principles, ev... |
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Introduction to Peripheral Vascular Ultrasound - Blended Course
The Introduction to Peripheral Vascular Duplex/Color Flow Imaging Blended Course will give you a strong foundation to begin performing and/or interpreting Peripheral Vascular Duplex/Color Flow Imaging and Indirect PV Ultrasound Examinations. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading vascular ultrasound experts, the comprehensive online course covers peripheral arterial and v... |
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Introduction to Transcranial Doppler Ultrasound " Blended Course
The Introduction to Transcranial Doppler Ultrasound Blended Course will give you a strong foundation to begin performing and/or interpreting transcranial Doppler examinations. The Blended Education format provides flexibility while saving you time and minimizing travel costs.
Begin with the self-paced online course: Taught by leading vascular ultrasound experts, the online course provides a comprehensive review of neuro-anatomy, normal and abnormal Doppler waveform characteristics, and scan... |
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POCUS for Family Medicine - Live Course
The POCUS for Family Medicine Live Training Course provides participants a strong foundation to perform and/or interpret all of the core ultrasound applications in an urban and rural family medicine setting as outlined in the AAFP, ACEP ultrasound practice guidelines.
This course is taught by leading family medicine, internal medicine, and emergency medicine ultrasound experts and incorporates comprehensive lectures focused on outpatient and inpatient clinical applications, interactive case... |
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Build Your Own Case Study | Redefining MASLD/MASH Care: Personalized Strategies for Assessment, Diagnosis and Management
Health Care Providers (HCPs) in the endocrinology specialty setting are challenged to be knowledgeable of the pathophysiology of MASLD (metabolic dysfunction-associated steatotic liver disease) and MASH (metabolic dysfunction-associated steatohepatitis) and its associated risk factors, as well as feel confident around how and when to order noninvasive diagnostic tests to prevent the emergence of more severe complications and stay on top of current guidelines and emerging treatment options.
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POCUS for Internal Medicine - Live Course
The POCUS for Internal Medicine Live Training Course provides participants a strong foundation to perform and/or interpret all of the core ultrasound applications in an urban and rural internal medicine setting as outlined in the AAFP, ACEP ultrasound practice guidelines.
This course is taught by leading family medicine, internal medicine, and emergency medicine ultrasound experts and incorporates comprehensive lectures focused on outpatient and inpatient clinical applications, interactive ... |
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Recent Developments in the Treatment of Clear Cell, Renal Cell Carcinoma: Essential Insights and Updates for the Healthcare Team
Target Audience
Oncology, Managed care and Specialty Pharmacists and Oncology Nurses/Nurse Practitioners
Program Overview
The goal of this educational initiative is to equip oncology nurse practitioners and nurses, as well as oncology, managed care, and specialty care pharmacists with the knowledge to apply findings from risk scoring systems used to stratify cases of clear cell renal cell carcinoma for treatment selection, differentiate among an expanding array of combination regimens con... |
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Psoriasis Prime Time: The Role of TYK Inhibition in Psoriasis
Target Audience
This activity has been designed to address the educational needs of dermatologists, dermatology nurse practitioners, and PAs. It may also be of benefit to primary care clinicians, rheumatologists, and other healthcare practitioners who are interested in the treatment of psoriasis.
Program Overview
In this edition of Psoriasis Prime Time, the faculty reviews the unique mechanism of action for allosteric tyrosine kinase 2 (TYK2) inhibitors compared with Janus kinase inhibito... |
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Practice-Changing Advances in the Management of Hemophilia
STATEMENT OF NEED
Hemophilia is an inherited bleeding disorder in which the blood does not clot properly, causing affected individuals to experience spontaneous bleeding as well as bleeding after injuries or surgery. The 2 most common types are hemophilia A, caused by low levels of clotting factor VIII; and hemophilia B, caused by low levels of clotting factor IX. The standard treatment for hemophilia involves replacing the missing blood clotting factor by infusing commercially prepared facto... |
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Podcast: Practice-Changing Advances in the Management of Hemophilia
STATEMENT OF NEED
Hemophilia is an inherited bleeding disorder in which the blood does not clot properly, causing affected individuals to experience spontaneous bleeding as well as bleeding after injuries or surgery. The 2 most common types are hemophilia A, caused by low levels of clotting factor VIII; and hemophilia B, caused by low levels of clotting factor IX. The standard treatment for hemophilia involves replacing the missing blood clotting factor by infusing commercially prepared facto... |
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New Guidelines and Novel Treatments for PAH: Taking a Forward-Looking Data Dive Into the Pool of Emerging Therapies
Target Audience
This educational activity has been designed to meet the needs of cardiologists, pulmonologists, rheumatologists, and other physicians, including those in primary care and internal medicine, as well as physician assistants, nurse practitioners, and other healthcare providers who may be involved in managing care for patients with pulmonary arterial hypertension (PAH).
