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Warm Autoimmune Hemolytic Anemia (wAIHA)
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis.
Current recommendations for managing people with wAIHA are largely based on case series and retrospective studies involving off-label medications. Also, while there are currently no medications specifically approved to treat wAIHA, data are emerging on new... |
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Leveraging the Growing Arsenal of Adjuvant Therapies for Early-Stage NSCLC
In this activity, Dr. Helena A. Yu, Associate Attending Physician at Memorial Sloan Kettering Cancer Center, will provide insights into strategies for leveraging the growing arsenal of adjuvant therapies for early-stage non"small cell lung cancer (NSCLC), including treatment selection and adverse event management. Start the activity now!
STATEMENT OF NEED
Lung cancer is the second most commonly diagnosed cancer and the leading cause of death for men and women worldwide. In the Unite... |
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Pathology and Oncology Expert Perspectives in the Management of Triple-Negative Breast Cancer: Case Explorations and Answers to FAQs
STATEMENT OF NEED
Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for approximately 10% to 15% of breast cancer diagnoses and is characterized by the absence of estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2 (HER2). TNBC is more common in Black women and in women under the age of 40 (ACS, 2023). Compared with other subtypes of invasive breast cancer, TNBC has high rates of metastasis and a poor prognosis. Due to the lack ... |
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Managing Immune Related Adverse Events to Ensure Optimal Cancer Immunotherapy Outcomes: The Nurse’s View
STATEMENT OF NEED
Immune checkpoint inhibitors, which alter immune regulatory pathways and promote cell-mediated destruction of tumor cells, have revolutionized the treatment of cancer in recent years, with numerous therapeutic agents approved and several targets under investigation (Chennamadhavuni et al, 2022). However, up to 90% of patients receiving immune checkpoint inhibitors experience immune-related adverse events, which can affect a wide variety of organ systems and can occur at any ... |
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Cushing’s Disease Research Highlights: ENDO 2023
This 30-minute CME program highlights the latest clinical research about Cushing’s disease.
Cushing’s disease is caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary tumor that leads to excessive levels of cortisol.
This CME program, hosted by Lisa Machtigall, MD, Clinical Director, Neuroendocrine & Pituitary Tumor Clinical Center at Massachusetts General Hospital, and Associate Professor of Medicine at Harvard Medical School, provides an overview of the latest cli... |
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Recurrent and Metastatic HNSCC: New Insights and Real-World Evidence for Improved Patient Outcomes
STATEMENT OF NEED
Head and neck cancers represent a heterogeneous group of tumors that originate in the lip/oral cavity, hypopharynx, oropharynx, nasopharynx, and larynx. An estimated 66,470 new cases are diagnosed in the United States annually, and 15,050 people die of the disease (Siegel et al, 2022). Approximately 90% of cases are classified as head and neck squamous cell carcinoma (HNSCC). Treatment of HNSCC is complicated by numerous factors, including differing therapeutic strategies ... |
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Exploring Novel Treatments for Rett Syndrome
STATEMENT OF NEED
Rett syndrome is a rare, debilitating neurodevelopmental disorder almost always associated with a spontaneous mutation in the methyl-CpG-binding protein 2 (MECP2) gene on the X-chromosome. Affected individuals experience loss of purposeful hand skills, abnormalities in gait, loss of spoken language, and stereotypic hand movements, with more severe manifestations including seizures, autistic features, autonomic nervous system dysfunction, breathing abnormalities, sleep dist... |
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Sexual Harassment Prevention
Sexual Harassment (required CE by the State of Illinois) |
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Navigating pain management, safe opioid prescribing, and opioid use disorder
This program is presented in six thirty minute sessions that can be completed individually.
