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How the Patient Experience Should Inform Treatment Selection: Reframing Expectations in EoE for HCPs and Patients
Eosinophilic esophagitis (EoE) has been steadily increasing in prevalence and incidence over the past three decades. Today, EoE has evolved from a rare case-reportable condition to a disease that is commonly encountered in the clinic and endoscopy suite and is a major cause of upper gastrointestinal morbidity and increasing healthcare costs.
Delays in diagnosis persist and management of the disease can be complex. While significant advances in the treatment of EoE have been made, studies s... |
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Artificial Intelligence in Radiology (Streaming Online & USB Drive)
Artificial Intelligence in Radiology will provide imagers of all experience levels with the introductory information and foundational skills necessary to thrive in a future impacted by AI integrated healthcare. Developed in collaboration with Artificial Intelligence Medical Education (AiME), this activity is designed to demonstrate AI’s radiology applications, its potential to enhance clinical practice and its limitations. As such, this practical and clinically relevant overview will detail... |
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Optimizing Early Nutrition for Long-Term Benefits
Sharon Donovan, PhD, RD, and Michael Georgieff, MD, review what is currently known about the influence of nutrition during the first 1,000 days of growth and development. Human milk"the model for optimal nutrition"is discussed, including its nutritive and nonnutritive components, how it functions as a dynamic biological system, and the latest breastfeeding guidelines. The implications of suboptimal early nutrition are addressed, along with the role of pediatric clinicians in providin... |
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DETECT" Advances in the Delayed-Onset of Type 1 Diabetes: Strategies to Improve Awareness and Care for the Practicing Clinician
Target Audience
This activity is designed to meet the educational needs of Pediatric Endocrinologists, Adult Endocrinologists, Pediatricians, Primary Care Providers (PCPs), and Endocrine Nurses.
Program Overview
This educational program focuses on the early screening, detection, and advances in the treatment of early-stage type 1 diabetes (T1D). Through this enduring Grand Rounds session, clinicians will be able to review the importance and benefits of early screening, how to screen &... |
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A Primer on IgE-Mediated Food Allergies, With Drs. Kelly Cleary and Barbara Yawn
In this CE podcast, developed in collaboration with Food Allergy Research & Education (FARE), experts review the pathophysiological underpinnings of IgE-mediated food allergies and discuss the importance of shared decision-making and interdisciplinary approaches to optimize patient care. |
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Advances in the Management of IgE-Mediated Food Allergies, With Drs. Kelly Cleary and Robert Wood
In this podcast, expert clinicians will discuss the efficacy and safety of traditional and emerging treatments as well as evidence-based guidance for managing patients with immunoglobulin E (IgE)-mediated food allergies. |
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Beyond Avoidance: IgE-Mediated Food Allergies " Therapeutic Innovations to the Rescue
In the United States, food-induced allergic reactions are the leading cause of anaphylaxis in hospital emergency departments. Among these, immunoglobulin E (IgE)-mediated food allergies are the most common, and they pose significant risks, including cardiac arrest and respiratory failure. Traditionally, treatment options for IgE-mediated food allergies have been primarily limited to food avoidance and anaphylaxis prevention. However, recent years have brought the FDA approval of the first oral... |
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Establishing Frameworks for Precision Medicine in NTRK Fusion-Positive Advanced Solid Tumors
Despite significant advancements over the past decade, significant unmet needs persist for patients with NTRK-positive locally advanced or metastatic solid tumors. In addition, there is ongoing debate about the importance of testing for genomic alterations in rare cancers, or those that rarely occur in common cancers. However, evolving molecular testing procedures and emerging therapeutic options targeting NTRK fusions offer new pathways for the detection and treatment of these cancers. To he... |
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Are You Up to Speed? Test Your Knowledge on Pneumococcal Vaccination in Adults
Despite widespread availability of pneumococcal vaccines designed to reduce the risks for infection and invasive pneumococcal disease, coverage remains suboptimal among older adults and those with underlying medical conditions and risk factors. The development of pneumococcal conjugate vaccines offers new opportunities for improved protection against pneumococcal disease, but are you current with the latest evidence and guideline recommendations? If you're a puzzle enthusiast, dive into t... |
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Musculoskeletal Ultrasound: Introduction - Live Course
The Musculoskeletal Ultrasound: Introduction Live Training Course provides participants a comprehensive introduction to musculoskeletal ultrasound. This course is taught by leading musculoskeletal ultrasound experts and incorporates comprehensive lectures with live scanning demonstrations on upper and lower extremity applications for diagnostic and ultrasound guided injection/aspiration techniques. Extensive hands-on scanning sessions feature a 3:1 participant to faculty ratio with live standa... |
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Musculoskeletal Ultrasound: Introduction with Interventional Cadaver Lab - Live Course
The Musculoskeletal Ultrasound: Introduction with Interventional Cadaver Lab Training Course provides participants a comprehensive introduction to musculoskeletal ultrasound. This course is taught by leading musculoskeletal ultrasound experts and incorporates comprehensive lectures covering anatomy, pathology, and ultrasound-guided injection/aspiration techniques. Live scanning demonstrations are included for each upper and lower extremity joint.