Program Overview
Discoveries about the pathogenesis of pulmonary arterial hypertension (PAH) revealed key mo... |
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Sharing Real-World Experiences with New Rett Syndrome Therapies
Target Audience
The educational design of this activity addresses the needs of neurologists, pediatric neurologists, and specialty NP/PAs involved in the treatment of patients with Rett syndrome.
Program Overview
Integrating newer agents for the treatment of Rett syndrome into clinical practice can be challenging, particularly in community settings. In this activity, an expert panel will convene featuring a neurologist from an International Rett Syndrome Foundation (IRSF)-designated cente... |
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Distinguishing and Managing Early-Stage Alzheimer’s Disease (AD): Leveraging Interdisciplinary Collaboration for Prompt Identification and Optimal Patient Management
Target Audience
This activity is designed to meet the educational needs of healthcare providers involved in the diagnosis and continued care of patients with Alzheimer’s disease, including neurologists, geriatricians, psychiatrists, primary care physicians, nurses, and other multidisciplinary team members.
Program Overview
This educational activity is designed to provide clinicians who manage patients with Alzheimer’s disease with current information on diagnosis and management, inclu... |
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33rd Annual Primary Care Conference, Session 1
Emmerse yourself in the allure of Kiawah Island, South Carolina, while enhancing your medical expertise at the 33rd Annual Primary Care Conference, CEC's oldest and most popular CME conference. Attend one of two sessions: June 23 - 27 or June 30 - July 4 at the prestigious Kiawah Island Golf Resort. This event allows primary care clinicians to stay updated in rapidly changing therapeutic areas with time to explore Kiawah Island's pristine beaches and lush marshlands, where CEC has be... |
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Autosomal Dominant Polycystic Kidney Disease " Understanding the Disease and Improving Treatment Adherence and Outcome
Target Audience
This activity is designed to meet the educational needs of nephrologists, primary care providers, and providers who care for patients with kidney disease.
Program Overview
In the real-world setting, treatment adherence in patients with autosomal dominant polycystic kidney disease (ADPKD) can be a challenge. This CME program will discuss the diagnosis and management of ADPKD as well as strategies on improving treatment adherence. Patients’ perspectives on how to deal with... |
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Gastroenterology 2025 - LIVE STREAMING
The Comprehensive 2025 Gastroenterology Update
This highly rated Harvard Medical School CME program ensures participants are current with state-of-the-art GI strategies and clinical practices. It covers recent advances and their impact on clinical approaches and on patient outcomes. Updates, best practices, and new guidelines are presented by nationally recognized GI experts and master clinicians.
Practical, Results-Driven Education
Highlights of the 2025 program include:
• The new... |
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33rd Annual Primary Care Conference, Session 2
Elevate your medical practice at the 33rd Annual Primary Care Conference, CEC's longest-running and most popular CME event, hosted at the prestigious Kiawah Island Golf Resort. Held during two sessions from June 23 - 27 or June 30 - July 4, you have the flexibility to choose the dates that best fit your schedule.