The sessions are:
Session 1: Pain Taxonomy, pathogenesis, and assessment
Session 2: Developing a patient-centered pain treatment plan
Session 3: Non-opioid analgesics: Evidence and clinical pearls
Session 4: Opioid analgesics: From A to Z
Session 5: Clinical use of opioids: Safe prescribing and appropriate monitoring
Session 6: The exit strategy: When the treatment becomes the ... |
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Best of Lipid Forum®: Examining the Role of Lp(a) as a Risk Factor in Atherosclerotic Cardiovascular Disease
Lipoprotein(a) [Lp(a)] is a low-density lipoprotein particle that is associated with poor cardiovascular prognosis due to its pro-atherogenic, pro-thrombotic, pro-inflammatory and pro-oxidative properties. Unfortunately, traditional lipid-lowering therapy does not provide sufficient Lp(a) reduction. High levels of Lp(a) are an independent and causal risk factor for atherosclerotic cardiovascular disease (ASCVD) through mechanisms associated with increased atherogenesis, inflammation, and throm... |
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Best of Lipid Forum®: Examining the Role of Lp(a) as a Risk Factor in Atherosclerotic Cardiovascular Disease
Lipoprotein(a) [Lp(a)] is a low-density lipoprotein particle that is associated with poor cardiovascular prognosis due to its pro-atherogenic, pro-thrombotic, pro-inflammatory and pro-oxidative properties. Unfortunately, traditional lipid-lowering therapy does not provide sufficient Lp(a) reduction. High levels of Lp(a) are an independent and causal risk factor for atherosclerotic cardiovascular diseases (ASCVD) through mechanisms associated with increased atherogenesis, inflammation, and thro... |
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Introduction to Culturally and Linguistically Appropriate Services (CLAS) and Minority Health Disparities
This course helps you incorporate into practice the National Culturally and Linguistically Appropriate Services (CLAS) standards of the USDHHS Office of Minority Health.
Outcome Objectives:
As a result of completing this activity, the participant will be better able to:
- Describe the National Culturally and Linguistically Appropriate Services (CLAS) standards of the USDHHS Office of Minority Health and how they impact the ethical responsibilities of medical service providers.
- Defi... |
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Skin Cancer Education for Primary Care
This comprehensive course on skin cancer will help you improve your ability to diagnose and manage skin lesions, the most common of all cancers.
Outcome Objectives:
As a result of completing this activity, the participant will be better able to:
- Understand the biology of ultraviolet radiation and methods to protect the skin.
- Demonstrate increased proficiency in the management of potentially malignant skin lesions.
- Make early diagnoses of skin cancers, particularly melanoma.... |
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Acromegaly: Improving Timely Diagnosis, Assessment, and Treatment
Acromegaly, caused by excessive growth hormone production from the anterior pituitary gland, results in disproportionate growth of body tissues and other metabolic dysfunctions. With causes divided into primary GH excess, ectopic or iatrogenic GH excess, and excess growth hormone-releasing hormone (GHRH), adult patients have the characteristic facial features of a large lower jaw, a prominent forehead, and large hands and feet. These features occur after the growth plates are fused, distinguis... |
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Ace the Case: A 34-Year-Old Woman With Painful Swallowing
This educational activity will utilize a case study to discuss a 34-year-old woman with painful swallowing that has been progressively worsening for the past few days and is associated with anorexia, nausea, and epigastric abdominal pain. |
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Real-World Perspectives in Managing CLL Treatment
Management options for chronic lymphocytic leukemia (CLL) have expanded in recent years. The emergence of new immunotherapeutic and targeted agents for both the first-line and relapsed/refractory settings"though of course beneficial for CLL patients"represents a challenge to clinicians, who must navigate the indicated uses, mechanisms of action, and toxicity profiles of these new agents. In determining optimal treatment plans, clinicians are also confronted with significant advances ... |
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The Role of the Clinical Pharmacist in the Management of Multiple Myeloma
Multiple myeloma (MM) is the second most common hematologic malignancy in the United States and is characterized by monoclonal proliferation of malignant plasma cells that accumulate within the bone marrow. The incidence of MM has increased in recent years, in part due to the revised definition of symptomatic MM from the International Myeloma Working Group in 2014. The National Cancer Institute estimated a total of 34,470 new cases in 2022, with 12,640 deaths. Despite significant advancements ... |
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Geographic Atrophy: Rapid Response from ARVO
Geographic atrophy (GA) is a pathological deterioration of the retina seen in the late stages of age-related macular degeneration (AMD). It affects 20% of people with AMD, and its prevalence increases exponentially with age. Until recently, there were no treatment options for GA, but investigation into the complement system and its role in the pathogenesis of GA has led to targeted therapies that have revolutionized the treatment paradigm. Because of the recent approval of one of these therapi... |
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Anesthesiology Update 2024 - LIVE STREAMING or IN PERSON
The Comprehensive 2024 Anesthesiology Update
Cardiac, Regional, Office-Based, Thoracic, Obstetric, Neuro, and Pediatric
Anesthesiology Update will be held on May 6-10, 2024. You have the option to attend either online as the course is live streamed or in person in Boston, MA.