Extensive hands-on scanning sessions feature... |
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Management of Metastatic Colorectal Cancer
Stacey Cohen, MD, explores the significance of molecular profiling and tumor markers in personalizing immunotherapy for metastatic colorectal cancer. She also delves into the evolving landscape of targeted therapies, discussing the nuances and considerations of different options to optimize patient outcomes. |
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Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 1
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 2
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). Multicancer early detection (MCED) is an emerging form of blood-based testing that utilizes cancer biomarkers in the blood to screen for multiple cancers simultaneously (ACS, 2024). Currently, numerous clinical trials are investiga... |
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Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 3
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States (ACS, 2024; Pinsky & Berg, 2012; USPSTF, 2024). Multicancer early detection (MCED) is a novel form of blood-based ca... |
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Podcast - Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 1
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Podcast - Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 2
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Podcast - Optimizing Cancer Screening With MCED Technologies: From Science to Practical Application - Module 3
STATEMENT OF NEED
Approximately 2 million new cancer cases are expected in the United States in 2024, with an anticipated 611,720 deaths (ACS, 2024). Screening is associated with earlier stage at diagnosis and improved outcomes (Kim et al, 2011; Plumb et al, 2016). However, cancers that are not routinely screened for account for 78% of all cancer deaths in the United States, and even among cancers that do have standard tests, factors such as low awareness, lack of available facilities, and in... |
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Musculoskeletal Ultrasound: Advanced Interventions & Regenerative Medicine - Live Course
The Musculoskeletal Ultrasound: Advanced Interventions & Regenerative Medicine Training Course is taught by leading experts in the field of MSK ultrasound. This course takes your musculoskeletal ultrasound skills to the next level with a focus on advanced diagnostic and interventional skills including spine, peripheral nerve, tendinopathy and ultrasound-guided tenotomy. Regenerative medicine applications including prolotherapy, platelet-rich plasma (PRP), bone-marrow aspirate concentrate (... |
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Making The Call in Lower-Risk MDS Exploring Treatments That Improve Outcomes & Decrease Transfusion Burden
Myelodysplastic syndromes (MDSs) are among the most common hematologic malignancies and are characterized by their risk of progression to acute leukemia. Although patients with lower-risk MDS (LR-MDS) have longer life expectancies compared to those with high-risk disease, their disease course is not without challenges. In fact, symptoms related to anemia are very common in this population and lead to poor quality of life. Fortunately, therapies are now available to treat the anemia associated ... |
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Advances In the Delayed-Onset of Type 1 Diabetes: Strategies to Improve Awareness and Care for the Practicing Clinician - Part 3
Target Audience
This activity is designed to meet the educational needs of Pediatric and Adult Endocrinologists, Pediatricians, Primary Care Providers, and Endocrine Nurses.