Prepare for enlightening morning sessions led by expert faculty, covering a comprehensive array of topics tailored to the evolving needs of primary care clinicians. Dive into ... |
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Refining Management of CMV After Transplant: Exploiting Recent Advances to Alleviate Patient Burden: A Care Team Forum®
Target Audience
Transplant, infectious disease, internal medicine, nephrologists, primary care, pharmacy clinicians, advanced practice providers, and surgeons managing patients with CMV
Program Overview
Cytomegalovirus (CMV) is one of the most common infectious complications in solid organ transplant (SOT) recipients. During this activity, the faculty will discuss best practices for prevention and treatment of CMV post-transplant and provide clinical pearls for managing difficult-to-tr... |
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Cleveland Clinic 27th Annual Diabetes Therapeutics, Technology and Surgery (Online Streaming On Demand)
For over a quarter century, Cleveland Clinic has been at the forefront of continuing education regarding the treatment and management of diabetes. Its world class faculty has designed the 27th Annual Diabetes Therapeutics, Technology and Surgery to provide up-to-date reviews of strategies and research relevant to this disease and its complications. The goal of this activity is to increase practitioners’ competence and clinical performance in the management of type 1 and type 2 diabetes. A... |
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Identifying Needs and Opportunities to Improve Clinical Outcomes in the Identification, Characterization, and Management of Low-Grade Serous Ovarian Cancer
Target Audience
This activity is designed to meet the educational needs of oncologists, obstetrician/gynecologists, gastroenterologists, and primary care physicians to ensure confidence in the diagnosis, characterization, and management of low-grade serous ovarian cancer, including through enrollment in ongoing clinical trials.
Program Overview
This enduring educational activity will provide insight into evidence-based approaches for clinical and pathological assessment of patients with d... |
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Diagnosis and Evidence-based Prevention of Chronic Obstructive Pulmonary Disease Exacerbations
Target Audience
The primary target audience for this activity are Pulmonology clinicians (MDs/DOs/NPs/PAs) based in the U.S.
Program Overview
Many patients do not receive appropriate and timely treatment for chronic obstructive pulmonary disease (COPD) because of underdiagnoses, diagnostic delays, or misdiagnoses as other respiratory conditions such as asthma. An expert panel of pulmonologists will identify and address important gaps in the differential diagnosis and management of COPD. O... |
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Lp(a) and LDL-C Management: Exploring Divergent Perspectives
Target Audience
The intended audience for this activity is cardiologists, endocrinologists, internists, pharmacists, nurses, and other healthcare professionals involved in the management of patients with hyperlipidemia and other cardiovascular risk factors.
Program Overview
Lp(a) and LDL-C Management: Exploring Divergent Perspectives is a continuing education (CE) initiative aimed at broadening healthcare professionals' understanding of the complex nature of hyperlipidemia management... |
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Teaming Up to Treat Rett Syndrome: The Importance of Fostering a Multidisciplinary Approach to Patient Care
Target Audience
The educational design of this activity addresses the needs of neurologists, pediatric neurologists and specialty NP/PAs involved in the treatment of patients with Rett syndrome.
Program Overview
With newer therapies now available for the treatment of Rett syndrome, it is essential that the challenges of managing patients with rare diseases, such as Rett syndrome in resource-poor areas or “care deserts” be addressed.
Join a neurologist and a gastroenterologist from ... |
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PEERx - Ethics Module 1: Priority of Pharmacy Ethics in Healthcare
This Educational Activity is provided by Pharmacy Ethics, Education, and Resources (PEER) and is designed to educate healthcare professionals on ethics to improve patient safety.
Ethics is a top priority in pharmacy across all practice areas. It is essential for pharmacy staff to grasp the ethical principles endorsed by pharmacy leadership. Through discussing ethics and learning from historical incidents in pharmacy involving ethical violations, pharmacy professionals can proactively pre... |
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PEERx - Ethics Module 2: Evolution of Healthcare Ethics
This Educational Activity is provided by Pharmacy Ethics, Education, and Resources (PEER) and is designed to educate healthcare professionals on ethics to improve patient safety.
The healthcare landscape is rapidly evolving, requiring healthcare professionals to adapt accordingly. Having effective decision-making strategies is crucial for making ethical choices in current situations and future possibilities. Practicing these strategies in a calm setting can help professionals make sound ... |
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PEERx - Ethics Module 3: Importance of Business Ethics to the Pharmacy Community
This Educational Activity is provided by Pharmacy Ethics, Education, and Resources (PEER) and is designed to educate healthcare professionals on ethics to improve patient safety.