In the past year, there have been a number of very significant clinical changes that affect the practice of anesthesiology. This comprehensive CME program provides a special and timely opportunity for anesthesiolo... |
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Diabetes Update 2024 - LIVE STREAMING
This highly rated Harvard Medical School CME course offers practical strategies to address the medical and systemic challenges to optimal care and updates that ensure you can deliver state-of-the-art care for your patients with diabetes.
PROGRAM HIGHLIGHTS
This program affords you the opportunity to learn from leaders in the field of diabetes who are distinguished for their outstanding teaching, knowledge, and innovations in clinical care.
Participants can rely on this program for compreh... |
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Hot Topics in Lupus: SLE Pathophysiology
Despite the known short- and long-term adverse outcomes related to glucocorticoid use, patients with SLE are still taking moderate to high daily doses of steroids. Fortunately, 2 biologic therapies aimed at different therapeutic targets in the type I interferon pathway and with better safety profiles than glucocorticoids are currently available for use. These biologics, along with off-label immunosuppressants, can be implemented in customized ways to mitigate or eliminate the use of glucocort... |
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Hot Topics in Lupus: Individualizing Steroid-Sparing Regimens
Despite the known short- and long-term adverse outcomes related to glucocorticoid use, patients with SLE are still taking moderate to high daily doses of steroids. Fortunately, 2 biologic therapies aimed at different therapeutic targets in the type I interferon pathway and with better safety profiles than glucocorticoids are currently available for use. These biologics, along with off-label immunosuppressants, can be implemented in customized ways to mitigate or eliminate the use of glucocort... |
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Hot Topics in Lupus: Targeted Biologic Treatment Options
Despite the known short- and long-term adverse outcomes related to glucocorticoid use, patients with SLE are still taking moderate to high daily doses of steroids. Fortunately, 2 biologic therapies aimed at different therapeutic targets in the type I interferon pathway and with better safety profiles than glucocorticoids are currently available for use. These biologics, along with off-label immunosuppressants, can be implemented in customized ways to mitigate or eliminate the use of glucocort... |
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Eyeing the Options for Treating Meibomian Gland Dysfunction and Dry Eye Disease
Dry eye disease (DED) is highly prevalent but frequently underdiagnosed and subsequently undertreated. Studies have demonstrated that meibomian gland dysfunction (MGD) is a leading cause of the development and progression of evaporative DED, caused by a deficient tear film lipid layer that leads to increased tear evaporation. New and emerging treatments with novel mechanisms of action are being investigated that manage the signs and symptoms of DED associated with MGD and offer the potential f... |
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Warm Autoimmune Hemolytic Anemia (wAIHA)
Target Audience
This activity has been designed to meet the educational needs of physicians specializing in hematology and hematology-oncology. Other members of the care team may also participate.
Program Overview
Warm autoimmune hemolytic anemia (wAIHA) is the most common type (60-70%) of autoimmune hemolytic anemia (AIHA). In most cases, wAIHA is due an immunoglobulin G (IgG) autoantibody that binds to red blood cells (RBC), leading to hemolysis.