Program Overview
During this program, experts will present overviews of the importance of early screening and staging for type 1 diabetes (T1D), strategies and practical pearls for screening and follow-up, how to intervene early with disease-modifying therapies to delay progression to clinical T1D, as well as ongoing ... |
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Mastering Suboptimal Treatment Response in nAMD
In this Master Class case, Dr. David Eichenbaum discusses the management of a 69-year-old White man with neovascular age-related macular degeneration who receives a suboptimal treatment response to initial anti-vascular epithelial growth factor therapy. |
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Mastering Treatment-Refractory nAMD
In this Master Class case, Dr. Michael Singer discusses the management of an 82-year-old Hispanic man with treatment-refractory neovascular age-related macular degeneration. |
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Mastering Treatment-Naive DME
In this Master Class case, Dr. Mark R. Barakat discusses the management of a 76-year-old White man with treatment-naive diabetic macular edema. |
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Mastering Suboptimal Treatment Response in DME
In this Master Class case, Dr. W. Lloyd Clark discusses the management of a 75-year-old Black woman with diabetic macular edema who has a suboptimal treatment response to initial anti-vascular epithelial growth factor therapy. |
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Mastering Treatment-Refractory DME
In this Master Class case, Dr. Diana Do discusses the management of a 58-year-old White woman with treatment-refractory diabetic macular edema. |
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Recognizing and Confirming Potential ATTR in Your Patients
Target Audience
This activity is designed to meet the educational needs of physicians, allied health practitioners, and students interested in complex cardiovascular and thoracic conditions and those who care for patients with ATTR.
Program Overview
This activity will cover early diagnosis and intervention for transthyretin amyloidosis (ATTR), which is critical, yet does not occur, typically as a consequence of the rarity and heterogeneity of the disease and limited awareness on the part ... |
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Navigating the Evolving Standards of Newly Diagnosed Multiple Myeloma Treatment: Exploring the Evidence on New Combination Strategies
ACTIVITY DESCRIPTION
The goal of treatment for newly diagnosed multiple myeloma (NDMM) patients is achieving the deepest possible remission, which typically involves aiming for minimal residual disease negativity. Frontline therapy for NDMM is evolving to include novel induction regimens with anti-CD38 antibodies, which have been shown to yield improved depth of response after induction. These new frontline treatments vary in induction regimen composition and use of transplant, consolidation,... |
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ASCVD Clinical Research Updates Targeting Residual Inflammation in Patients with ASCVD and CKD
Emerging evidence and scientific advancements are revealing pathophysiologic mechanisms correlated with systemic inflammation and the development of atherosclerotic cardiovascular disease (ASCVD). Patients with chronic kidney disease (CKD) are at high risk for developing ASCVD. Novel anti-inflammatory therapies are showing efficacy at reducing inflammation and development of ASCVD, and are adding to the treatment options beyond the usual lipid-lowering agents. As new clinical evidence and tar... |
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Geographic Atrophy Secondary to Age-Related Macular Degeneration: Innovative Therapies for Sight Revival
Multimodal imaging is key for the early detection and monitoring of geographic atrophy (GA) secondary to age-related macular degeneration (AMD). Optical coherence tomography has recently been recommended by an international consensus to be the primary imaging method for the detection of atrophy in eyes. Once diagnosed, timely therapeutic intervention should be initiated with recently FDA-approved therapies that target components of the complement cascade. When optimally integrated into persona... |
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Improving the Diagnosis and Management of Pulmonary Progressive Fibrosis (PPF): A Focus on Systemic Sclerosis Interstitial Lung Disease (SSc-ILD) and Idiopathic Pulmonary Fibrosis (IPF)
Target Audience
This activity is designed to meet the educational needs of rheumatologists, pulmonologists, and advanced practice providers.
Program Overview
This activity features an interactive case-based format where you can review questions to determine best practices in diagnosing and managing PPF, SSc-ILD, and IPF. This session offers real-life examples to help differentiate diseases within the Pulmonary Progressive Fibrosis (PPF) group, such as Idiopathic Pulmonary Fibrosis (IPF) a... |
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Bunion-Like Toes and Tumor Like Swellings " Recognize FOP and Improve Patient Outcomes in the Era of Disease Specific Therapy
Target Audience
This activity is designed to meet the educational needs of healthcare providers in pediatrics, primary care, oncology, surgery, radiology, acute care, emergency medicine, rheumatology, and infectious disease.