Pharmacy presents its own set of challenges. When business is intertwined, it gives rise to numerous ethical dilemmas. This program aims to introduce the ethical principles within the pharmacy and business realms, as well as to outline a robust decision-making framework. By reviewing various scenarios, owners, s... |
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PEERx - Ethics Module 6: Preparing Pharmacy For The Next Crisis
This Educational Activity is provided by Pharmacy Ethics, Education, and Resources (PEER) and is designed to educate healthcare professionals on ethics to improve patient safety.
The emergence of the COVID-19 virus in 2020 plunged the world into an unprecedented pandemic. Pharmacists found themselves at the forefront of this global health emergency, facing it with minimal preparation and guidance. With existing emergency plans proving ineffective during a worldwide shutdown, this initiat... |
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Psoriasis With Scalp Involvement in a Patient With Skin of Color
Target Audience
This activity has been designed to address the educational needs of dermatologists, dermatology nurse practitioners, and PAs. It may also be of benefit to primary care clinicians, rheumatologists, and other healthcare practitioners who are interested in the treatment of psoriasis.
Program Overview
This case will discuss the treatment of psoriasis in patients with skin of color, highlighting the challenges of treating scalp psoriasis. The faculty will review the mechanism o... |
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Comprehensive Management of Von Hippel-Lindau Disease: Genetic and Oncological Perspectives
STATEMENT OF NEED
Von Hippel-Lindau disease (VHL) is an autosomal dominant disease in which germline pathogenic variants in the VHL gene predispose individuals to specific types of benign tumors, malignant tumors, and cysts in multiple organs, including clear cell renal cell carcinoma (RCC), renal cysts, central nervous system hemangioblastomas, retinal hemangioblastomas, pancreatic tumors and cysts, endolymphatic sac tumors, and cystadenomas of the epididymis and broad ligament (NIH, 2024). ... |
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Thyroid Eye Disease Mastery: Multidisciplinary Approaches to Diagnosis and Treatment
Thyroid eye disease (TED) is a multifactorial autoimmune disease with widely varied signs and symptoms. It is believed to result from the stimulation of several receptors located in the orbital fibroblasts and is usually associated with hyperthyroidism. However, 5% of patients with TED have hypothyroidism, and 5% have no sign of thyroid disease; thus, it is frequently misdiagnosed. Misdiagnosis can place patients at risk for disfigurement and permanent vision loss, because treatment is most ef... |
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Psoriasis Prime Time: TYK Inhibition in Hard-to-Treat Psoriasis
Target Audience
This activity has been designed to address the educational needs of dermatologists, dermatology nurse practitioners, and PAs. It may also be of benefit to primary care clinicians, rheumatologists, and other healthcare practitioners who are interested in the treatment of psoriasis.
Program Overview
In this edition of Psoriasis Prime Time, the faculty reviews the use of allosteric tyrosine kinase 2 (TYK2) inhibitors in the treatment of hard-to-treat psoriasis, including the ... |
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Occurrence and Disease Course of RSV Illness in Adults
Target Audience
This educational activity is intended for US-based healthcare professionals who care for older adults, including pulmonologists, geriatricians, and additional primary care providers (family physicians, internists, physician associates, nurse practitioners and other nursing professionals, and pharmacists).
Program Overview
Respiratory syncytial virus (RSV) is a highly contagious seasonal lower respiratory tract infection (LRTI) characterized by cough, runny nose, sneezing, ... |
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Addressing Underutilization of Cardioprotective GLP-1 RAs for T2D in Specialty Practice.