Current recommendations for managing ... |
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Sports Medicine 2024 -LIVE STREAMING
The Comprehensive 2024 Sports Medicine Update
State-of-the-Art Approaches to the Diagnosis, Treatment, Rehabilitation, and Prevention of Sports Injuries
This Harvard Medical School CME program, which is among the highest-rated HMS CME courses, provides a special and timely opportunity to hear directly from world-renowned physician specialists (physiatrists, orthopedists, radiologists), team physicians and athletic trainers for the Boston Red Sox, New England Revolution, and New England P... |
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Optimizing Outcomes in ALS: Best Practices in Screening, Diagnosis, and Treatment
"Optimizing Outcomes in ALS: Best Practices in Screening, Diagnosis, and Treatment" is a modular continuing education series led by Dr. Richard Bedlack, a nationally recognized ALS expert. This self-navigation program focuses on amyotrophic lateral sclerosis (ALS), providing healthcare professionals with valuable insights and evidence-based strategies to enhance outcomes in ALS care. Participants have the flexibility to choose their own track and explore various modules, covering cli... |
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Graft vs Host Disease: Novel Management Strategies for a Chronic Condition
Target Audience
The intended audience for this activity is transplant specialists, oncologists, hematologists, and other healthcare professionals involved in the treatment of patients with GVHD.
Program Overview
This enduring activity takes learners on a compelling journey in managing chronic graft-versus-host disease (cGVHD) by explaining the evidence-based diagnostic criteria for cGVHD for prompt diagnosis; discussing the clinical safety and efficacy data of recently approved and invest... |
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In Case You Missed: Utilizing the Muscarinic System to Optimize Treatment Options for Schizophrenia
Schizophrenia is an incurable, neuropsychiatric disease characterized by difficulties thinking and communicating clearly as well as psychosis (ie, “positive” symptoms); difficulty functioning socially (ie, “negative” symptoms); and cognitive impairment. As many as 34% of patients with schizophrenia have treatment-resistant schizophrenia, defined as continuing symptoms despite at least 2 trials of appropriate antipsychotic treatment, and most people do not recover from it. Patients with... |
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The Pharmacist’s Role in Managing Patients with Worsening Heart Failure
Pharmacists play a vital role in the management of patients with heart failure (HF). Navigate through this interactive self-directed, pharmacist-targeted activity designed to optimize your decision-making to apply the most recent clinical trial data and guidance seen in real-world HF practice, particularly in patients with worsening HF and after recent HF hospitalization. Expert perspectives and insights cover guideline-directed medical therapy (GDMT) implementation and additional adjustment t... |
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Build Your Own Case Study | Obesity: Treating the Whole Patient
Activity Description
Obesity is a chronic, progressive, relapsing disease that impacts health and quality of life. In individuals with obesity, there are many contributors to its development and persistence, including lifestyle, social, and economic factors. If left untreated, obesity can be a primary driver of serious health consequences. By treating obesity first, complications arising from obesity may improve or resolve. Given the severity of the disease, there is a need for clinicians in ... |
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Answering the Call in Severe Asthma Expanding Roles for Biologic Treatment Regimens
This enduring Call-a-Colleague™ educational program will guide attendees through the long-term management of severe asthma. Expert faculty will provide actionable recommendations on evaluation strategies that consider underlying mechanism of disease, data on newer biologic treatment options, and most importantly, the use of these therapies in current day practice. Interspersed throughout the program are brief Call-a-Colleague™ video calls in which faculty consult with their specialist coll... |
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Navigating New Evidence in the Treatment of HER2-Expressing Metastatic Breast Cancer in Rural and Underserved Communities
Target Audience
This activity is designed specifically for oncologists, advanced practice providers, and other members of the healthcare team who serve patients from rural and underserved communities.
Program Overview
Over the past decades, the emergence of novel targeted therapies in combination with endocrine therapy has improved outcomes for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer. However, oncology clinicians in rural and ... |
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Navigating the Evolving Treatment Landscape of Renal Cell Carcinoma to Ensure Equitable Access to Quality Care
Target Audience
This activity is designed specifically for oncologists, advanced practice providers, and other members of the healthcare team who serve patients from rural and underserved communities.