Program Overview
Bunion-like toes present at birth and tumor-like swellings in a young child are diagnostic signs of fibrodysplasia ossificans progressive (FOP), a disease with recent advances made in therapy. Upon completion of the course, learners should be able to ... |
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Podcast: Multidisciplinary Task Force and Position Statement: Mitigating Disease Burden and Health Care Disparities in Relapsed/Refractory Multiple Myeloma
STATEMENT OF NEED
With the complex and rapidly evolving treatment landscape of multiple myeloma, it is vital that clinicians not only understand factors for informing selection of current and emerging combination and sequential therapeutic strategies, but also employ interdisciplinary strategies for reducing disparities in relapsed/refractory multiple myeloma care. The development of novel therapeutic options has significantly improved treatment outcomes for patients with relapsed/refractor... |
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Bridging the Health Gaps in Hereditary Angioedema: Demystifying Disparities, Enhancing Quality of Life, and Implementing Effective Prophylactic Solutions
Hereditary angioedema (HAE) is a rare, life-threatening disorder characterized by recurrent, unpredictable episodes of bradykinin-induced swelling. In this presentation, Dr. Marc Reidl, Clinical Director of the US Hereditary Angioedema Association (HAEA) Angioedema Center, reviews multiple underrecognized factors that contribute to health disparities among patients with HAE, including delays in diagnosis and multifaceted differences among racial and ethnic groups, socioeconomic status levels, ... |
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Ace the Case: A 77-Year-Old Man With Chronic Heartburn and Persistent Abdominal Pain
This educational activity will utilize a case study to discuss a 77-year-old man who presents with a history of chronic heartburn and 3 months of persistent abdominal pain. |
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Ace the Case: A 38-Year-Old Man With Resistant Hypertension
This educational activity will utilize a case study to discuss a 38-year-old man with resistant hypertension. |
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Ace the Case: A 47-Year-Old Woman With Lethargy, Confusion, and Muscle Weakness
This educational activity will utilize a case study to discuss a 47-year-old woman with lethargy, confusion, and muscle weakness. |
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Hypertrophic Cardiomyopathy: Unmasking Disparities and Forging a Path to Equitable Care
This comprehensive continuing education (CE) monograph delves into the complexities of HCM, an autosomal dominant genetic disorder marked by increased left ventricular hypertrophy. This condition can lead to significant health complications, such as heart failure, arrhythmias, stroke, and sudden cardiac death. Despite the impact of HCM on patient health and well-being, a gap persists in the understanding of the racial/ethnic and gender-based disparities among healthcare professionals. This gap... |
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Hypertrophic Cardiomyopathy: Unmasking Disparities and Forging a Path to Equitable Care
This comprehensive continuing education (CE) monograph delves into the complexities of HCM, an autosomal dominant genetic disorder marked by increased left ventricular hypertrophy. This condition can lead to significant health complications, such as heart failure, arrhythmias, stroke, and sudden cardiac death. Despite the impact of HCM on patient health and well-being, a gap persists in the understanding of the racial/ethnic and gender-based disparities among healthcare professionals. This gap... |
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Treating SCLC in the Relapsed/Refractory Setting: Giving Patients a Voice About Second-Line Therapy
SCLC is aggressive in nature with a high recurrence rate following initial treatment and a propensity to become resistant to conventional therapies. Early detection is critical, but many patients are diagnosed at an advanced stage where prognosis is poor. Progress in the second-line setting offers new hope for improving patient outcomes, but the rapid pace at which these advances are occurring present challenges for effectively integrating novel therapies into patient care. In fact, research s... |
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Chronic Rhinosinusitis with Nasal Polyps Navigating New Pathways to Better Patient Outcomes
Chronic inflammatory diseases of the upper and lower airways, especially CRSwNP and asthma, have been tied to significant risks and burdens for affected patients and frequently require close coordinated multidisciplinary care. Targeted agents designed to interrupt inflammatory cytokine signaling have been examined in clinical trials and evidence suggests these options can provide a range of benefits in patients with CRSwNP and related comorbidities. During this interactive activity, expert fac... |
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Inherited Retinal Diseases: Navigating the Future of Diagnostics and Emerging Therapies