The complexity of patients with T2D combined with the overwhelming amount of outcomes data complicates the treatment decision matrix exponentially and clinical inertia persists. This self-paced, interactive education includes a learning assessment followed by customizable content repository designed to sharpen your ability to individualize therapeutic targets and glucose-lowering regimens based on multiple factors, including the presence of comorbidities, such as obesity or cardiovascular risk... |
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9th Annual Internal Medicine in Primary Care Conference
Prepare to embark on an extraordinary voyage of discovery and rejuvenation aboard the Celebrity Edge, where the 9th Annual Internal Medicine in Primary Care Conference awaits amidst the awe-inspiring landscapes of Alaska. From July 25 to August 1, 2025, immerse yourself in the natural splendor of the Inside Passage as you sail through pristine fjords, past towering glaciers, and alongside majestic wildlife. This unique cruise offers a perfect blend of educational enrichment and leisurely explo... |
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How the Patient Experience Should Inform Treatment Selection: Reframing Expectations in EoE for HCPs and Patients
Eosinophilic esophagitis (EoE) has been steadily increasing in prevalence and incidence over the past three decades. Today, EoE has evolved from a rare case-reportable condition to a disease that is commonly encountered in the clinic and endoscopy suite and is a major cause of upper gastrointestinal morbidity and increasing healthcare costs.
Delays in diagnosis persist and management of the disease can be complex. While significant advances in the treatment of EoE have been made, studies s... |
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DETECT" Advances in the Delayed-Onset of Type 1 Diabetes: Strategies to Improve Awareness and Care for the Practicing Clinician
Target Audience
This activity is designed to meet the educational needs of Pediatric Endocrinologists, Adult Endocrinologists, Pediatricians, Primary Care Providers (PCPs), and Endocrine Nurses.
Program Overview
This educational program focuses on the early screening, detection, and advances in the treatment of early-stage type 1 diabetes (T1D). Through this enduring Grand Rounds session, clinicians will be able to review the importance and benefits of early screening, how to screen &... |
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Managing Obesity in Adolescent Patients Your Top 10 Questions Answered
The rate of obesity in children and adolescents is increasing, posing significant physical and mental health challenges through childhood and adolescence and into adulthood. Recently, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been approved for use in patients as young as 12 years, and it is critical that clinicians initiate both lifestyle management and pharmacologic therapies as early as possible. Dr. Fatima Stanford discusses 10 common questions asked about managing obesity ... |
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Nuclear Medicine and Molecular Imaging Update
The Mid East Chapter of the Society of Nuclear Medicine and Molecular Imaging’s historic 50th Annual Conference presents nuclear medicine’s latest trends, advances and procedures. Adapted for the enduring material audience, Nuclear Medicine and Molecular Imaging Update features a dozen faculty members presenting this specialty’s impact on imaging, cardiology, neurology, endocrinology, oncology, rheumatology, pediatrics and much more. Practice enhancements and professional development w... |
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Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 1
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 2
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). Multicancer early detection (MCED) is an emerging form of blood-based testing that utilizes cancer biomarkers in the blood to screen for multiple cancers simultaneously (ACS, 2024). Currently, numerous clinical trials are investiga... |
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Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 3
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States (ACS, 2024; Pinsky & Berg, 2012; USPSTF, 2024). Multicancer early detection (MCED) is a novel form of blood-based ca... |
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Podcast - Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 1
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Podcast - Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 2
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Podcast - Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 3
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Advances In the Delayed-Onset of Type 1 Diabetes: Strategies to Improve Awareness and Care for the Practicing Clinician - Part 3
Target Audience
This activity is designed to meet the educational needs of Pediatric and Adult Endocrinologists, Pediatricians, Primary Care Providers, and Endocrine Nurses.
Program Overview
During this program, experts will present overviews of the importance of early screening and staging for type 1 diabetes (T1D), strategies and practical pearls for screening and follow-up, how to intervene early with disease-modifying therapies to delay progression to clinical T1D, as well as ongoing ... |
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Navigating the Evolving Standards of Newly Diagnosed Multiple Myeloma Treatment: Exploring the Evidence on New Combination Strategies
ACTIVITY DESCRIPTION
The goal of treatment for newly diagnosed multiple myeloma (NDMM) patients is achieving the deepest possible remission, which typically involves aiming for minimal residual disease negativity. Frontline therapy for NDMM is evolving to include novel induction regimens with anti-CD38 antibodies, which have been shown to yield improved depth of response after induction. These new frontline treatments vary in induction regimen composition and use of transplant, consolidation,... |