Program Overview
Therapeutic options for metastatic renal cell carcinoma (RCC) have expanded over the last decade and now include targeted therapies as well as immunotherapies. However, workforce shortages, low rates of recruitment into clinical trials, racial and socioeconomic inequities, a... |
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Emerging Therapies, Novel Mechanisms, and New Hope in the Treatment of PAH
The treatment landscape of pulmonary arterial hypertension (PAH) is poised to change dramatically in the near future. Designed with your questions in mind, this digital FAQ index offers succinct and relevant information for all practicing pulmonology and cardiology learners. What are some of the emerging therapies for PAH, and how do they differ from current treatment options? Which emerging therapies may be disease modifying? What clinical trial evidence is there for the treatments being inve... |
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Treating Obesity 2024: The Blackburn Course in Obesity Medicine - LIVE STREAMING
Education to Optimize Your Care of Adult, Adolescent, and Pediatric Patients with Obesity
This highly rated Harvard Medical School CME course delivers practical strategies to optimize the management of obesity and its many complications, and provides the most up-to-date approaches to obesity prevention and treatment.
Highlights of the 2024 program include:
• Update on using the newer GLP-1 based therapies
• Comprehensive evaluation of the patient with obesity
• Emerging precision me... |
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Pathways for Optimal Sequencing, Rapid Initiation, and Titration of Therapy in Patients with Heart Failure
Many patients with heart failure (HF) do not receive foundational treatment although these therapies reduce morbidity and mortality risks. The initiation and optimization of guideline-directed medical therapies (GDMT) can be challenging, but clinical practice guidelines and algorithms are available to assist.
Navigate through this interactive self-directed CME activity to apply the most recent clinical trial data and guidance to patient-specific factors seen in real-world practice. Expert p... |
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Answers to the Questions You May Not be Asking: Treating Ulcerative Colitis Considerate of Patient-Centric Factors
Are you aware of the latest evidence-based strategies in ulcerative colitis (UC)? Looking to expand your ability to incorporate patient-centric factors into selection of therapy for UC? Navigate through this novel, interactive self-directed activity designed to optimize your decision making in selection of therapy for UC. View expert perspectives and insights who can help you apply newer strategies such as treat-to-target (T2T) and therapeutic drug monitoring (TDM) for the treatment for your ... |
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The Importance of Early Recognition of Tay-Sachs and Sandhoff Disease
Faculty experts Jeanine Jarnes, PharmD, and Chester Whitley, MD, PhD, delve into the rare and difficult to diagnose GM2-gangliosidoses Tays-Sachs and Sandhoff diseases. Following a discussion of the etiology and pathophysiology of these diseases, the faculty use real-life cases to illustrate the various phenotypes of these conditions, as well as key presenting signs and symptoms. Diagnostic approaches are discussed, alongside current standards of care, including supportive and palliative treat... |
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Intensive Review of Internal Medicine - IN PERSON or LIVE STREAMING
The Acclaimed Clinical Update and Board Review
With more than 150 lectures, case discussions, and board preparation sessions, this CME program is one of the most comprehensive reviews of internal medicine offered by the clinical faculty of Harvard Medical School.