The differential diagnosis and workup of a suspected inherited retinal disease (IRD) can be challenging, requiring the expertise of the multidisciplinary healthcare team. Guidelines released in 2022 by the American Academy of Ophthalmology provide recommendations and clinical genetic assessments for patients with IRDs. Genetic counseling is essential to help patients understand the genetic test results, their implications for prognosis, family planning, and therapeutic decisions. Genetic testi... |
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nAMD and DME: Novel Treatment Plans to Prioritize Real-World Visual Improvements
Frequent intravitreal injections of anti-vascular endothelial growth factor (VEGF) therapies can significantly improve visual and anatomical outcomes for many patients with neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME). However, the requisite high number of treatments often leads to less-than-ideal results compared to outcomes reported in major clinical trials, largely due to the demanding treatment schedule. Adopting tailored treatment plans, along with ... |
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Patient Point of View: PDE4 Inhibitors for the Treatment of Adult Plaque Psoriasis
Psoriasis is a chronic, immune-mediated inflammatory skin disorder that significantly impacts affected individuals’ quality of life. The most common subtype is plaque psoriasis, characterized by erythematous to violaceous plaques covered with scales. Due to the substantial symptom burden of plaque psoriasis and challenges surrounding medication tolerability and adherence, innovative treatment options are needed. Phosphodiesterase-4 (PDE4) inhibitors, which play a key role in the inflammatory... |
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Epstein-Barr Virus-Positive Post-Transplant Lymphoproliferative Disorders: Addressing Unmet Needs with Emerging Therapies
In this Hematology Dialogues, Epstein-Barr Virus-Positive Post-Transplant Lymphoproliferative Disorders: Addressing Unmet Needs with Emerging Therapies, participants will learn about the epidemiology and burden of Epstein-Barr Virus-positive (EBV+) and post-transplant lymphoproliferative disorders (PTLD), differentiate between current and emerging prognostic scoring systems for EBV+ and PTLD to inform treatment decisions, and evaluate the latest clinical evidence of emerging treatment options ... |
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Thyroid Eye Disease: Unmasking and Taming What’s in Disguise
Thyroid eye disease (TED) is a complex autoimmune-mediated inflammatory disorder of the orbit that is associated with a spectrum of signs and symptoms and varying levels of severity. Early diagnosis and initiation of appropriate treatment are imperative for preventing progression to severe disease and potential vision loss. However, diagnosis can be challenging. Traditional treatments for TED, such as steroids, radiotherapy, and surgery, all relieve symptoms but do not alter the course of dise... |
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Overcoming the Hurdles: Advances in the Management of Hemophilia
In this fast-moving, 1-hour accredited activity, Craig Kessler, MD, and Guy Young, MD, share their thoughts and experience with clotting factor concentrates, recombinant factor, factor VIII mimetics, rebalancing agents, and gene therapies. The safety and efficacy of late-phase investigational products are also discussed as these agents have the potential to address unmet needs and further transform patient care. |
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Cushing’s Syndrome Treatment Research Highlights: ENDO 2024
Target Audience
This activity has been designed to meet the educational needs of physicians specializing in endorcrinology, radiology, neurosurgery, and general practice. Other members of the care team may also participate.
Program Overview
This 30-minute CME program highlights the latest clinical research about Cushing’s syndrome and Cushing’ disease.
Learning Objectives
After participating in the activity, learners should be better able to:
Describe the latest research being ... |
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Solving the TED Puzzle: Answering Your Questions on Diagnosis to Decision-Making
Thyroid eye disease (TED) is a complex, autoimmune-mediated, inflammatory disorder of the orbit that presents with a range of symptoms, including ocular pain, dysmotility, and changes in ocular structure and function. The disease severely impacts patients' quality of life, often resulting in persistent discomfort, altered appearance, and impaired vision even after the acute phase subsides. Traditional treatments such as steroids, radiotherapy, and surgery, do not alter the disease's ... |
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Extending Dosing Intervals in Retinal Disease: Patient Perspectives and Clinical Insights to Guide Your Practice
Neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME) are increasingly prevalent retinal diseases that pose significant challenges in ophthalmic care. While anti-vascular endothelial growth factor (VEGF) therapies have greatly improved visual outcomes for patients with these conditions, real-world data indicate that many patients receive suboptimal treatment and monitoring, resulting in poorer visual outcomes. Newer therapeutic options have been developed to exte... |
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