It offers accelerated learning:
- For clinicians seeking a practical and comprehensive review that ensures you are up to date across all major fields of internal medicine:
• Newer options for diagnosis: what to choose, w... |
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Cardiovascular Considerations in COPD Management
With cardiovascular disease coexisting in up to 60% of COPD cases, optimal management of each disease is imperative to successful patient outcomes. In this Phone-a-Friend episode, Dr. MeiLan Han consults with Dr. Ty Gluckman to discuss a patient with a 5-year history of COPD and cardiovascular risk factors that may be contributing to his persistent symptoms. |
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A Patient With Severe Asthma in Need of Additional Control
Severe asthma is thought to affect about 5% to 10% of the total population of patients with asthma. The detrimental consequences of uncontrolled severe asthma are significant, leading to serious exacerbations, deterioration of lung function, and pronounced impact on quality of life. The emergence of biologic therapies has revolutionized the treatment of severe asthma. Dr. Flavia Hoyte consults with Dr. Njira Lugogo to discuss a patient with poorly controlled, late-onset severe disease who may... |
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Endometriosis Boot Camp: Exploring Patient Perspectives to Improve Diagnosis and Management
Endometriosis is one of the most common benign gynecologic conditions that occur during a woman’s reproductive years. Despite the high prevalence of this disease, a large proportion of women with endometriosis remain undiagnosed and untreated. Unfortunately, even after diagnosis and treatment, recurrent and persistent pain are common and represent a significant challenge for patients and health care providers. Guided by our expert faculty, Endometriosis Boot Camp: Exploring Patient Perspecti... |
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Managing the Patient With Severe Asthma and Common Comorbidities
Comorbid disease is common amongst patients with asthma and may lead to worsening asthma symptoms if not properly identified and managed. Furthermore, some patients may not respond to their first biologic treatment option, confounding management and selection of next line therapy. Dr. Njira Lugogo consults with Dr. Flavia Hoyte to discuss a treatment plan for her patient with severe, allergic asthma and comorbid disease. |
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Clinical Consults in Severe Asthma: New Approaches to Targeted Therapy
As management options for the treatment of severe asthma continue to expand with the addition of effective biologic therapies, physicians often consult colleagues for advice on complex cases or challenging issues. This 3-episode Phone-a-Friend series features 3 expert physicians asking and answering questions related to the management of severe asthma. The series will cover a variety of topics, including patient symptom assessment; disease phenotyping; rationale for treatment escalation or swi... |
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Prurigo Nodularis: Recognizing, Diagnosing and Treating a Rare but Debilitating Disease
Prurigo Nodularis is a rare, chronic skin disorder that causes substantial patient burden, but is often overlooked or misdiagnosed and, until recently, had no medications approved by the US Food and Drug Administration. The interprofessional faculty share their real-world perspectives on the diagnosis and treatment of patients with prurigo nodularis to reduce patient burden of disease and improve health outcomes. Highlighting pathophysiologic mechanisms, the faculty discuss the evolving pharma... |
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Intensive Review of Nephrology - LIVE STREAMING
With over 70 interactive lectures, case discussions, board preparation sessions, and supplementary lectures, this CME program provides a comprehensive review of state-of-the-art nephrology practices offered by the clinical faculty of Harvard Medical School.
It offers accelerated learning for:
- Clinicians seeking a practical and comprehensive review that ensures they are up to date across all major areas of nephrology:
• The latest options for diagnosis: what to choose, when, and wh... |
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Contemporary Issues in the Management of Patients With Primary Biliary Cholangitis: An Interprofessional Approach
An interprofessional faculty of gastroenterology clinicians discuss real-world issues in managing patients with primary biliary cholangitis. Two mini-lectures serve as the foundation for understanding the diagnostic evaluation and risk factors of primary biliary cholangitis. Three cases foster a robust discussion, among the 5 faculty, of clinical decision-making around the roles, benefits, and limitations of approved and investigational pharmacologic treatment options. The program format foste... |
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Promoting Equitable Oral Health in Patients of Color
There are many vulnerable and underserved populations in oral health. Gaps in health and health care are often caused by the disconnect between medical and dental care and a fragmented system that has left 74 million people without dental insurance, leading to knowledge gaps and a lack of dental-medical collaboration and coordination in patient care. These issues are exacerbated in patients of color, often due to interpersonal racism.
This CME Outfitters BriefCase will feature patient case ... |
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Irregular Care: Racial Inequities in the Management of Cardiac Rhythm Disorders
Structural racism and classism leads to many of the social determinants of health (SDoH) that cause disparities in cardiovascular (CVD) care, such as unequal preventative care, heart arrythmia treatment, and research inclusion. Interpersonal racism, including unconscious bias, worsens disproportionate CVD care, and is also a stand-alone factor for this health inequity. Underrepresented minority (URM) patients – particularly Black/African American individuals – are less likely to receive, b... |
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